Post-translational control of RIPK3 and MLKL mediated necroptotic cell death [version 1; referees: 4 approved]

by James M. Murphy, James E. Vince
Published 2015-11-01

Oxidative Stress and NLRP3-Inflammasome Activity as Significant Drivers of Diabetic Cardiovascular Complications: Therapeutic Implications

by Arpeeta Sharma, Mitchel Tate, Geetha Mathew, James E. Vince, James E. Vince, Rebecca H. Ritchie, Judy B. de Haan
Published 2018-02-01

Deletion of IKK2 in haematopoietic cells of adult mice leads to elevated interleukin-6, neutrophilia and fatal gastrointestinal inflammation

by Karla C. Fischer, Carmel P. Daunt, Cédric S. Tremblay, Sheila Dias, James E. Vince, Anissa M. Jabbour
Published 2021-01-01

Cycloheximide Can Induce Bax/Bak Dependent Myeloid Cell Death Independently of Multiple BH3-Only Proteins.

by Katharine J Goodall, Megan L Finch-Edmondson, Joanne van Vuuren, George C Yeoh, Ian E Gentle, James E Vince, Paul G Ekert, David L Vaux, Bernard A Callus
Published 2016-01-01

Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma

by Sarah A. Best, Sheryl Ding, Ariena Kersbergen, Xueyi Dong, Ji-Ying Song, Yi Xie, Boris Reljic, Kaiming Li, James E. Vince, Vivek Rathi, Gavin M. Wright, Matthew E. Ritchie, Kate D. Sutherland
Published 2019-09-01

The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation

by Swarna L. Vijayaraj, Rebecca Feltham, Maryam Rashidi, Daniel Frank, Zhengyang Liu, Daniel S. Simpson, Gregor Ebert, Angelina Vince, Marco J. Herold, Andrew Kueh, Jaclyn S. Pearson, Laura F. Dagley, James M. Murphy, Andrew I. Webb, Kate E. Lawlor, James E. Vince
Published 2021-05-01

XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation

by Kate E. Lawlor, Rebecca Feltham, Monica Yabal, Stephanie A. Conos, Kaiwen W. Chen, Stephanie Ziehe, Carina Graß, Yifan Zhan, Tan A. Nguyen, Cathrine Hall, Angelina J. Vince, Simon M. Chatfield, Damian B. D’Silva, Kenneth C. Pang, Kate Schroder, John Silke, David L. Vaux, Philipp J. Jost, James E. Vince
Published 2017-07-01