Identification of novel biomarkers in seasonal allergic rhinitis by combining proteomic, multivariate and pathway analysis.

by Hui Wang, Johan Gottfries, Fredrik Barrenäs, Mikael Benson
Published 2011-01-01

Network properties of complex human disease genes identified through genome-wide association studies.

by Fredrik Barrenas, Sreenivas Chavali, Petter Holme, Reza Mobini, Mikael Benson
Published 2009-01-01

Translating genomic medicine to the clinic: challenges and opportunities

by Huan Zhang, Lars Klareskog, Andreas Matussek, Stefan M. Pfister, Mikael Benson
Published 2019-02-01

Combined multivariate and pathway analyses show that allergen-induced gene expression changes in CD4+ T cells are reversed by glucocorticoids.

by Yelin Zhao, Hui Wang, Mika Gustafsson, Antonella Muraro, Sören Bruhn, Mikael Benson
Published 2012-01-01

Combining network modeling and gene expression microarray analysis to explore the dynamics of Th1 and Th2 cell regulation.

by Marco Pedicini, Fredrik Barrenäs, Trevor Clancy, Filippo Castiglione, Eivind Hovig, Kartiek Kanduri, Daniele Santoni, Mikael Benson
Published 2010-01-01

Meta-Analysis of Expression Profiling Data Indicates Need for Combinatorial Biomarkers in Pediatric Ulcerative Colitis

by Xinxiu Li, Eun Jung Lee, Danuta R. Gawel, Sandra Lilja, Samuel Schäfer, Huan Zhang, Mikael Benson
Published 2020-01-01

An algorithm-based meta-analysis of genome- and proteome-wide data identifies a combination of potential plasma biomarkers for colorectal cancer

by Danuta R. Gawel, Eun Jung Lee, Xinxiu Li, Sandra Lilja, Andreas Matussek, Samuel Schäfer, Renate Slind Olsen, Margaretha Stenmarker, Huan Zhang, Mikael Benson
Published 2019-10-01

Characterization of human thymic exosomes.

by Gabriel Skogberg, Judith Gudmundsdottir, Sjoerd van der Post, Kerstin Sandström, Sören Bruhn, Mikael Benson, Lucia Mincheva-Nilsson, Vladimir Baranov, Esbjörn Telemo, Olov Ekwall
Published 2013-01-01

DNA methylation changes separate allergic patients from healthy controls and may reflect altered CD4+ T-cell population structure.

by Colm E Nestor, Fredrik Barrenäs, Hui Wang, Antonio Lentini, Huan Zhang, Sören Bruhn, Rebecka Jörnsten, Michael A Langston, Gary Rogers, Mika Gustafsson, Mikael Benson
Published 2014-01-01

Dysregulation of complement system and CD4+ T cell activation pathways implicated in allergic response.

by Alexessander Couto Alves, Sören Bruhn, Adaikalavan Ramasamy, Hui Wang, John W Holloway, Anna-Liisa Hartikainen, Marjo-Riitta Jarvelin, Mikael Benson, David J Balding, Lachlan J M Coin
Published 2013-01-01

Potential Involvement of Type I Interferon Signaling in Immunotherapy in Seasonal Allergic Rhinitis

by Lina Mattson, Antonio Lentini, Danuta R. Gawel, Tejaswi V. S. Badam, Mikael Benson, Torbjorn Ledin, Colm E. Nestor, Mika Gustafsson, Jordi Serra-Musach, Janne Bjorkander, Zou Xiang, Huan Zhang
Published 2016-01-01

Estimating heritability and genetic correlations from large health datasets in the absence of genetic data

by Gengjie Jia, Yu Li, Hanxin Zhang, Ishanu Chattopadhyay, Anders Boeck Jensen, David R. Blair, Lea Davis, Peter N. Robinson, Torsten Dahlén, Søren Brunak, Mikael Benson, Gustaf Edgren, Nancy J. Cox, Xin Gao, Andrey Rzhetsky
Published 2019-12-01

5-Hydroxymethylcytosine Remodeling Precedes Lineage Specification during Differentiation of Human CD4+ T Cells

by Colm E. Nestor, Antonio Lentini, Cathrine Hägg Nilsson, Danuta R. Gawel, Mika Gustafsson, Lina Mattson, Hui Wang, Olof Rundquist, Richard R. Meehan, Bernward Klocke, Martin Seifert, Stefanie M. Hauck, Helmut Laumen, Huan Zhang, Mikael Benson
Published 2016-07-01

LASSIM-A network inference toolbox for genome-wide mechanistic modeling.

by Rasmus Magnusson, Guido Pio Mariotti, Mattias Köpsén, William Lövfors, Danuta R Gawel, Rebecka Jörnsten, Jörg Linde, Torbjörn E M Nordling, Elin Nyman, Sylvie Schulze, Colm E Nestor, Huan Zhang, Gunnar Cedersund, Mikael Benson, Andreas Tjärnberg, Mika Gustafsson
Published 2017-06-01

Dynamic Response Genes in CD4+ T Cells Reveal a Network of Interactive Proteins that Classifies Disease Activity in Multiple Sclerosis

by Sandra Hellberg, Daniel Eklund, Danuta R. Gawel, Mattias Köpsén, Huan Zhang, Colm E. Nestor, Ingrid Kockum, Tomas Olsson, Thomas Skogh, Alf Kastbom, Christopher Sjöwall, Magnus Vrethem, Irene Håkansson, Mikael Benson, Maria C. Jenmalm, Mika Gustafsson, Jan Ernerudh
Published 2016-09-01

Digital twins to personalize medicine

by Bergthor Björnsson, Carl Borrebaeck, Nils Elander, Thomas Gasslander, Danuta R. Gawel, Mika Gustafsson, Rebecka Jörnsten, Eun Jung Lee, Xinxiu Li, Sandra Lilja, David Martínez-Enguita, Andreas Matussek, Per Sandström, Samuel Schäfer, Margaretha Stenmarker, X. F. Sun, Oleg Sysoev, Huan Zhang, Mikael Benson, on behalf of the Swedish Digital Twin Consortium
Published 2019-12-01

A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases

by Danuta R. Gawel, Jordi Serra-Musach, Sandra Lilja, Jesper Aagesen, Alex Arenas, Bengt Asking, Malin Bengnér, Janne Björkander, Sophie Biggs, Jan Ernerudh, Henrik Hjortswang, Jan-Erik Karlsson, Mattias Köpsen, Eun Jung Lee, Antonio Lentini, Xinxiu Li, Mattias Magnusson, David Martínez-Enguita, Andreas Matussek, Colm E. Nestor, Samuel Schäfer, Oliver Seifert, Ceylan Sonmez, Henrik Stjernman, Andreas Tjärnberg, Simon Wu, Karin Åkesson, Alex K. Shalek, Margaretha Stenmarker, Huan Zhang, Mika Gustafsson, Mikael Benson
Published 2019-07-01

Correction to: A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases

by Danuta R. Gawel, Jordi Serra-Musach, Sandra Lilja, Jesper Aagesen, Alex Arenas, Bengt Asking, Malin Bengnér, Janne Björkander, Sophie Biggs, Jan Ernerudh, Henrik Hjortswang, Jan-Erik Karlsson, Mattias Köpsen, Eun Jung Lee, Antonio Lentini, Xinxiu Li, Mattias Magnusson, David Martínez-Enguita, Andreas Matussek, Colm E. Nestor, Samuel Schäfer, Oliver Seifert, Ceylan Sonmez, Henrik Stjernman, Andreas Tjärnberg, Simon Wu, Karin Åkesson, Alex K. Shalek, Margaretha Stenmarker, Huan Zhang, Mika Gustafsson, Mikael Benson
Published 2020-04-01

Erratum to: Making sense of big data in health research: towards an EU action plan

by Charles Auffray, Rudi Balling, Inês Barroso, László Bencze, Mikael Benson, Jay Bergeron, Enrique Bernal-Delgado, Niklas Blomberg, Christoph Bock, Ana Conesa, Susanna Del Signore, Christophe Delogne, Peter Devilee, Alberto Di Meglio, Marinus Eijkemans, Paul Flicek, Norbert Graf, Vera Grimm, Henk-Jan Guchelaar, Yi-Ke Guo, Ivo Glynne Gut, Allan Hanbury, Shahid Hanif, Ralf-Dieter Hilgers, Ángel Honrado, D. Rod Hose, Jeanine Houwing-Duistermaat, Tim Hubbard, Sophie Helen Janacek, Haralampos Karanikas, Tim Kievits, Manfred Kohler, Andreas Kremer, Jerry Lanfear, Thomas Lengauer, Edith Maes, Theo Meert, Werner Müller, Dörthe Nickel, Peter Oledzki, Bertrand Pedersen, Milan Petkovic, Konstantinos Pliakos, Magnus Rattray, Josep Redón i Màs, Reinhard Schneider, Thierry Sengstag, Xavier Serra-Picamal, Wouter Spek, Lea A. I. Vaas, Okker van Batenburg, Marc Vandelaer, Peter Varnai, Pablo Villoslada, Juan Antonio Vizcaíno, John Peter Mary Wubbe, Gianluigi Zanetti
Published 2016-11-01