A Hypomorphic Dars1D367Y Model Recapitulates Key Aspects of the Leukodystrophy HBSL

by Dominik Fröhlich, Marisa I. Mendes, Andrew J. Kueh, Andrew J. Kueh, Andre Bongers, Marco J. Herold, Marco J. Herold, Gajja S. Salomons, Gary D. Housley, Matthias Klugmann
Published 2021-01-01

Myelodysplasia Syndrome, Clonal Hematopoiesis and Cardiovascular Disease

by Camilla Bertuzzo Veiga, Erin M. Lawrence, Andrew J. Murphy, Marco J. Herold, Dragana Dragoljevic
Published 2021-04-01

MARCH1-mediated ubiquitination of MHC II impacts the MHC I antigen presentation pathway.

by Kayla R Wilson, Haiyin Liu, Geraldine Healey, Vivian Vuong, Satoshi Ishido, Marco J Herold, Jose A Villadangos, Justine D Mintern
Published 2018-01-01

DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice

by Eleonora Ottina, Victor Peperzak, Katia Schoeler, Emma Carrington, Roswitha Sgonc, Marc Pellegrini, Simon Preston, Marco J. Herold, Andreas Strasser, Andreas Villunger
Published 2017-10-01

An Inducible Lentiviral Guide RNA Platform Enables the Identification of Tumor-Essential Genes and Tumor-Promoting Mutations In Vivo

by Brandon J. Aubrey, Gemma L. Kelly, Andrew J. Kueh, Margs S. Brennan, Liam O’Connor, Liz Milla, Stephen Wilcox, Lin Tai, Andreas Strasser, Marco J. Herold
Published 2015-03-01

GM-CSF Quantity Has a Selective Effect on Granulocytic vs. Monocytic Myeloid Development and Function

by Li Sun, Jai Rautela, Jai Rautela, Rebecca B. Delconte, Rebecca B. Delconte, Fernando Souza-Fonseca-Guimaraes, Fernando Souza-Fonseca-Guimaraes, Emma M. Carrington, Emma M. Carrington, Robyn L. Schenk, Robyn L. Schenk, Marco J. Herold, Marco J. Herold, Nicholas D. Huntington, Nicholas D. Huntington, Andrew M. Lew, Andrew M. Lew, Andrew M. Lew, Yuekang Xu, Yifan Zhan, Yifan Zhan, Yifan Zhan
Published 2018-08-01

Therapeutic Response to Non-genotoxic Activation of p53 by Nutlin3a Is Driven by PUMA-Mediated Apoptosis in Lymphoma Cells

by Liz J. Valente, Brandon J. Aubrey, Marco J. Herold, Gemma L. Kelly, Lina Happo, Clare L. Scott, Andrea Newbold, Ricky W. Johnstone, David C.S. Huang, Lyubomir T. Vassilev, Andreas Strasser
Published 2016-03-01

The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation

by Swarna L. Vijayaraj, Rebecca Feltham, Maryam Rashidi, Daniel Frank, Zhengyang Liu, Daniel S. Simpson, Gregor Ebert, Angelina Vince, Marco J. Herold, Andrew Kueh, Jaclyn S. Pearson, Laura F. Dagley, James M. Murphy, Andrew I. Webb, Kate E. Lawlor, James E. Vince
Published 2021-05-01

Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins

by Stephanie Trezise, Alexander Karnowski, Pasquale L. Fedele, Sridurga Mithraprabhu, Yang Liao, Kathy D’Costa, Andrew J. Kueh, Matthew P. Hardy, Catherine M. Owczarek, Marco J. Herold, Andrew Spencer, Wei Shi, Simon N. Willis, Stephen L. Nutt, Lynn M. Corcoran
Published 2018-07-01

Single-Cell Transcriptomics Identifies the Adaptation of Scart1+ Vγ6+ T Cells to Skin Residency as Activated Effector Cells

by Likai Tan, Inga Sandrock, Ivan Odak, Yuval Aizenbud, Anneke Wilharm, Joana Barros-Martins, Yaara Tabib, Alina Borchers, Tiago Amado, Lahiru Gangoda, Marco J. Herold, Marc Schmidt-Supprian, Jan Kisielow, Bruno Silva-Santos, Christian Koenecke, Avi-Hai Hovav, Christian Krebs, Immo Prinz, Sarina Ravens
Published 2019-06-01

Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer

by Stephanie Berger, Erik Procko, Daciana Margineantu, Erinna F Lee, Betty W Shen, Alex Zelter, Daniel-Adriano Silva, Kusum Chawla, Marco J Herold, Jean-Marc Garnier, Richard Johnson, Michael J MacCoss, Guillaume Lessene, Trisha N Davis, Patrick S Stayton, Barry L Stoddard, W Douglas Fairlie, David M Hockenbery, David Baker
Published 2016-11-01

Correction to: PRMT1-mediated H4R3me2a recruits SMARCA4 to promote colorectal cancer progression by enhancing EGFR signaling

by Bing Yao, Tao Gui, Xiangwei Zeng, Yexuan Deng, Zhi Wang, Ying Wang, Dongjun Yang, Qixiang Li, Peipei Xu, Ruifeng Hu, Xinyu Li, Bing Chen, Jin Wang, Ke Zen, Haitao Li, Melissa J. Davis, Marco J. Herold, Hua-Feng Pan, Zhi-Wei Jiang, David C. S. Huang, Ming Liu, Junyi Ju, Quan Zhao
Published 2021-10-01

PRMT1-mediated H4R3me2a recruits SMARCA4 to promote colorectal cancer progression by enhancing EGFR signaling

by Bing Yao, Tao Gui, Xiangwei Zeng, Yexuan Deng, Zhi Wang, Ying Wang, Dongjun Yang, Qixiang Li, Peipei Xu, Ruifeng Hu, Xinyu Li, Bing Chen, Jin Wang, Ke Zen, Haitao Li, Melissa J. Davis, Marco J. Herold, Hua-Feng Pan, Zhi-Wei Jiang, David C. S. Huang, Ming Liu, Junyi Ju, Quan Zhao
Published 2021-04-01

Loss of p53 Causes Stochastic Aberrant X-Chromosome Inactivation and Female-Specific Neural Tube Defects

by Alex R.D. Delbridge, Andrew J. Kueh, Francine Ke, Natasha M. Zamudio, Farrah El-Saafin, Natasha Jansz, Gao-Yuan Wang, Megan Iminitoff, Tamara Beck, Sue Haupt, Yifang Hu, Rose E. May, Lachlan Whitehead, Lin Tai, William Chiang, Marco J. Herold, Ygal Haupt, Gordon K. Smyth, Tim Thomas, Marnie E. Blewitt, Andreas Strasser, Anne K. Voss
Published 2019-04-01

VDAC2 enables BAX to mediate apoptosis and limit tumor development

by Hui San Chin, Mark X. Li, Iris K. L. Tan, Robert L. Ninnis, Boris Reljic, Kristen Scicluna, Laura F. Dagley, Jarrod J. Sandow, Gemma L. Kelly, Andre L. Samson, Stephane Chappaz, Seong L. Khaw, Catherine Chang, Andrew Morokoff, Kerstin Brinkmann, Andrew Webb, Colin Hockings, Cathrine M. Hall, Andrew J. Kueh, Michael T. Ryan, Ruth M. Kluck, Philippe Bouillet, Marco J. Herold, Daniel H. D. Gray, David C. S. Huang, Mark F. van Delft, Grant Dewson
Published 2018-11-01

A point mutation in the Ncr1 signal peptide impairs the development of innate lymphoid cell subsets

by Francisca F. Almeida, Sara Tognarelli, Antoine Marçais, Andrew J. Kueh, Miriam E. Friede, Yang Liao, Simon N. Willis, Kylie Luong, Fabrice Faure, Francois E. Mercier, Justine Galluso, Matthew Firth, Emilie Narni-Mancinelli, Bushra Rais, David T. Scadden, Francesco Spallotta, Sandra Weil, Ariane Giannattasio, Franziska Kalensee, Tobias Zöller, Nicholas D. Huntington, Ulrike Schleicher, Andreas G. Chiocchetti, Sophie Ugolini, Marco J. Herold, Wei Shi, Joachim Koch, Alexander Steinle, Eric Vivier, Thierry Walzer, Gabrielle T. Belz, Evelyn Ullrich
Published 2018-10-01

An Erg-driven transcriptional program controls B cell lymphopoiesis

by Ashley P. Ng, Hannah D. Coughlan, Soroor Hediyeh-zadeh, Kira Behrens, Timothy M. Johanson, Michael Sze Yuan Low, Charles C. Bell, Omer Gilan, Yih-Chih Chan, Andrew J. Kueh, Thomas Boudier, Rebecca Feltham, Anna Gabrielyan, Ladina DiRago, Craig D. Hyland, Helen Ierino, Sandra Mifsud, Elizabeth Viney, Tracy Willson, Mark A. Dawson, Rhys S. Allan, Marco J. Herold, Kelly Rogers, David M. Tarlinton, Gordon K. Smyth, Melissa J. Davis, Stephen L. Nutt, Warren S. Alexander
Published 2020-06-01