H3K36 methylation reprograms gene expression to drive early gametocyte development in Plasmodium falciparum

by Jessica Connacher, Gabrielle A. Josling, Lindsey M. Orchard, Janette Reader, Manuel Llinás, Lyn-Marié Birkholtz
Published 2021-04-01

Transcriptional Profiling Defines Histone Acetylation as a Regulator of Gene Expression during Human-to-Mosquito Transmission of the Malaria Parasite Plasmodium falciparum

by Che J. Ngwa, Meike J. Kiesow, Olga Papst, Lindsey M. Orchard, Michael Filarsky, Alina N. Rosinski, Till S. Voss, Manuel Llinás, Manuel Llinás, Gabriele Pradel
Published 2017-07-01

A seven-helix protein constitutes stress granules crucial for regulating translation during human-to-mosquito transmission of Plasmodium falciparum.

by Sandra Bennink, Andreas von Bohl, Che J Ngwa, Leonie Henschel, Andrea Kuehn, Nicole Pilch, Tim Weißbach, Alina N Rosinski, Matthias Scheuermayer, Urska Repnik, Jude M Przyborski, Allen M Minns, Lindsey M Orchard, Gareth Griffiths, Scott E Lindner, Manuel Llinás, Gabriele Pradel
Published 2018-08-01

Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box

by Janette Reader, Mariëtte E. van der Watt, Dale Taylor, Claire Le Manach, Nimisha Mittal, Sabine Ottilie, Anjo Theron, Phanankosi Moyo, Erica Erlank, Luisa Nardini, Nelius Venter, Sonja Lauterbach, Belinda Bezuidenhout, Andre Horatscheck, Ashleigh van Heerden, Natalie J. Spillman, Anne N. Cowell, Jessica Connacher, Daniel Opperman, Lindsey M. Orchard, Manuel Llinás, Eva S. Istvan, Daniel E. Goldberg, Grant A. Boyle, David Calvo, Dalu Mancama, Theresa L. Coetzer, Elizabeth A. Winzeler, James Duffy, Lizette L. Koekemoer, Gregory Basarab, Kelly Chibale, Lyn-Marié Birkholtz
Published 2021-01-01