IL-36α Regulates Tubulointerstitial Inflammation in the Mouse Kidney

by Osamu Ichii, Junpei Kimura, Tadashi Okamura, Tadashi Okamura, Taro Horino, Teppei Nakamura, Teppei Nakamura, Hayato Sasaki, Yaser Hosny Ali Elewa, Yaser Hosny Ali Elewa, Yasuhiro Kon
Published 2017-10-01

Retrotransposition of long interspersed nucleotide element-1 is associated with colitis but not tumors in a murine colitic cancer model.

by Takeshi Otsubo, Tadashi Okamura, Teruki Hagiwara, Yukihito Ishizaka, Taeko Dohi, Yuki I Kawamura
Published 2015-01-01

Novel murine model of congenital diabetes: The insulin hyposecretion mouse

by Kenta Nakano, Rieko Yanobu‐Takanashi, Yuki Takahashi, Hayato Sasaki, Yukiko Shimizu, Tadashi Okamura, Nobuya Sasaki
Published 2019-03-01

Genetic locus responsible for diabetic phenotype in the insulin hyposecretion (ihs) mouse.

by Kenta Nakano, Rieko Yanobu-Takanashi, Yukiko Shimizu, Yuki Takahashi, Koki Hiura, Masaki Watanabe, Hayato Sasaki, Tadashi Okamura, Nobuya Sasaki
Published 2020-01-01

CANT1 deficiency in a mouse model of Desbuquois dysplasia impairs glycosaminoglycan synthesis and chondrocyte differentiation in growth plate cartilage

by Kazuki Kodama, Hiroaki Takahashi, Nobuyasu Oiji, Kenta Nakano, Tadashi Okamura, Kimie Niimi, Eiki Takahashi, Long Guo, Shiro Ikegawa, Tatsuya Furuichi
Published 2020-06-01

New Role for Growth/Differentiation Factor 15 in the Survival of Transplanted Brown Adipose Tissues in Cooperation with Interleukin-6

by Masako Oka, Norihiko Kobayashi, Kazunori Matsumura, Miwako Nishio, Kenta Nakano, Tadashi Okamura, Hitoshi Okochi, Tamiko Minamisawa, Kiyotaka Shiba, Kumiko Saeki
Published 2020-06-01

Hepatic Levels of DHA-Containing Phospholipids Instruct SREBP1-Mediated Synthesis and Systemic Delivery of Polyunsaturated Fatty Acids

by Daisuke Hishikawa, Keisuke Yanagida, Katsuyuki Nagata, Ayumi Kanatani, Yoshiko Iizuka, Fumie Hamano, Megumi Yasuda, Tadashi Okamura, Hideo Shindou, Takao Shimizu
Published 2020-09-01

Differential function of Themis CABIT domains during T cell development.

by Toshiyuki Okada, Takeshi Nitta, Kentaro Kaji, Akiko Takashima, Hiroyo Oda, Norimasa Tamehiro, Motohito Goto, Tadashi Okamura, Michael S Patrick, Harumi Suzuki
Published 2014-01-01

Phenotypic Characterization of LEA Rat: A New Rat Model of Nonobese Type 2 Diabetes

by Tadashi Okamura, Xiang Yuan Pei, Ichiro Miyoshi, Yukiko Shimizu, Rieko Takanashi-Yanobu, Yasumasa Mototani, Takao Kanai, Jo Satoh, Noriko Kimura, Noriyuki Kasai
Published 2013-01-01

Null mutation of the endothelin receptor type B gene causes embryonic death in the GK rat.

by Jinxi Wang, Ruihua Dang, Yoshiki Miyasaka, Kousuke Hattori, Daisuke Torigoe, Tadashi Okamura, Hassan T Tag-Ei-Din-Hassan, Masami Morimatsu, Tomoji Mashimo, Takashi Agui
Published 2019-01-01

Zfat-deficiency results in a loss of CD3ζ phosphorylation with dysregulation of ERK and Egr activities leading to impaired positive selection.

by Masahiro Ogawa, Tadashi Okamura, Shuhei Ishikura, Keiko Doi, Hiroshi Matsuzaki, Yoko Tanaka, Takeharu Ota, Kunihiro Hayakawa, Harumi Suzuki, Toshiyuki Tsunoda, Takehiko Sasazuki, Senji Shirasawa
Published 2013-01-01

Deletion of CDKAL1 affects mitochondrial ATP generation and first-phase insulin exocytosis.

by Mica Ohara-Imaizumi, Masashi Yoshida, Kyota Aoyagi, Taro Saito, Tadashi Okamura, Hitoshi Takenaka, Yoshihiro Akimoto, Yoko Nakamichi, Rieko Takanashi-Yanobu, Chiyono Nishiwaki, Hayato Kawakami, Norihiro Kato, Shin-ichi Hisanaga, Masafumi Kakei, Shinya Nagamatsu
Published 2010-12-01

Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport

by Tomomi Hashidate-Yoshida, Takeshi Harayama, Daisuke Hishikawa, Ryo Morimoto, Fumie Hamano, Suzumi M Tokuoka, Miki Eto, Miwa Tamura-Nakano, Rieko Yanobu-Takanashi, Yoshiko Mukumoto, Hiroshi Kiyonari, Tadashi Okamura, Yoshihiro Kita, Hideo Shindou, Takao Shimizu
Published 2015-04-01

Deletion of CDKAL1 affects high-fat diet-induced fat accumulation and glucose-stimulated insulin secretion in mice, indicating relevance to diabetes.

by Tadashi Okamura, Rieko Yanobu-Takanashi, Fumihiko Takeuchi, Masato Isono, Koichi Akiyama, Yukiko Shimizu, Motohito Goto, Yi-Qiang Liang, Ken Yamamoto, Tomohiro Katsuya, Akihiro Fujioka, Keizo Ohnaka, Ryoichi Takayanagi, Toshio Ogihara, Yukio Yamori, Norihiro Kato
Published 2012-01-01

GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection

by Shin-ichiro Hattori, Nobuyo Higshi-Kuwata, Jakka Raghavaiah, Debananda Das, Haydar Bulut, David A. Davis, Yuki Takamatsu, Kouki Matsuda, Nobutoki Takamune, Naoki Kishimoto, Tadashi Okamura, Shogo Misumi, Robert Yarchoan, Kenji Maeda, Arun K. Ghosh, Hiroaki Mitsuya
Published 2020-08-01

CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors

by Allah Nawaz, Aminuddin Aminuddin, Tomonobu Kado, Akiko Takikawa, Seiji Yamamoto, Koichi Tsuneyama, Yoshiko Igarashi, Masashi Ikutani, Yasuhiro Nishida, Yoshinori Nagai, Kiyoshi Takatsu, Johji Imura, Masakiyo Sasahara, Yukiko Okazaki, Kohjiro Ueki, Tadashi Okamura, Kumpei Tokuyama, Akira Ando, Michihiro Matsumoto, Hisashi Mori, Takashi Nakagawa, Norihiko Kobayashi, Kumiko Saeki, Isao Usui, Shiho Fujisaka, Kazuyuki Tobe
Published 2017-08-01