Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception

by Roderick C. Slieker, Caroline L. Relton, Tom R. Gaunt, P. Eline Slagboom, Bastiaan T. Heijmans
Published 2018-05-01

Metabolic biomarker profiling for identification of susceptibility to severe pneumonia and COVID-19 in the general population

by Heli Julkunen, Anna Cichońska, P Eline Slagboom, Peter Würtz, Nightingale Health UK Biobank Initiative
Published 2021-05-01

Functional Changes of T-Cell Subsets with Age and CMV Infection

by Fakhri Hassouneh, David Goldeck, Alejandra Pera, Diana van Heemst, P. Eline Slagboom, Graham Pawelec, Rafael Solana
Published 2021-09-01

Association between several clinical and radiological determinants with long-term clinical progression and good prognosis of lower limb osteoarthritis.

by Erlangga Yusuf, Jessica Bijsterbosch, P Eline Slagboom, Herman M Kroon, Frits R Rosendaal, Tom W J Huizinga, Margreet Kloppenburg
Published 2011-01-01

Prenatal famine and genetic variation are independently and additively associated with DNA methylation at regulatory loci within IGF2/H19.

by Elmar W Tobi, P Eline Slagboom, Jenny van Dongen, Dennis Kremer, Aryeh D Stein, Hein Putter, Bastiaan T Heijmans, L H Lumey
Published 2012-01-01

Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child.

by Régine P Steegers-Theunissen, Sylvia A Obermann-Borst, Dennis Kremer, Jan Lindemans, Cissy Siebel, Eric A Steegers, P Eline Slagboom, Bastiaan T Heijmans
Published 2009-11-01

Systematic testing of literature reported genetic variation associated with coronary restenosis: results of the GENDER Study.

by Jeffrey J W Verschuren, Stella Trompet, Iris Postmus, M Lourdes Sampietro, Bastiaan T Heijmans, Jeanine J Houwing-Duistermaat, P Eline Slagboom, J Wouter Jukema
Published 2012-01-01

Correction for both common and rare cell types in blood is important to identify genes that correlate with age

by Damiano Pellegrino-Coppola, Annique Claringbould, Maartje Stutvoet, BIOS Consortium, Dorret I. Boomsma, M. Arfan Ikram, P. Eline Slagboom, Harm-Jan Westra, Lude Franke
Published 2021-03-01

Association of liver enzymes and computed tomography markers of liver steatosis with familial longevity.

by Michiel Sala, Lucia J M Kroft, Boudewijn Röell, Jeroen van der Grond, P Eline Slagboom, Simon P Mooijaart, Albert de Roos, Diana van Heemst
Published 2014-01-01

Epigenetic Variation in Monozygotic Twins: A Genome-Wide Analysis of DNA Methylation in Buccal Cells

by Jenny van Dongen, Erik A. Ehli, Roderick C. Slieker, Meike Bartels, Zachary M. Weber, Gareth E. Davies, P. Eline Slagboom, Bastiaan T. Heijmans, Dorret I. Boomsma
Published 2014-05-01

The Prognostic Value of Metabolic Profiling in Older Patients With a Proximal Femoral Fracture

by Max P.L. van der Sijp, H. Eka D. Suchiman, Monica Eijk, Dina Vojinovic, Arthur H. P. Niggebrugge, Gerard J. Blauw, Wilco P. Achterberg, P. Eline Slagboom
Published 2020-09-01

Lipoprotein particle profiles mark familial and sporadic human longevity.

by Bastiaan T Heijmans, Marian Beekman, Jeanine J Houwing-Duistermaat, Mark R Cobain, Jonathan Powell, Gerard Jan Blauw, Frans van der Ouderaa, Rudi G J Westendorp, P Eline Slagboom
Published 2006-12-01

Small nucleoli are a cellular hallmark of longevity

by Varnesh Tiku, Chirag Jain, Yotam Raz, Shuhei Nakamura, Bree Heestand, Wei Liu, Martin Späth, H. Eka. D. Suchiman, Roman-Ulrich Müller, P. Eline Slagboom, Linda Partridge, Adam Antebi
Published 2017-08-01

Familial longevity is marked by better cognitive performance at middle age: the Leiden Longevity Study.

by Marjon Stijntjes, Anton J M de Craen, Diana van Heemst, Carel G M Meskers, Mark A van Buchem, Rudi G J Westendorp, P Eline Slagboom, Andrea B Maier
Published 2013-01-01

Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait

by Niels van den Berg, Mar Rodríguez-Girondo, Ingrid K. van Dijk, Rick J. Mourits, Kees Mandemakers, Angelique A. P. O. Janssens, Marian Beekman, Ken R. Smith, P. Eline Slagboom
Published 2019-01-01

Pathway analysis using genome-wide association study data for coronary restenosis--a potential role for the PARVB gene.

by Jeffrey J W Verschuren, Stella Trompet, M Lourdes Sampietro, Bastiaan T Heijmans, Werner Koch, Adnan Kastrati, Jeanine J Houwing-Duistermaat, P Eline Slagboom, Paul H A Quax, J Wouter Jukema
Published 2013-01-01

ApoE plasma levels and risk of cardiovascular mortality in old age.

by Simon P Mooijaart, Jimmy F P Berbée, Diana van Heemst, Louis M Havekes, Anton J M de Craen, P Eline Slagboom, Patrick C N Rensen, Rudi G J Westendorp
Published 2006-06-01

PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or noncardiovascular clinical events in an elderly population[S]

by Iris Postmus, Stella Trompet, Anton J.M. de Craen, Brendan M. Buckley, Ian Ford, David J. Stott, Naveed Sattar, P. Eline Slagboom, Rudi G.J. Westendorp, J. Wouter Jukema
Published 2013-02-01

Aberrant Calreticulin Expression in Articular Cartilage of Dio2 Deficient Mice.

by Nils Bomer, Frederique M F Cornelis, Yolande F M Ramos, Wouter den Hollander, Nico Lakenberg, Ruud van der Breggen, Lies Storms, P Eline Slagboom, Rik J U Lories, Ingrid Meulenbelt
Published 2016-01-01

Classification for longevity potential: the use of novel biomarkers

by Marian Beekman, Hae-Won Uh, Diana Van Heemst, Manfred Wuhrer, L. Renee Ruhaak, Vanessa Gonzalez-Covarrubias, Vanessa Gonzalez-Covarrubias, Thomas Hankemeier, Thomas Hankemeier, Jeanine J. Houwing-Duistermaat, P. Eline Slagboom
Published 2016-10-01