Editorial: Epigenetic Regulation of Innate Immunity

by Menno P. J. de Winther, Tanapat Palaga
Published 2021-06-01

Human monocyte-to-macrophage differentiation involves highly localized gain and loss of DNA methylation at transcription factor binding sites

by Koen F. Dekkers, Annette E. Neele, J. Wouter Jukema, Bastiaan T. Heijmans, Menno P. J. de Winther
Published 2019-06-01

Plant sterol or stanol esters retard lesion formation in LDL receptor-deficient mice independent of changes in serum plant sterols

by Jogchum Plat, Ilona Beugels, Marion J.J. Gijbels, Menno P.J. de Winther, Ronald P. Mensink
Published 2006-12-01

Absence of p55 TNF receptor reduces atherosclerosis, but has no major effect on angiotensin II induced aneurysms in LDL receptor deficient mice.

by Sofia Xanthoulea, Melanie Thelen, Chantal Pöttgens, Marion J J Gijbels, Esther Lutgens, Menno P J de Winther
Published 2009-01-01

Meta-Analysis of in vitro-Differentiated Macrophages Identifies Transcriptomic Signatures That Classify Disease Macrophages in vivo

by Hung-Jen Chen, Andrew Y. F. Li Yim, Andrew Y. F. Li Yim, Guillermo R. Griffith, Wouter J. de Jonge, Marcel M. A. M. Mannens, Enrico Ferrero, Peter Henneman, Menno P. J. de Winther, Menno P. J. de Winther
Published 2019-12-01

Lipopolysaccharide-induced gene expression in murine macrophages is enhanced by prior exposure to oxLDL

by Mathijs Groeneweg, Edwin Kanters, Monique N. Vergouwe, Hilde Duerink, Georg Kraal, Marten H. Hofker, Menno P.J. de Winther
Published 2006-10-01

Selective Targeting of Epigenetic Readers and Histone Deacetylases in Autoimmune and Inflammatory Diseases: Recent Advances and Future Perspectives

by Mohammed Ghiboub, Ahmed M. I. Elfiky, Menno P. J. de Winther, Nicola R. Harker, David F. Tough, Wouter J. de Jonge
Published 2021-04-01

An insect homolog of the vertebrate very low density lipoprotein receptor mediates endocytosis of lipophorins

by Nico P. Dantuma, Marc Potters, Menno P.J. De Winther, Cornelis P. Tensen, Frank P. Kooiman, Jan Bogerd, Dick J. Van der Horst
Published 1999-05-01

Local delivery of polarized macrophages improves reperfusion recovery in a mouse hind limb ischemia model.

by Nadine Jetten, Marjo M P C Donners, Allard Wagenaar, Jack P M Cleutjens, Nico van Rooijen, Menno P J de Winther, Mark J Post
Published 2013-01-01

Effect of human scavenger receptor class A overexpression in bone marrow-derived cells on lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knockout mi...

by Nicole Herijgers, Menno P.J. de Winther, Miranda Van Eck, Louis M. Havekes, Marten H. Hofker, Peter M. Hoogerbrugge, Theo J.C. Van Berkel
Published 2000-09-01

Head-to-Head Comparison of Anti-Inflammatory Performance of Known Natural Products In Vitro.

by Iris E Allijn, Stefan F C Vaessen, Linda C Quarles van Ufford, Kees J Beukelman, Menno P J de Winther, Gert Storm, Raymond M Schiffelers
Published 2016-01-01

Wound administration of M2-polarized macrophages does not improve murine cutaneous healing responses.

by Nadine Jetten, Nadia Roumans, Marion J Gijbels, Andrea Romano, Mark J Post, Menno P J de Winther, Rene R W J van der Hulst, Sofia Xanthoulea
Published 2014-01-01

Macrophage CD40 plays a minor role in obesity-induced metabolic dysfunction.

by Suzanne A B M Aarts, Myrthe E Reiche, Myrthe den Toom, Linda Beckers, Marion J J Gijbels, Norbert Gerdes, Menno P J de Winther, Esther Lutgens
Published 2018-01-01

Myeloid-Specific Acly Deletion Alters Macrophage Phenotype <i>In Vitro</i> and <i>In Vivo</i> without Affecting Tumor Growth

by Kyra E. de Goede, Sanne G. S. Verberk, Jeroen Baardman, Karl J. Harber, Yvette van Kooyk, Menno P. J. de Winther, Sjoerd T. T. Schetters, Jan Van den Bossche
Published 2021-06-01

Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis

by Rosario Luque-Martin, Jan Van den Bossche, Rebecca C. Furze, Annette E. Neele, Saskia van der Velden, Marion J.J. Gijbels, Marion J.J. Gijbels, Cindy P.P.A. van Roomen, Sharon G. Bernard, Wouter J. de Jonge, Inmaculada Rioja, Rab K. Prinjha, Huw D. Lewis, Palwinder K. Mander, Menno P.J. de Winther, Menno P.J. de Winther
Published 2019-10-01

Succinate Is an Inflammation-Induced Immunoregulatory Metabolite in Macrophages

by Karl J. Harber, Kyra E. de Goede, Sanne G. S. Verberk, Elisa Meinster, Helga E. de Vries, Michel van Weeghel, Menno P. J. de Winther, Jan Van den Bossche
Published 2020-09-01

HDAC3 Mediates the Inflammatory Response and LPS Tolerance in Human Monocytes and Macrophages

by Mohammed Ghiboub, Mohammed Ghiboub, Jing Zhao, Andrew Y. F. Li Yim, Andrew Y. F. Li Yim, Ronald Schilderink, Caroline Verseijden, Patricia H. P. van Hamersveld, Jose M. Duarte, Theodorus B. M. Hakvoort, Iris Admiraal, Nicola R. Harker, David F. Tough, Peter Henneman, Menno P. J. de Winther, Menno P. J. de Winther, Wouter J. de Jonge, Wouter J. de Jonge
Published 2020-10-01

Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice

by Kikkie Poels, Mandy M. T. van Leent, Myrthe E. Reiche, Pascal J. H. Kusters, Stephan Huveneers, Menno P. J. de Winther, Willem J. M. Mulder, Esther Lutgens, Tom T. P. Seijkens
Published 2020-08-01

Passive immunization with hypochlorite-oxLDL specific antibodies reduces plaque volume in LDL receptor-deficient mice.

by Marcella van Leeuwen, Michael J Kemna, Menno P J de Winther, Louis Boon, Adriaan M Duijvestijn, Darius Henatsch, Nico A Bos, Marion J J Gijbels, Jan Willem Cohen Tervaert
Published 2013-01-01

Macrophage-specific overexpression of group IIa sPLA2 increases atherosclerosis and enhances collagen deposition

by Stijn A.I. Ghesquiere, Marion J.J. Gijbels, Marit Anthonsen, Patrick J.J. van Gorp, Ingeborg van der Made, Berit Johansen, Marten H. Hofker, Menno P.J. de Winther
Published 2005-02-01