Silencing of ANGPTL 3 (angiopoietin-like protein 3) in human hepatocytes results in decreased expression of gluconeogenic genes and reduced triacylglycerol-rich VLDL secretion upon...

by Anna Tikka, Jarkko Soronen, Pirkka‑Pekka Laurila, Jari Metso, Christian Ehnholm, Matti Jauhiainen
Published 2014-12-01

Enhanced vascular permeability facilitates entry of plasma HDL and promotes macrophage-reverse cholesterol transport from skin in mice

by Ilona Kareinen, Lídia Cedó, Reija Silvennoinen, Pirkka-Pekka Laurila, Matti Jauhiainen, Josep Julve, Francisco Blanco-Vaca, Joan Carles Escola-Gil, Petri T. Kovanen, Miriam Lee-Rueckert
Published 2015-02-01

Osbpl8 deficiency in mouse causes an elevation of high-density lipoproteins and gender-specific alterations of lipid metabolism.

by Olivier Béaslas, Jari Metso, Eija Nissilä, Pirkka-Pekka Laurila, Essi Kaiharju, Krishna Chaithanya Batchu, Leena Kaipiainen, Mikko I Mäyränpää, Daoguang Yan, Helena Gylling, Matti Jauhiainen, Vesa M Olkkonen
Published 2013-01-01

USF1 deficiency alleviates inflammation, enhances cholesterol efflux and prevents cholesterol accumulation in macrophages

by Maija Ruuth, Jarkko Soronen, Essi Kaiharju, Krista Merikanto, Julia Perttilä, Jari Metso, Miriam Lee-Rueckert, Marja-Riitta Taskinen, Petri T. Kovanen, Katariina Öörni, Vesa M. Olkkonen, Matti S. Jauhiainen, Pirkka-Pekka Laurila
Published 2018-12-01

Hematopoietic upstream stimulating factor 1 deficiency is associated with increased atherosclerosis susceptibility in LDL receptor knockout mice

by Menno Hoekstra, Baoyan Ren, Pirkka-Pekka Laurila, Reeni B. Hildebrand, Jarkko Soronen, Vanessa Frodermann, Zhuang Li, Mariëtte R. Boon, Janine J. Geerling, Patrick C. N. Rensen, Matti Jauhiainen, Miranda Van Eck
Published 2021-08-01

The Contribution of GWAS Loci in Familial Dyslipidemias.

by Pietari Ripatti, Joel T Rämö, Sanni Söderlund, Ida Surakka, Niina Matikainen, Matti Pirinen, Päivi Pajukanta, Antti-Pekka Sarin, Susan K Service, Pirkka-Pekka Laurila, Christian Ehnholm, Veikko Salomaa, Richard K Wilson, Aarno Palotie, Nelson B Freimer, Marja-Riitta Taskinen, Samuli Ripatti
Published 2016-05-01

Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.

by Michael Inouye, Samuli Ripatti, Johannes Kettunen, Leo-Pekka Lyytikäinen, Niku Oksala, Pirkka-Pekka Laurila, Antti J Kangas, Pasi Soininen, Markku J Savolainen, Jorma Viikari, Mika Kähönen, Markus Perola, Veikko Salomaa, Olli Raitakari, Terho Lehtimäki, Marja-Riitta Taskinen, Marjo-Riitta Järvelin, Mika Ala-Korpela, Aarno Palotie, Paul I W de Bakker
Published 2012-01-01