The design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene drive.

by Yuk-Sang Chan, Ryo Takeuchi, Jordan Jarjour, David S Huen, Barry L Stoddard, Steven Russell
Published 2013-01-01

Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome

by Kevin J Forsberg, Ishan V Bhatt, Danica T Schmidtke, Kamyab Javanmardi, Kaylee E Dillard, Barry L Stoddard, Ilya J Finkelstein, Brett K Kaiser, Harmit S Malik
Published 2019-09-01

Precise assembly of complex beta sheet topologies from de novo designed building blocks

by Indigo Chris King, James Gleixner, Lindsey Doyle, Alexandre Kuzin, John F Hunt, Rong Xiao, Gaetano T Montelione, Barry L Stoddard, Frank DiMaio, David Baker
Published 2015-12-01

Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer

by Stephanie Berger, Erik Procko, Daciana Margineantu, Erinna F Lee, Betty W Shen, Alex Zelter, Daniel-Adriano Silva, Kusum Chawla, Marco J Herold, Jean-Marc Garnier, Richard Johnson, Michael J MacCoss, Guillaume Lessene, Trisha N Davis, Patrick S Stayton, Barry L Stoddard, W Douglas Fairlie, David M Hockenbery, David Baker
Published 2016-11-01

Incorporation of sensing modalities into de novo designed fluorescence-activating proteins

by Jason C. Klima, Lindsey A. Doyle, Justin Daho Lee, Michael Rappleye, Lauren A. Gagnon, Min Yen Lee, Emilia P. Barros, Anastassia A. Vorobieva, Jiayi Dou, Samantha Bremner, Jacob S. Quon, Cameron M. Chow, Lauren Carter, David L. Mack, Rommie E. Amaro, Joshua C. Vaughan, Andre Berndt, Barry L. Stoddard, David Baker
Published 2021-02-01