HIV-1 sequences in lentiviral vector genomes can be substantially reduced without compromising transduction efficiency

by Helin Sertkaya, Mattia Ficarelli, Nathan P. Sweeney, Hannah Parker, Conrad A. Vink, Chad M. Swanson
Published 2021-06-01

KHNYN is essential for the zinc finger antiviral protein (ZAP) to restrict HIV-1 containing clustered CpG dinucleotides

by Mattia Ficarelli, Harry Wilson, Rui Pedro Galão, Michela Mazzon, Irati Antzin-Anduetza, Mark Marsh, Stuart JD Neil, Chad M Swanson
Published 2019-07-01

Minimal impact of ZAP on lentiviral vector production and transduction efficiency

by Helin Sertkaya, Laura Hidalgo, Mattia Ficarelli, Dorota Kmiec, Adrian W. Signell, Sadfer Ali, Hannah Parker, Harry Wilson, Stuart J.D. Neil, Michael H. Malim, Conrad A. Vink, Chad M. Swanson
Published 2021-12-01