Combination of a Latency-Reversing Agent With a Smac Mimetic Minimizes Secondary HIV-1 Infection in vitro

by Shin-ichiro Hattori, Kouki Matsuda, Kiyoto Tsuchiya, Hiroyuki Gatanaga, Shinichi Oka, Kazuhisa Yoshimura, Hiroaki Mitsuya, Hiroaki Mitsuya, Kenji Maeda
Published 2018-09-01

Neutralization of SARS-CoV-2 with IgG from COVID-19-convalescent plasma

by Kenji Maeda, Nobuyo Higashi-Kuwata, Noriko Kinoshita, Satoshi Kutsuna, Kiyoto Tsuchiya, Shin-ichiro Hattori, Kouki Matsuda, Yuki Takamatsu, Hiroyuki Gatanaga, Shinichi Oka, Haruhito Sugiyama, Norio Ohmagari, Hiroaki Mitsuya
Published 2021-03-01

GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection

by Shin-ichiro Hattori, Nobuyo Higshi-Kuwata, Jakka Raghavaiah, Debananda Das, Haydar Bulut, David A. Davis, Yuki Takamatsu, Kouki Matsuda, Nobutoki Takamune, Naoki Kishimoto, Tadashi Okamura, Shogo Misumi, Robert Yarchoan, Kenji Maeda, Arun K. Ghosh, Hiroaki Mitsuya
Published 2020-08-01

A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency

by Manabu Aoki, Hironori Hayashi, Kalapala Venkateswara Rao, Debananda Das, Nobuyo Higashi-Kuwata, Haydar Bulut, Hiromi Aoki-Ogata, Yuki Takamatsu, Ravikiran S Yedidi, David A Davis, Shin-ichiro Hattori, Noriko Nishida, Kazuya Hasegawa, Nobutoki Takamune, Prasanth R Nyalapatla, Heather L Osswald, Hirofumi Jono, Hideyuki Saito, Robert Yarchoan, Shogo Misumi, Arun K Ghosh, Hiroaki Mitsuya
Published 2017-10-01

A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication

by Shin-ichiro Hattori, Nobuyo Higashi-Kuwata, Hironori Hayashi, Srinivasa Rao Allu, Jakka Raghavaiah, Haydar Bulut, Debananda Das, Brandon J. Anson, Emma K. Lendy, Yuki Takamatsu, Nobutoki Takamune, Naoki Kishimoto, Kazutaka Murayama, Kazuya Hasegawa, Mi Li, David A. Davis, Eiichi N. Kodama, Robert Yarchoan, Alexander Wlodawer, Shogo Misumi, Andrew D. Mesecar, Arun K. Ghosh, Hiroaki Mitsuya
Published 2021-01-01

Comparison of Rapid Antigen Tests for COVID-19

by Seiya Yamayoshi, Yuko Sakai-Tagawa, Michiko Koga, Osamu Akasaka, Ichiro Nakachi, Hidefumi Koh, Kenji Maeda, Eisuke Adachi, Makoto Saito, Hiroyuki Nagai, Kazuhiko Ikeuchi, Takayuki Ogura, Rie Baba, Kensuke Fujita, Takahiro Fukui, Fumimaro Ito, Shin-ichiro Hattori, Kei Yamamoto, Takato Nakamoto, Yuri Furusawa, Atsuhiro Yasuhara, Michiko Ujie, Shinya Yamada, Mutsumi Ito, Hiroaki Mitsuya, Norio Omagari, Hiroshi Yotsuyanagi, Kiyoko Iwatsuki-Horimoto, Masaki Imai, Yoshihiro Kawaoka
Published 2020-12-01

Antibody titers against SARS-CoV-2 decline, but do not disappear for several months

by Seiya Yamayoshi, Atsuhiro Yasuhara, Mutsumi Ito, Osamu Akasaka, Morio Nakamura, Ichiro Nakachi, Michiko Koga, Keiko Mitamura, Kazuma Yagi, Kenji Maeda, Hideaki Kato, Masanori Nojima, David Pattinson, Takayuki Ogura, Rie Baba, Kensuke Fujita, Hiroyuki Nagai, Shinya Yamamoto, Makoto Saito, Eisuke Adachi, Junichi Ochi, Shin-ichiro Hattori, Tetsuya Suzuki, Yusuke Miyazato, Shiho Chiba, Moe Okuda, Jurika Murakami, Taiki Hamabata, Kiyoko Iwatsuki-Horimoto, Hideaki Nakajima, Hiroaki Mitsuya, Norio Omagari, Norio Sugaya, Hiroshi Yotsuyanagi, Yoshihiro Kawaoka
Published 2021-02-01