A cytoplasmic tail determinant in HIV-1 Vpu mediates targeting of tetherin for endosomal degradation and counteracts interferon-induced restriction.

by Tonya Kueck, Stuart J D Neil
Published 2012-01-01

Inhibiting the Ins and Outs of HIV Replication: Cell-Intrinsic Antiretroviral Restrictions at the Plasma Membrane

by Toshana L. Foster, Suzanne Pickering, Stuart J. D. Neil
Published 2018-01-01

Antiviral Inhibition of Enveloped Virus Release by Tetherin/BST-2: Action and Counteraction

by Stuart J. D. Neil, Anna Le Tortorec, Suzanne Willey
Published 2011-05-01

HIV-1 Vpu promotes release and prevents endocytosis of nascent retrovirus particles from the plasma membrane.

by Stuart J D Neil, Scott W Eastman, Nolwenn Jouvenet, Paul D Bieniasz
Published 2006-05-01

Serine Phosphorylation of HIV-1 Vpu and Its Binding to Tetherin Regulates Interaction with Clathrin Adaptors.

by Tonya Kueck, Toshana L Foster, Julia Weinelt, Jonathan C Sumner, Suzanne Pickering, Stuart J D Neil
Published 2015-08-01

Preservation of tetherin and CD4 counter-activities in circulating Vpu alleles despite extensive sequence variation within HIV-1 infected individuals.

by Suzanne Pickering, Stephane Hué, Eun-Young Kim, Susheel Reddy, Steven M Wolinsky, Stuart J D Neil
Published 2014-01-01

Plasma membrane is the site of productive HIV-1 particle assembly.

by Nolwenn Jouvenet, Stuart J D Neil, Cameron Bess, Marc C Johnson, Cesar A Virgen, Sanford M Simon, Paul D Bieniasz
Published 2006-12-01

The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin.

by Claire Pardieu, Raphaël Vigan, Sam J Wilson, Alessandra Calvi, Trinity Zang, Paul Bieniasz, Paul Kellam, Greg J Towers, Stuart J D Neil
Published 2010-04-01

Species-specific activity of HIV-1 Vpu and positive selection of tetherin transmembrane domain variants.

by Matthew W McNatt, Trinity Zang, Theodora Hatziioannou, Mackenzie Bartlett, Ismael Ben Fofana, Welkin E Johnson, Stuart J D Neil, Paul D Bieniasz
Published 2009-02-01

Minimal impact of ZAP on lentiviral vector production and transduction efficiency

by Helin Sertkaya, Laura Hidalgo, Mattia Ficarelli, Dorota Kmiec, Adrian W. Signell, Sadfer Ali, Hannah Parker, Harry Wilson, Stuart J.D. Neil, Michael H. Malim, Conrad A. Vink, Chad M. Swanson
Published 2021-12-01

Translational Research in the Time of COVID-19-Dissolving Boundaries.

by Jonathan D Edgeworth, Rahul Batra, Gaia Nebbia, Karen Bisnauthsing, Eithne MacMahon, Malur Sudhanva, Sam Douthwaite, Simon Goldenberg, Geraldine O'Hara, Manu Shankar-Hari, Katie J Doores, Rocio Martinez-Nunez, Carolyn Hemsley, Nicholas M Price, Jill Lockett, Robert I Lechler, Stuart J D Neil, Michael H Malim
Published 2020-09-01

Upregulation of BST-2 by Type I Interferons Reduces the Capacity of Vpu To Protect HIV-1-Infected Cells from NK Cell Responses

by Jérémie Prévost, Suzanne Pickering, Mitchell J. Mumby, Halima Medjahed, Gabrielle Gendron-Lepage, Gloria G. Delgado, Brennan S. Dirk, Jimmy D. Dikeakos, Christina M. Stürzel, Daniel Sauter, Frank Kirchhoff, Frederic Bibollet-Ruche, Beatrice H. Hahn, Mathieu Dubé, Daniel E. Kaufmann, Stuart J. D. Neil, Andrés Finzi, Jonathan Richard
Published 2019-06-01

Translational Research in the Time of COVID-19—Dissolving Boundaries

by Jonathan D. Edgeworth, Rahul Batra, Gaia Nebbia, Karen Bisnauthsing, Eithne MacMahon, Malur Sudhanva, Sam Douthwaite, Simon Goldenberg, Geraldine O’Hara, Manu Shankar-Hari, Katie J. Doores, Rocio Martinez-Nunez, Carolyn Hemsley, Nicholas M. Price, Jill Lockett, Robert I. Lechler, Stuart J. D. Neil, Michael H. Malim, Carolyn B. Coyne
Published 2020-09-01

Comparative assessment of multiple COVID-19 serological technologies supports continued evaluation of point-of-care lateral flow assays in hospital and community healthcare setting...

by Suzanne Pickering, Gilberto Betancor, Rui Pedro Galão, Blair Merrick, Adrian W Signell, Harry D Wilson, Mark Tan Kia Ik, Jeffrey Seow, Carl Graham, Sam Acors, Neophytos Kouphou, Kathryn J A Steel, Oliver Hemmings, Amita Patel, Gaia Nebbia, Sam Douthwaite, Lorcan O'Connell, Jakub Luptak, Laura E McCoy, Philip Brouwer, Marit J van Gils, Rogier W Sanders, Rocio Martinez Nunez, Karen Bisnauthsing, Geraldine O'Hara, Eithne MacMahon, Rahul Batra, Michael H Malim, Stuart J D Neil, Katie J Doores, Jonathan D Edgeworth
Published 2020-09-01

Comparative performance of SARS-CoV-2 lateral flow antigen tests and association with detection of infectious virus in clinical specimens: a single-centre laboratory evaluation stu...

by Suzanne Pickering, PhD, Rahul Batra, MD, Blair Merrick, MBChB, Luke B Snell, MBBS, Gaia Nebbia, FRCPath, Sam Douthwaite, MRCP, Fiona Reid, MSc, Amita Patel, BSc, Mark Tan Kia Ik, BSc, Bindi Patel, BSc, Themoula Charalampous, PhD, Adela Alcolea-Medina, MPhil, Maria Jose Lista, PhD, Penelope R Cliff, PhD, Emma Cunningham, MSc, Jane Mullen, BSc, Katie J Doores, PhD, Jonathan D Edgeworth, ProfFRCPath, Michael H Malim, ProfDPhil, Stuart J D Neil, ProfPhD, Rui Pedro Galão, PhD
Published 2021-09-01