“Living a normal life”: a qualitative study of patients’ views of medication withdrawal in rheumatoid arthritis

by Kenneth F. Baker, John D. Isaacs, Ben Thompson
Published 2019-06-01

Basic Mechanisms of JAK Inhibition

by Chung MA Lin, Faye AH Cooles, John D. Isaacs
Published 2020-01-01

Evaluating Awareness and Perception of Botnet Activity within Consumer Internet-of-Things (IoT) Networks

by Christopher D. McDermott, John P. Isaacs, Andrei V. Petrovski
Published 2019-02-01

Introducing New Biosimilars Into Current Treatment Algorithms

by John D. Isaacs, Thomas Dörner, Tore K. Kvien, Arnold Vulto
Published 2016-07-01

Albumin-linked prostate-specific antigen-activated thapsigargin- and niclosamide-based molecular grenades targeting the microenvironment in metastatic castration-resistant prostate...

by Emmanuel S. Akinboye, W. Nathaniel Brennen, Samuel R. Denmeade, John T. Isaacs
Published 2019-01-01

4-Hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]-1,2-dihydroquinoline-3-carboxamide

by Emmanuel S. Akinboye, Ray J. Butcher, Sema Ozturk Yildirim, John T. Isaacs
Published 2014-03-01

Lack of association between clinical and ultrasound measures of disease activity in rheumatoid arthritis remission

by Kenneth F. Baker, Ben Thompson, Dennis W. Lendrem, Adam Scadeng, Arthur G. Pratt, John D. Isaacs
Published 2020-05-01

Concise Review: Mesenchymal Stem Cell‐Based Drug Delivery: The Good, the Bad, the Ugly, and the Promise

by Timothy E. G. Krueger, Daniel L. J. Thorek, Samuel R. Denmeade, John T. Isaacs, W. Nathaniel Brennen
Published 2018-09-01

IL-6 Mediated Transcriptional Programming of Naïve CD4+ T Cells in Early Rheumatoid Arthritis Drives Dysregulated Effector Function

by Laura A. Ridgley, Amy E. Anderson, Nicola J. Maney, Najib Naamane, Andrew J. Skelton, Catherine A. Lawson, Catherine A. Lawson, Paul Emery, Paul Emery, John D. Isaacs, John D. Isaacs, Ruaidhrí J. Carmody, Arthur G. Pratt, Arthur G. Pratt
Published 2019-07-01

Loss of androgen receptor-dependent growth suppression by prostate cancer cells can occur independently from acquiring oncogenic addiction to androgen receptor signaling.

by Jason M D'Antonio, Donald J Vander Griend, Lizamma Antony, George Ndikuyeze, Susan L Dalrymple, Shahriar Koochekpour, John T Isaacs
Published 2010-07-01

Phenotypic and Transcriptomic Analysis of Peripheral Blood Plasmacytoid and Conventional Dendritic Cells in Early Drug Naïve Rheumatoid Arthritis

by Faye A. H. Cooles, Faye A. H. Cooles, Amy E. Anderson, Amy E. Anderson, Andrew Skelton, Andrew Skelton, Arthur G. Pratt, Arthur G. Pratt, Mariola S. Kurowska-Stolarska, Mariola S. Kurowska-Stolarska, Iain McInnes, Iain McInnes, Catharien M. U. Hilkens, Catharien M. U. Hilkens, John D. Isaacs, John D. Isaacs
Published 2018-05-01

FcγRIIIa expression on monocytes in rheumatoid arthritis: role in immune-complex stimulated TNF production and non-response to methotrexate therapy.

by Dawn L Cooper, Stephen G Martin, James I Robinson, Sarah L Mackie, Christopher J Charles, Jackie Nam, YEAR Consortium, John D Isaacs, Paul Emery, Ann W Morgan
Published 2012-01-01

Targeting of tolerogenic dendritic cells to heat-shock proteins in inflammatory arthritis

by Rachel Spiering, Manon A. A. Jansen, Matthew J. Wood, Anshorulloh A. Fath, Oliver Eltherington, Amy E. Anderson, Arthur G. Pratt, Willem van Eden, John D. Isaacs, Femke Broere, Catharien M. U. Hilkens
Published 2019-11-01

In Reply

by W. Nathaniel Brennen, Michael T. Schweizer, Hao Wang, Trinity J. Bivalacqua, Alan W. Partin, Su Jin Lim, Carolyn Chapman, Rehab Abdallah, Oren Levy, Neil A. Bhowmick, Jeffrey M. Karp, Angelo De Marzo, John T. Isaacs, Samuel R. Denmeade
Published 2019-07-01

Resistance to androgen receptor signaling inhibition does not necessitate development of neuroendocrine prostate cancer

by W. Nathaniel Brennen, Yezi Zhu, Ilsa M. Coleman, Susan L. Dalrymple, Lizamma Antony, Radhika A. Patel, Brian Hanratty, Roshan Chikarmane, Alan K. Meeker, S. Lilly Zheng, Jody E. Hooper, Jun Luo, Angelo M. De Marzo, Eva Corey, Jianfeng Xu, Srinivasan Yegnasubramanian, Michael C. Haffner, Peter S. Nelson, William G. Nelson, William B. Isaacs, John T. Isaacs
Published 2021-04-01

Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis

by Frank Penkava, Martin Del Castillo Velasco-Herrera, Matthew D. Young, Nicole Yager, Lilian N. Nwosu, Arthur G. Pratt, Alicia Lledo Lara, Charlotte Guzzo, Ash Maroof, Lira Mamanova, Suzanne Cole, Mirjana Efremova, Davide Simone, Andrew Filer, Chrysothemis C. Brown, Andrew L. Croxford, John D. Isaacs, Sarah Teichmann, Paul Bowness, Sam Behjati, M. Hussein Al-Mossawi
Published 2020-09-01

BIOlogical Factors that Limit sustAined Remission in rhEumatoid arthritis (the BIO-FLARE study): protocol for a non-randomised longitudinal cohort study

by Fiona Rayner, Amy E. Anderson, Kenneth F. Baker, Christopher D. Buckley, Bernard Dyke, Sally Fenton, Andrew Filer, Carl S. Goodyear, Catharien M. U. Hilkens, Shaun Hiu, Sean Kerrigan, Mariola Kurowska-Stolarska, Fiona Matthews, Iain McInnes, Wan-Fai Ng, Arthur G. Pratt, Jonathan Prichard, Karim Raza, Stefan Siebert, Deborah Stocken, M. Dawn Teare, Stephen Young, John D. Isaacs
Published 2021-07-01

Arthritis prevention in the pre-clinical phase of RA with abatacept (the APIPPRA study): a multi-centre, randomised, double-blind, parallel-group, placebo-controlled clinical trial...

by Mariam Al-Laith, Marianna Jasenecova, Sonya Abraham, Aisla Bosworth, Ian N. Bruce, Christopher D. Buckley, Coziana Ciurtin, Maria-Antonietta D’Agostino, Paul Emery, Hill Gaston, John D. Isaacs, Andrew Filer, Benjamin A. Fisher, Thomas W. J. Huizinga, Pauline Ho, Clare Jacklin, Heidi Lempp, Iain B. McInnes, Arthur G. Pratt, Andrew Östor, Karim Raza, Peter C. Taylor, Dirkjan van Schaardenburg, Dharshene Shivapatham, Alison J. Wright, Joana C. Vasconcelos, Joanna Kelly, Caroline Murphy, A. Toby Prevost, Andrew P. Cope
Published 2019-07-01

Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies

by Phillip Lord, Rachel Spiering, Juan C. Aguillon, Amy E. Anderson, Silke Appel, Daniel Benitez-Ribas, Anja ten Brinke, Femke Broere, Nathalie Cools, Maria Cristina Cuturi, Julie Diboll, Edward K. Geissler, Nick Giannoukakis, Silvia Gregori, S. Marieke van Ham, Staci Lattimer, Lindsay Marshall, Rachel A. Harry, James A. Hutchinson, John D. Isaacs, Irma Joosten, Cees van Kooten, Ascension Lopez Diaz de Cerio, Tatjana Nikolic, Haluk Barbaros Oral, Ljiljana Sofronic-Milosavljevic, Thomas Ritter, Paloma Riquelme, Angus W. Thomson, Massimo Trucco, Marta Vives-Pi, Eva M. Martinez-Caceres, Catharien M.U. Hilkens
Published 2016-08-01

Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis.

by Jing Cui, Eli A Stahl, Saedis Saevarsdottir, Corinne Miceli, Dorothee Diogo, Gosia Trynka, Towfique Raj, Maša Umiċeviċ Mirkov, Helena Canhao, Helena Canhao, Katsunori Ikari, Chikashi Terao, Yukinori Okada, Sara Wedrén, Johan Askling, Hisashi Yamanaka, Shigeki Momohara, Atsuo Taniguchi, Koichiro Ohmura, Fumihiko Matsuda, Tsuneyo Mimori, Namrata Gupta, Manik Kuchroo, Ann W Morgan, John D Isaacs, Anthony G Wilson, Kimme L Hyrich, Marieke Herenius, Marieke E Doorenspleet, Paul-Peter Tak, J Bart A Crusius, Irene E van der Horst-Bruinsma, Gert Jan Wolbink, Piet L C M van Riel, Mart van de Laar, Henk-Jan Guchelaar, Nancy A Shadick, Cornelia F Allaart, Tom W J Huizinga, Rene E M Toes, Robert P Kimberly, S Louis Bridges, Lindsey A Criswell, Larry W Moreland, João Eurico Fonseca, Niek de Vries, Barbara E Stranger, Philip L De Jager, Soumya Raychaudhuri, Michael E Weinblatt, Peter K Gregersen, Xavier Mariette, Anne Barton, Leonid Padyukov, Marieke J H Coenen, Elizabeth W Karlson, Robert M Plenge
Published 2013-03-01