Myeloid-Specific Acly Deletion Alters Macrophage Phenotype <i>In Vitro</i> and <i>In Vivo</i> without Affecting Tumor Growth

by Kyra E. de Goede, Sanne G. S. Verberk, Jeroen Baardman, Karl J. Harber, Yvette van Kooyk, Menno P. J. de Winther, Sjoerd T. T. Schetters, Jan Van den Bossche
Published 2021-06-01

Succinate Is an Inflammation-Induced Immunoregulatory Metabolite in Macrophages

by Karl J. Harber, Kyra E. de Goede, Sanne G. S. Verberk, Elisa Meinster, Helga E. de Vries, Michel van Weeghel, Menno P. J. de Winther, Jan Van den Bossche
Published 2020-09-01

Intestinal Macrophages Balance Inflammatory Expression Profiles via Vitamin A and Dectin-1-Mediated Signaling

by Martje N. Erkelens, Gera Goverse, Tanja Konijn, Rosalie Molenaar, Marieke R. Beijer, Jan Van den Bossche, Kyra E. de Goede, Sanne G. S. Verberk, Wouter J. de Jonge, Joke M. M. den Haan, Reina E. Mebius
Published 2020-03-01

Myeloid ATP Citrate Lyase Regulates Macrophage Inflammatory Responses In Vitro Without Altering Inflammatory Disease Outcomes

by Sanne G. S. Verberk, Hendrik J. P. van der Zande, Jeroen Baardman, Kyra E. de Goede, Karl J. Harber, Karl J. Harber, Eelco D. Keuning, Joost M. Lambooij, Frank Otto, Anna Zawistowska-Deniziak, Anna Zawistowska-Deniziak, Helga E. de Vries, Menno P. J. de Winther, Bruno Guigas, Jan Van den Bossche
Published 2021-04-01

A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia

by Jeroen Baardman, Sanne G.S. Verberk, Koen H.M. Prange, Michel van Weeghel, Saskia van der Velden, Dylan G. Ryan, Rob C.I. Wüst, Annette E. Neele, Dave Speijer, Simone W. Denis, Maarten E. Witte, Riekelt H. Houtkooper, Luke A. O’neill, Elena V. Knatko, Albena T. Dinkova-Kostova, Esther Lutgens, Menno P.J. de Winther, Jan Van den Bossche
Published 2018-11-01

Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques

by Jeroen Baardman, Sanne G. S. Verberk, Saskia van der Velden, Marion J. J. Gijbels, Cindy P. P. A. van Roomen, Judith C. Sluimer, Jelle Y. Broos, Guillermo R. Griffith, Koen H. M. Prange, Michel van Weeghel, Soufyan Lakbir, Douwe Molenaar, Elisa Meinster, Annette E. Neele, Gijs Kooij, Helga E. de Vries, Esther Lutgens, Kathryn E. Wellen, Menno P. J. de Winther, Jan Van den Bossche
Published 2020-12-01