Introducing Open Biology

by David Glover, Christine Holt, Louise Johnson, Peter Parham
Published 2011-01-01

Two to Tango: Co-evolution of Hominid Natural Killer Cell Receptors and MHC

by Emily E. Wroblewski, Peter Parham, Lisbeth A. Guethlein
Published 2019-02-01

Computational analyses of an evolutionary arms race between mammalian immunity mediated by immunoglobulin A and its subversion by bacterial pathogens.

by Ana Pinheiro, Jenny M Woof, Laurent Abi-Rached, Peter Parham, Pedro J Esteves
Published 2013-01-01

Human-specific evolution and adaptation led to major qualitative differences in the variable receptors of human and chimpanzee natural killer cells.

by Laurent Abi-Rached, Achim K Moesta, Raja Rajalingam, Lisbeth A Guethlein, Peter Parham
Published 2010-11-01

Race, Ethnicity and Ancestry in Unrelated Transplant Matching for the National Marrow Donor Program: A Comparison of Multiple Forms of Self-Identification with Genetics.

by Jill A Hollenbach, Aliya Saperstein, Mark Albrecht, Cynthia Vierra-Green, Peter Parham, Paul J Norman, Martin Maiers
Published 2015-01-01

Distinguishing functional polymorphism from random variation in the sequences of >10,000 HLA-A, -B and -C alleles.

by James Robinson, Lisbeth A Guethlein, Nezih Cereb, Soo Young Yang, Paul J Norman, Steven G E Marsh, Peter Parham
Published 2017-06-01

Signature Patterns of MHC Diversity in Three Gombe Communities of Wild Chimpanzees Reflect Fitness in Reproduction and Immune Defense against SIVcpz.

by Emily E Wroblewski, Paul J Norman, Lisbeth A Guethlein, Rebecca S Rudicell, Miguel A Ramirez, Yingying Li, Beatrice H Hahn, Anne E Pusey, Peter Parham
Published 2015-05-01

Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population.

by Hugo G Hilton, Paul J Norman, Neda Nemat-Gorgani, Ana Goyos, Jill A Hollenbach, Brenna M Henn, Christopher R Gignoux, Lisbeth A Guethlein, Peter Parham
Published 2015-08-01

KIR Variation in Iranians Combines High Haplotype and Allotype Diversity With an Abundance of Functional Inhibitory Receptors

by Claudia Alicata, Elham Ashouri, Elham Ashouri, Elham Ashouri, Elham Ashouri, Neda Nemat-Gorgani, Neda Nemat-Gorgani, Neda Nemat-Gorgani, Lisbeth A. Guethlein, Lisbeth A. Guethlein, Wesley M. Marin, Sudan Tao, Sudan Tao, Lorenzo Moretta, Jill A. Hollenbach, John Trowsdale, James A. Traherne, Abbas Ghaderi, Peter Parham, Peter Parham, Paul J. Norman, Paul J. Norman, Paul J. Norman
Published 2020-04-01

Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus.

by Chul-Woo Pyo, Lisbeth A Guethlein, Quyen Vu, Ruihan Wang, Laurent Abi-Rached, Paul J Norman, Steven G E Marsh, Jeffrey S Miller, Peter Parham, Daniel E Geraghty
Published 2010-12-01

Significant association of KIR2DL3-HLA-C1 combination with cerebral malaria and implications for co-evolution of KIR and HLA.

by Kouyuki Hirayasu, Jun Ohashi, Koichi Kashiwase, Hathairad Hananantachai, Izumi Naka, Atsuko Ogawa, Minoko Takanashi, Masahiro Satake, Kazunori Nakajima, Peter Parham, Hisashi Arase, Katsushi Tokunaga, Jintana Patarapotikul, Toshio Yabe
Published 2012-01-01

Conservation, Extensive Heterozygosity, and Convergence of Signaling Potential All Indicate a Critical Role for KIR3DL3 in Higher Primates

by Laura A. Leaton, Laura A. Leaton, Jonathan Shortt, Katherine M. Kichula, Katherine M. Kichula, Sudan Tao, Sudan Tao, Sudan Tao, Neda Nemat-Gorgani, Neda Nemat-Gorgani, Alexander J. Mentzer, Stephen J. Oppenheimer, Zhihui Deng, Jill A. Hollenbach, Christopher R. Gignoux, Lisbeth A. Guethlein, Lisbeth A. Guethlein, Peter Parham, Peter Parham, Mary Carrington, Mary Carrington, Paul J. Norman, Paul J. Norman
Published 2019-01-01

Co-evolution of human leukocyte antigen (HLA) class I ligands with killer-cell immunoglobulin-like receptors (KIR) in a genetically diverse population of sub-Saharan Africans.

by Paul J Norman, Jill A Hollenbach, Neda Nemat-Gorgani, Lisbeth A Guethlein, Hugo G Hilton, Marcelo J Pando, Kwadwo A Koram, Eleanor M Riley, Laurent Abi-Rached, Peter Parham
Published 2013-10-01

Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism

by Matteo Fumagalli, Stephane M Camus, Yoan Diekmann, Alice Burke, Marine D Camus, Paul J Norman, Agnel Joseph, Laurent Abi-Rached, Andrea Benazzo, Rita Rasteiro, Iain Mathieson, Maya Topf, Peter Parham, Mark G Thomas, Frances M Brodsky
Published 2019-06-01

HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome

by Patricia T. Illing, Phillip Pymm, Nathan P. Croft, Hugo G. Hilton, Vladimir Jojic, Alex S. Han, Juan L. Mendoza, Nicole A. Mifsud, Nadine L. Dudek, James McCluskey, Peter Parham, Jamie Rossjohn, Julian P. Vivian, Anthony W. Purcell
Published 2018-11-01

Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy

by Oisín Huhn, Martin A. Ivarsson, Lucy Gardner, Mike Hollinshead, Jane C Stinchcombe, Puran Chen, Norman Shreeve, Olympe Chazara, Lydia E. Farrell, Jakob Theorell, Hormas Ghadially, Peter Parham, Gillian Griffiths, Amir Horowitz, Ashley Moffett, Andrew M. Sharkey, Francesco Colucci
Published 2020-01-01

High-Resolution Characterization of KIR Genes in a Large North American Cohort Reveals Novel Details of Structural and Sequence Diversity

by Leonardo M. Amorim, Danillo G. Augusto, Neda Nemat-Gorgani, Gonzalo Montero-Martin, Wesley M. Marin, Hengameh Shams, Ravi Dandekar, Stacy Caillier, Peter Parham, Marcelo A. Fernández-Viña, Jorge R. Oksenberg, Paul J. Norman, Paul J. Norman, Jill A. Hollenbach
Published 2021-05-01

The Intergenic Recombinant HLA-B∗46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands

by Hugo G. Hilton, Curtis P. McMurtrey, Alex S. Han, Zakia Djaoud, Lisbeth A. Guethlein, Jeroen H. Blokhuis, Jason L. Pugh, Ana Goyos, Amir Horowitz, Rico Buchli, Ken W. Jackson, Wilfred Bardet, David A. Bushnell, Philip J. Robinson, Juan L. Mendoza, Michael E. Birnbaum, Morten Nielsen, K. Christopher Garcia, William H. Hildebrand, Peter Parham
Published 2017-05-01

Casting a wider net: Immunosurveillance by nonclassical MHC molecules.

by M Patricia D'Souza, Erin Adams, John D Altman, Michael E Birnbaum, Cesar Boggiano, Giulia Casorati, Yueh-Hsiu Chien, Anthony Conley, Sidonia Barbara Guiomar Eckle, Klaus Früh, Timothy Gondré-Lewis, Namir Hassan, Huang Huang, Lakshmi Jayashankar, Anne G Kasmar, Nina Kunwar, Judith Lavelle, David M Lewinsohn, Branch Moody, Louis Picker, Lakshmi Ramachandra, Nilabh Shastri, Peter Parham, Andrew J McMichael, Jonathan W Yewdell
Published 2019-02-01

Reconstructing the population genetic history of the Caribbean.

by Andrés Moreno-Estrada, Simon Gravel, Fouad Zakharia, Jacob L McCauley, Jake K Byrnes, Christopher R Gignoux, Patricia A Ortiz-Tello, Ricardo J Martínez, Dale J Hedges, Richard W Morris, Celeste Eng, Karla Sandoval, Suehelay Acevedo-Acevedo, Paul J Norman, Zulay Layrisse, Peter Parham, Juan Carlos Martínez-Cruzado, Esteban González Burchard, Michael L Cuccaro, Eden R Martin, Carlos D Bustamante
Published 2013-11-01