Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception

by Roderick C. Slieker, Caroline L. Relton, Tom R. Gaunt, P. Eline Slagboom, Bastiaan T. Heijmans
Published 2018-05-01

Human monocyte-to-macrophage differentiation involves highly localized gain and loss of DNA methylation at transcription factor binding sites

by Koen F. Dekkers, Annette E. Neele, J. Wouter Jukema, Bastiaan T. Heijmans, Menno P. J. de Winther
Published 2019-06-01

Selective Survival of Embryos Can Explain DNA Methylation Signatures of Adverse Prenatal Environments

by Elmar W. Tobi, Joost van den Heuvel, Bas J. Zwaan, L.H. Lumey, Bastiaan T. Heijmans, Tobias Uller
Published 2018-12-01

Design, measurement and processing of region-specific DNA methylation assays: the mass spectrometry-based method EpiTYPER

by H. Eka D. Suchiman, Roderick C. Slieker, Dennis eKremer, P. Eline eSlagboom, Bastiaan T Heijmans, Elmar Wouter Tobi
Published 2015-09-01

Prenatal famine and genetic variation are independently and additively associated with DNA methylation at regulatory loci within IGF2/H19.

by Elmar W Tobi, P Eline Slagboom, Jenny van Dongen, Dennis Kremer, Aryeh D Stein, Hein Putter, Bastiaan T Heijmans, L H Lumey
Published 2012-01-01

Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child.

by Régine P Steegers-Theunissen, Sylvia A Obermann-Borst, Dennis Kremer, Jan Lindemans, Cissy Siebel, Eric A Steegers, P Eline Slagboom, Bastiaan T Heijmans
Published 2009-11-01

Systematic testing of literature reported genetic variation associated with coronary restenosis: results of the GENDER Study.

by Jeffrey J W Verschuren, Stella Trompet, Iris Postmus, M Lourdes Sampietro, Bastiaan T Heijmans, Jeanine J Houwing-Duistermaat, P Eline Slagboom, J Wouter Jukema
Published 2012-01-01

Epigenetic Variation in Monozygotic Twins: A Genome-Wide Analysis of DNA Methylation in Buccal Cells

by Jenny van Dongen, Erik A. Ehli, Roderick C. Slieker, Meike Bartels, Zachary M. Weber, Gareth E. Davies, P. Eline Slagboom, Bastiaan T. Heijmans, Dorret I. Boomsma
Published 2014-05-01

Respiratory distress syndrome and bronchopulmonary dysplasia after fetal growth restriction: Lessons from a natural experiment in identical twins

by Sophie G. Groene, Jip A. Spekman, Arjan B. te Pas, Bastiaan T. Heijmans, Monique C. Haak, Jeanine M.M. van Klink, Arno A.W. Roest, Enrico Lopriore
Published 2021-02-01

Lipoprotein particle profiles mark familial and sporadic human longevity.

by Bastiaan T Heijmans, Marian Beekman, Jeanine J Houwing-Duistermaat, Mark R Cobain, Jonathan Powell, Gerard Jan Blauw, Frans van der Ouderaa, Rudi G J Westendorp, P Eline Slagboom
Published 2006-12-01

Pathway analysis using genome-wide association study data for coronary restenosis--a potential role for the PARVB gene.

by Jeffrey J W Verschuren, Stella Trompet, M Lourdes Sampietro, Bastiaan T Heijmans, Werner Koch, Adnan Kastrati, Jeanine J Houwing-Duistermaat, P Eline Slagboom, Paul H A Quax, J Wouter Jukema
Published 2013-01-01

Non-homologous end-joining pathway associated with occurrence of myocardial infarction: gene set analysis of genome-wide association study data.

by Jeffrey J W Verschuren, Stella Trompet, Joris Deelen, David J Stott, Naveed Sattar, Brendan M Buckley, Ian Ford, Bastiaan T Heijmans, Henk-Jan Guchelaar, Jeanine J Houwing-Duistermaat, P Eline Slagboom, J Wouter Jukema
Published 2013-01-01

DNA Methylation Landscapes of Human Fetal Development.

by Roderick C Slieker, Matthias S Roost, Liesbeth van Iperen, H Eka D Suchiman, Elmar W Tobi, Françoise Carlotti, Eelco J P de Koning, P Eline Slagboom, Bastiaan T Heijmans, Susana M Chuva de Sousa Lopes
Published 2015-10-01

DNA methylation of IGF2DMR and H19 is associated with fetal and infant growth: the generation R study.

by Marieke I Bouwland-Both, Nina H van Mil, Lisette Stolk, Paul H C Eilers, Michael M P J Verbiest, Bastiaan T Heijmans, Henning Tiemeier, Albert Hofman, Eric A P Steegers, Vincent W V Jaddoe, Régine P M Steegers-Theunissen
Published 2013-01-01

Genome-wide analysis of DNA methylation in buccal cells: a study of monozygotic twins and mQTLs

by Jenny van Dongen, Erik A. Ehli, Rick Jansen, Catharina E. M. van Beijsterveldt, Gonneke Willemsen, Jouke J. Hottenga, Noah A. Kallsen, Shanna A. Peyton, Charles E. Breeze, Cornelis Kluft, Bastiaan T. Heijmans, Meike Bartels, Gareth E. Davies, Dorret I. Boomsma
Published 2018-09-01

DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells

by Matthias S. Roost, Roderick C. Slieker, Monika Bialecka, Liesbeth van Iperen, Maria M. Gomes Fernandes, Nannan He, H. Eka D. Suchiman, Karoly Szuhai, Françoise Carlotti, Eelco J. P. de Koning, Christine L. Mummery, Bastiaan T. Heijmans, Susana M. Chuva de Sousa Lopes
Published 2017-10-01

Markers of endogenous desaturase activity and risk of coronary heart disease in the CAREMA cohort study.

by Yingchang Lu, Anika Vaarhorst, Audrey H H Merry, Martijn E T Dollé, Robert Hovenier, Sandra Imholz, Leo J Schouten, Bastiaan T Heijmans, Michael Müller, P Eline Slagboom, Piet A van den Brandt, Anton P M Gorgels, Jolanda M A Boer, Edith J M Feskens
Published 2012-01-01

RNA-Seq in 296 phased trios provides a high-resolution map of genomic imprinting

by Bharati Jadhav, Ramin Monajemi, Kristina K. Gagalova, Daniel Ho, Harmen H. M. Draisma, Mark A. van de Wiel, Lude Franke, Bastiaan T. Heijmans, Joyce van Meurs, Rick Jansen, GoNL Consortium, BIOS Consortium, Peter A. C. ‘t Hoen, Andrew J. Sharp, Szymon M. Kiełbasa
Published 2019-06-01

Genetic and environmental influences interact with age and sex in shaping the human methylome

by Jenny van Dongen, Michel G. Nivard, Gonneke Willemsen, Jouke-Jan Hottenga, Quinta Helmer, Conor V. Dolan, Erik A. Ehli, Gareth E. Davies, Maarten van Iterson, Charles E. Breeze, Stephan Beck, BIOS Consortium, H. Eka Suchiman, Rick Jansen, Joyce B. van Meurs, Bastiaan T. Heijmans, P. Eline Slagboom, Dorret I. Boomsma
Published 2016-04-01

Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference

by Paul J. Hop, René Luijk, Lucia Daxinger, Maarten van Iterson, Koen F. Dekkers, Rick Jansen, BIOS Consortium, Joyce B. J. van Meurs, Peter A. C. ’t Hoen, M. Arfan Ikram, Marleen M. J. van Greevenbroek, Dorret I. Boomsma, P. Eline Slagboom, Jan H. Veldink, Erik W. van Zwet, Bastiaan T. Heijmans
Published 2020-08-01