Current Developments in Detection of Identity-by-Descent Methods and Applications

by Evan L. Sticca, Gillian M. Belbin, Christopher R. Gignoux
Published 2021-09-01

Admixed Populations Improve Power for Variant Discovery and Portability in Genome-Wide Association Studies

by Meng Lin, Danny S. Park, Noah A. Zaitlen, Brenna M. Henn, Christopher R. Gignoux
Published 2021-05-01

Rapid detection of identity-by-descent tracts for mega-scale datasets

by Ruhollah Shemirani, Gillian M. Belbin, Christy L. Avery, Eimear E. Kenny, Christopher R. Gignoux, José Luis Ambite
Published 2021-06-01

Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population.

by Hugo G Hilton, Paul J Norman, Neda Nemat-Gorgani, Ana Goyos, Jill A Hollenbach, Brenna M Henn, Christopher R Gignoux, Lisbeth A Guethlein, Peter Parham
Published 2015-08-01

The Great Migration and African-American Genomic Diversity.

by Soheil Baharian, Maxime Barakatt, Christopher R Gignoux, Suyash Shringarpure, Jacob Errington, William J Blot, Carlos D Bustamante, Eimear E Kenny, Scott M Williams, Melinda C Aldrich, Simon Gravel
Published 2016-05-01

Imputation-Aware Tag SNP Selection To Improve Power for Large-Scale, Multi-ethnic Association Studies

by Genevieve L. Wojcik, Christian Fuchsberger, Daniel Taliun, Ryan Welch, Alicia R Martin, Suyash Shringarpure, Christopher S. Carlson, Goncalo Abecasis, Hyun Min Kang, Michael Boehnke, Carlos D. Bustamante, Christopher R. Gignoux, Eimear E. Kenny
Published 2018-10-01

Admixture mapping in two Mexican samples identifies significant associations of locus ancestry with triglyceride levels in the BUD13/ZNF259/APOA5 region and fine mapping points to...

by Esteban J Parra, Andrew Mazurek, Christopher R Gignoux, Alexandra Sockell, Michael Agostino, Andrew P Morris, Lauren E Petty, Craig L Hanis, Nancy J Cox, Adan Valladares-Salgado, Jennifer E Below, Miguel Cruz
Published 2017-01-01

Population genetic structure and origins of Native Hawaiians in the multiethnic cohort study.

by Sung K Kim, Christopher R Gignoux, Jeffrey D Wall, Annette Lum-Jones, Hansong Wang, Christopher A Haiman, Gary K Chen, Brian E Henderson, Laurence N Kolonel, Loic Le Marchand, Daniel O Stram, Richa Saxena, Iona Cheng
Published 2012-01-01

History shaped the geographic distribution of genomic admixture on the island of Puerto Rico.

by Marc Via, Christopher R Gignoux, Lindsey A Roth, Laura Fejerman, Joshua Galanter, Shweta Choudhry, Gladys Toro-Labrador, Jorge Viera-Vera, Taras K Oleksyk, Kenneth Beckman, Elad Ziv, Neil Risch, Esteban González Burchard, Juan Carlos Martínez-Cruzado
Published 2011-01-01

Genomic Insights into the Ancestry and Demographic History of South America.

by Julian R Homburger, Andrés Moreno-Estrada, Christopher R Gignoux, Dominic Nelson, Elena Sanchez, Patricia Ortiz-Tello, Bernardo A Pons-Estel, Eduardo Acevedo-Vasquez, Pedro Miranda, Carl D Langefeld, Simon Gravel, Marta E Alarcón-Riquelme, Carlos D Bustamante
Published 2015-12-01

On the cross-population generalizability of gene expression prediction models.

by Kevin L Keys, Angel C Y Mak, Marquitta J White, Walter L Eckalbar, Andrew W Dahl, Joel Mefford, Anna V Mikhaylova, María G Contreras, Jennifer R Elhawary, Celeste Eng, Donglei Hu, Scott Huntsman, Sam S Oh, Sandra Salazar, Michael A Lenoir, Jimmie C Ye, Timothy A Thornton, Noah Zaitlen, Esteban G Burchard, Christopher R Gignoux
Published 2020-08-01

Reconstructing Native American migrations from whole-genome and whole-exome data.

by Simon Gravel, Fouad Zakharia, Andres Moreno-Estrada, Jake K Byrnes, Marina Muzzio, Juan L Rodriguez-Flores, Eimear E Kenny, Christopher R Gignoux, Brian K Maples, Wilfried Guiblet, Julie Dutil, Marc Via, Karla Sandoval, Gabriel Bedoya, 1000 Genomes Project, Taras K Oleksyk, Andres Ruiz-Linares, Esteban G Burchard, Juan Carlos Martinez-Cruzado, Carlos D Bustamante
Published 2013-01-01

Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures

by Joshua M Galanter, Christopher R Gignoux, Sam S Oh, Dara Torgerson, Maria Pino-Yanes, Neeta Thakur, Celeste Eng, Donglei Hu, Scott Huntsman, Harold J Farber, Pedro C Avila, Emerita Brigino-Buenaventura, Michael A LeNoir, Kelly Meade, Denise Serebrisky, William Rodríguez-Cintrón, Rajesh Kumar, Jose R Rodríguez-Santana, Max A Seibold, Luisa N Borrell, Esteban G Burchard, Noah Zaitlen
Published 2017-01-01

Genetic ancestry-smoking interactions and lung function in African Americans: a cohort study.

by Melinda C Aldrich, Rajesh Kumar, Laura A Colangelo, L Keoki Williams, Saunak Sen, Stephen B Kritchevsky, Bernd Meibohm, Joshua Galanter, Donglei Hu, Christopher R Gignoux, Yongmei Liu, Tamara B Harris, Elad Ziv, Joseph Zmuda, Melissa Garcia, Tennille S Leak, Marilyn G Foreman, Lewis J Smith, Myriam Fornage, Kiang Liu, Esteban G Burchard, Health ABC and CARDIA Studies Groups
Published 2012-01-01

Heterogeneity in genetic admixture across different regions of Argentina.

by Sergio Avena, Marc Via, Elad Ziv, Eliseo J Pérez-Stable, Christopher R Gignoux, Cristina Dejean, Scott Huntsman, Gabriela Torres-Mejía, Julie Dutil, Jaime L Matta, Kenneth Beckman, Esteban González Burchard, María Laura Parolin, Alicia Goicoechea, Noemí Acreche, Mariel Boquet, María Del Carmen Ríos Part, Vanesa Fernández, Jorge Rey, Mariana C Stern, Raúl F Carnese, Laura Fejerman
Published 2012-01-01

Conservation, Extensive Heterozygosity, and Convergence of Signaling Potential All Indicate a Critical Role for KIR3DL3 in Higher Primates

by Laura A. Leaton, Laura A. Leaton, Jonathan Shortt, Katherine M. Kichula, Katherine M. Kichula, Sudan Tao, Sudan Tao, Sudan Tao, Neda Nemat-Gorgani, Neda Nemat-Gorgani, Alexander J. Mentzer, Stephen J. Oppenheimer, Zhihui Deng, Jill A. Hollenbach, Christopher R. Gignoux, Lisbeth A. Guethlein, Lisbeth A. Guethlein, Peter Parham, Peter Parham, Mary Carrington, Mary Carrington, Paul J. Norman, Paul J. Norman
Published 2019-01-01

Reconstructing the population genetic history of the Caribbean.

by Andrés Moreno-Estrada, Simon Gravel, Fouad Zakharia, Jacob L McCauley, Jake K Byrnes, Christopher R Gignoux, Patricia A Ortiz-Tello, Ricardo J Martínez, Dale J Hedges, Richard W Morris, Celeste Eng, Karla Sandoval, Suehelay Acevedo-Acevedo, Paul J Norman, Zulay Layrisse, Peter Parham, Juan Carlos Martínez-Cruzado, Esteban González Burchard, Michael L Cuccaro, Eden R Martin, Carlos D Bustamante
Published 2013-11-01

Strategies for Enriching Variant Coverage in Candidate Disease Loci on a Multiethnic Genotyping Array.

by Stephanie A Bien, Genevieve L Wojcik, Niha Zubair, Christopher R Gignoux, Alicia R Martin, Jonathan M Kocarnik, Lisa W Martin, Steven Buyske, Jeffrey Haessler, Ryan W Walker, Iona Cheng, Mariaelisa Graff, Lucy Xia, Nora Franceschini, Tara Matise, Regina James, Lucia Hindorff, Loic Le Marchand, Kari E North, Christopher A Haiman, Ulrike Peters, Ruth J F Loos, Charles L Kooperberg, Carlos D Bustamante, Eimear E Kenny, Christopher S Carlson, PAGE Study
Published 2016-01-01

Development of a small panel of SNPs to infer ancestry in Chileans that distinguishes Aymara and Mapuche components

by Ricardo A. Verdugo, Alex Di Genova, Luisa Herrera, Mauricio Moraga, Mónica Acuña, Soledad Berríos, Elena Llop, Carlos Y. Valenzuela, M. Leonor Bustamante, Dayhana Digman, Adriana Symon, Soledad Asenjo, Pamela López, Alejandro Blanco, José Suazo, Emmanuelle Barozet, Fresia Caba, Marcelo Villalón, Sergio Alvarado, Dante Cáceres, Katherine Salgado, Pilar Portales, Andrés Moreno-Estrada, Christopher R. Gignoux, Karla Sandoval, Carlos D. Bustamante, Celeste Eng, Scott Huntsman, Esteban G. Burchard, Nicolás Loira, Alejandro Maass, Lucía Cifuentes
Published 2020-04-01

Genetic identification of a common collagen disease in Puerto Ricans via identity-by-descent mapping in a health system

by Gillian Morven Belbin, Jacqueline Odgis, Elena P Sorokin, Muh-Ching Yee, Sumita Kohli, Benjamin S Glicksberg, Christopher R Gignoux, Genevieve L Wojcik, Tielman Van Vleck, Janina M Jeff, Michael Linderman, Claudia Schurmann, Douglas Ruderfer, Xiaoqiang Cai, Amanda Merkelson, Anne E Justice, Kristin L Young, Misa Graff, Kari E North, Ulrike Peters, Regina James, Lucia Hindorff, Ruth Kornreich, Lisa Edelmann, Omri Gottesman, Eli EA Stahl, Judy H Cho, Ruth JF Loos, Erwin P Bottinger, Girish N Nadkarni, Noura S Abul-Husn, Eimear E Kenny
Published 2017-09-01