Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population.

by Hugo G Hilton, Paul J Norman, Neda Nemat-Gorgani, Ana Goyos, Jill A Hollenbach, Brenna M Henn, Christopher R Gignoux, Lisbeth A Guethlein, Peter Parham
Published 2015-08-01

Co-evolution of human leukocyte antigen (HLA) class I ligands with killer-cell immunoglobulin-like receptors (KIR) in a genetically diverse population of sub-Saharan Africans.

by Paul J Norman, Jill A Hollenbach, Neda Nemat-Gorgani, Lisbeth A Guethlein, Hugo G Hilton, Marcelo J Pando, Kwadwo A Koram, Eleanor M Riley, Laurent Abi-Rached, Peter Parham
Published 2013-10-01

Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian immunity.

by Hugo G Hilton, Nimrod D Rubinstein, Peter Janki, Andrea T Ireland, Nicholas Bernstein, Nicole L Fong, Kevin M Wright, Megan Smith, David Finkle, Baby Martin-McNulty, Margaret Roy, Denise M Imai, Vladimir Jojic, Rochelle Buffenstein
Published 2019-11-01

HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome

by Patricia T. Illing, Phillip Pymm, Nathan P. Croft, Hugo G. Hilton, Vladimir Jojic, Alex S. Han, Juan L. Mendoza, Nicole A. Mifsud, Nadine L. Dudek, James McCluskey, Peter Parham, Jamie Rossjohn, Julian P. Vivian, Anthony W. Purcell
Published 2018-11-01

The Intergenic Recombinant HLA-B∗46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands

by Hugo G. Hilton, Curtis P. McMurtrey, Alex S. Han, Zakia Djaoud, Lisbeth A. Guethlein, Jeroen H. Blokhuis, Jason L. Pugh, Ana Goyos, Amir Horowitz, Rico Buchli, Ken W. Jackson, Wilfred Bardet, David A. Bushnell, Philip J. Robinson, Juan L. Mendoza, Michael E. Birnbaum, Morten Nielsen, K. Christopher Garcia, William H. Hildebrand, Peter Parham
Published 2017-05-01