Gene expression prediction by soft integration and the elastic net-best performance of the DREAM3 gene expression challenge.

by Mika Gustafsson, Michael Hörnquist
Published 2010-02-01

Deriving disease modules from the compressed transcriptional space embedded in a deep autoencoder

by Sanjiv K. Dwivedi, Andreas Tjärnberg, Jesper Tegnér, Mika Gustafsson
Published 2020-02-01

ComHub: Community predictions of hubs in gene regulatory networks

by Julia Åkesson, Zelmina Lubovac-Pilav, Rasmus Magnusson, Mika Gustafsson
Published 2021-02-01

Combined multivariate and pathway analyses show that allergen-induced gene expression changes in CD4+ T cells are reversed by glucocorticoids.

by Yelin Zhao, Hui Wang, Mika Gustafsson, Antonella Muraro, Sören Bruhn, Mikael Benson
Published 2012-01-01

Hybrid modelling for stroke care: Review and suggestions of new approaches for risk assessment and simulation of scenarios

by Tilda Herrgårdh, Vince I. Madai, John D. Kelleher, Rasmus Magnusson, Mika Gustafsson, Lili Milani, Peter Gennemark, Gunnar Cedersund
Published 2021-01-01

Progesterone Dampens Immune Responses in In Vitro Activated CD4+ T Cells and Affects Genes Associated With Autoimmune Diseases That Improve During Pregnancy

by Sandra Hellberg, Sandra Hellberg, Johanna Raffetseder, Olof Rundquist, Rasmus Magnusson, Georgia Papapavlou, Maria C. Jenmalm, Jan Ernerudh, Mika Gustafsson
Published 2021-05-01

A validated generally applicable approach using the systematic assessment of disease modules by GWAS reveals a multi-omic module strongly associated with risk factors in multiple s...

by Tejaswi V. S. Badam, Hendrik A. de Weerd, David Martínez-Enguita, Tomas Olsson, Lars Alfredsson, Ingrid Kockum, Maja Jagodic, Zelmina Lubovac-Pilav, Mika Gustafsson
Published 2021-08-01

DNA methylation changes separate allergic patients from healthy controls and may reflect altered CD4+ T-cell population structure.

by Colm E Nestor, Fredrik Barrenäs, Hui Wang, Antonio Lentini, Huan Zhang, Sören Bruhn, Rebecka Jörnsten, Michael A Langston, Gary Rogers, Mika Gustafsson, Mikael Benson
Published 2014-01-01

Potential Involvement of Type I Interferon Signaling in Immunotherapy in Seasonal Allergic Rhinitis

by Lina Mattson, Antonio Lentini, Danuta R. Gawel, Tejaswi V. S. Badam, Mikael Benson, Torbjorn Ledin, Colm E. Nestor, Mika Gustafsson, Jordi Serra-Musach, Janne Bjorkander, Zou Xiang, Huan Zhang
Published 2016-01-01

5-Hydroxymethylcytosine Remodeling Precedes Lineage Specification during Differentiation of Human CD4+ T Cells

by Colm E. Nestor, Antonio Lentini, Cathrine Hägg Nilsson, Danuta R. Gawel, Mika Gustafsson, Lina Mattson, Hui Wang, Olof Rundquist, Richard R. Meehan, Bernward Klocke, Martin Seifert, Stefanie M. Hauck, Helmut Laumen, Huan Zhang, Mikael Benson
Published 2016-07-01

LASSIM-A network inference toolbox for genome-wide mechanistic modeling.

by Rasmus Magnusson, Guido Pio Mariotti, Mattias Köpsén, William Lövfors, Danuta R Gawel, Rebecka Jörnsten, Jörg Linde, Torbjörn E M Nordling, Elin Nyman, Sylvie Schulze, Colm E Nestor, Huan Zhang, Gunnar Cedersund, Mikael Benson, Andreas Tjärnberg, Mika Gustafsson
Published 2017-06-01

Dynamic Response Genes in CD4+ T Cells Reveal a Network of Interactive Proteins that Classifies Disease Activity in Multiple Sclerosis

by Sandra Hellberg, Daniel Eklund, Danuta R. Gawel, Mattias Köpsén, Huan Zhang, Colm E. Nestor, Ingrid Kockum, Tomas Olsson, Thomas Skogh, Alf Kastbom, Christopher Sjöwall, Magnus Vrethem, Irene Håkansson, Mikael Benson, Maria C. Jenmalm, Mika Gustafsson, Jan Ernerudh
Published 2016-09-01

Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes

by Karl E. Carlström, Ewoud Ewing, Mathias Granqvist, Alexandra Gyllenberg, Shahin Aeinehband, Sara Lind Enoksson, Antonio Checa, Tejaswi V. S. Badam, Jesse Huang, David Gomez-Cabrero, Mika Gustafsson, Faiez Al Nimer, Craig E. Wheelock, Ingrid Kockum, Tomas Olsson, Maja Jagodic, Fredrik Piehl
Published 2019-07-01

Digital twins to personalize medicine

by Bergthor Björnsson, Carl Borrebaeck, Nils Elander, Thomas Gasslander, Danuta R. Gawel, Mika Gustafsson, Rebecka Jörnsten, Eun Jung Lee, Xinxiu Li, Sandra Lilja, David Martínez-Enguita, Andreas Matussek, Per Sandström, Samuel Schäfer, Margaretha Stenmarker, X. F. Sun, Oleg Sysoev, Huan Zhang, Mikael Benson, on behalf of the Swedish Digital Twin Consortium
Published 2019-12-01

A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases

by Danuta R. Gawel, Jordi Serra-Musach, Sandra Lilja, Jesper Aagesen, Alex Arenas, Bengt Asking, Malin Bengnér, Janne Björkander, Sophie Biggs, Jan Ernerudh, Henrik Hjortswang, Jan-Erik Karlsson, Mattias Köpsen, Eun Jung Lee, Antonio Lentini, Xinxiu Li, Mattias Magnusson, David Martínez-Enguita, Andreas Matussek, Colm E. Nestor, Samuel Schäfer, Oliver Seifert, Ceylan Sonmez, Henrik Stjernman, Andreas Tjärnberg, Simon Wu, Karin Åkesson, Alex K. Shalek, Margaretha Stenmarker, Huan Zhang, Mika Gustafsson, Mikael Benson
Published 2019-07-01

Correction to: A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases

by Danuta R. Gawel, Jordi Serra-Musach, Sandra Lilja, Jesper Aagesen, Alex Arenas, Bengt Asking, Malin Bengnér, Janne Björkander, Sophie Biggs, Jan Ernerudh, Henrik Hjortswang, Jan-Erik Karlsson, Mattias Köpsen, Eun Jung Lee, Antonio Lentini, Xinxiu Li, Mattias Magnusson, David Martínez-Enguita, Andreas Matussek, Colm E. Nestor, Samuel Schäfer, Oliver Seifert, Ceylan Sonmez, Henrik Stjernman, Andreas Tjärnberg, Simon Wu, Karin Åkesson, Alex K. Shalek, Margaretha Stenmarker, Huan Zhang, Mika Gustafsson, Mikael Benson
Published 2020-04-01