A Novel Cardenolide Glycoside Isolated from <i>Xysmalobium undulatum</i> Reduces Levels of the Alzheimer’s Disease-Associated β-Amyloid Peptides Aβ42 In Vitro

by Anuradha Thakur, Phanankosi Moyo, Carl Johan van der Westhuizen, Hyun Ok Yang, Vinesh Maharaj
Published 2021-07-01

Natural Products: A Potential Source of Malaria Transmission Blocking Drugs?

by Phanankosi Moyo, Grace Mugumbate, Jacobus N. Eloff, Abraham I. Louw, Vinesh J. Maharaj, Lyn-Marié Birkholtz
Published 2020-09-01

Bioassay-guided isolation and identification of gametocytocidal compounds from Artemisia afra (Asteraceae)

by Phanankosi Moyo, Phaladi Kunyane, Mamoalosi A. Selepe, Jacobus N. Eloff, Jandeli Niemand, Abraham I. Louw, Vinesh J. Maharaj, Lyn-Marie Birkholtz
Published 2019-03-01

Naphthylisoquinoline alkaloids, validated as hit multistage antiplasmodial natural products

by Phanankosi Moyo, William Shamburger, Mariëtte E. van der Watt, Janette Reader, Ana Carolina C. de Sousa, Timothy J. Egan, Vinesh J. Maharaj, Gerhard Bringmann, Lyn-Marie Birkholtz
Published 2020-08-01

Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box

by Janette Reader, Mariëtte E. van der Watt, Dale Taylor, Claire Le Manach, Nimisha Mittal, Sabine Ottilie, Anjo Theron, Phanankosi Moyo, Erica Erlank, Luisa Nardini, Nelius Venter, Sonja Lauterbach, Belinda Bezuidenhout, Andre Horatscheck, Ashleigh van Heerden, Natalie J. Spillman, Anne N. Cowell, Jessica Connacher, Daniel Opperman, Lindsey M. Orchard, Manuel Llinás, Eva S. Istvan, Daniel E. Goldberg, Grant A. Boyle, David Calvo, Dalu Mancama, Theresa L. Coetzer, Elizabeth A. Winzeler, James Duffy, Lizette L. Koekemoer, Gregory Basarab, Kelly Chibale, Lyn-Marié Birkholtz
Published 2021-01-01