Promoter methylation of DNA damage repair (DDR) genes in human tumor entities: RBBP8/CtIP is almost exclusively methylated in bladder cancer

by Jolein Mijnes, Jürgen Veeck, Nadine T. Gaisa, Eduard Burghardt, Tim C. de Ruijter, Sonja Gostek, Edgar Dahl, David Pfister, Sebastian C. Schmid, Ruth Knüchel, Michael Rose
Published 2018-02-01

Parallel PI3K, AKT and mTOR inhibition is required to control feedback loops that limit tumor therapy.

by Anuja Sathe, Géraldine Chalaud, Immanuel Oppolzer, Kit Yeng Wong, Margarita von Busch, Sebastian C Schmid, Zhichao Tong, Margitta Retz, Juergen E Gschwend, Wolfgang A Schulz, Roman Nawroth
Published 2018-01-01

STAT3/5 Inhibitors Suppress Proliferation in Bladder Cancer and Enhance Oncolytic Adenovirus Therapy

by Sruthi V. Hindupur, Sebastian C. Schmid, Jana Annika Koch, Ahmed Youssef, Eva-Maria Baur, Dongbiao Wang, Thomas Horn, Julia Slotta-Huspenina, Juergen E. Gschwend, Per Sonne Holm, Roman Nawroth
Published 2020-02-01

Radiation therapy before radical cystectomy combined with immunotherapy in locally advanced bladder cancer – study protocol of a prospective, single arm, multicenter phase II trial...

by Sebastian C. Schmid, Florestan J. Koll, Claus Rödel, Philipp Maisch, Andreas Sauter, Franziska Beckert, Anna Seitz, Hubert Kübler, Michael Flentje, Felix Chun, Stephanie E. Combs, Kilian Schiller, Jürgen E. Gschwend, Margitta Retz
Published 2020-01-01