Bioengineering Liver Transplantation

by Monique M.A. Verstegen, Bart Spee, Luc J.W. van der Laan
Published 2019-10-01

Evaluation of RNA isolation methods for microRNA quantification in a range of clinical biofluids

by Henk P. Roest, Jan N. M. IJzermans, Luc J. W. van der Laan
Published 2021-08-01

Cellular and Molecular Mechanisms of Mesenchymal Stem Cell Actions

by Bruno Christ, Marcella Franquesa, Mustapha Najimi, Luc J. W. van der Laan, Marc Hendrik Dahlke
Published 2017-01-01

Detailed kinetics of the direct allo-response in human liver transplant recipients: new insights from an optimized assay.

by Ozlem Tapirdamaz, Shanta Mancham, Luc J W van der Laan, Geert Kazemier, Kris Thielemans, Herold J Metselaar, Jaap Kwekkeboom
Published 2010-01-01

Recreating Tumour Complexity in a Dish: Organoid Models to Study Liver Cancer Cells and their Extracellular Environment

by Gilles S. van Tienderen, Bas Groot Koerkamp, Jan N.M. IJzermans, Luc J.W. van der Laan, Monique M.A. Verstegen
Published 2019-11-01

Association of circulating microRNA‐122 and microRNA‐29a with stage of fibrosis and progression of chronic hepatitis in Labrador Retrievers

by Manabu Sakai, Bart Spee, Guy C. M. Grinwis, Louis C. Penning, Monique E. vanWolferen, Luc J. W. van derLaan, Hille Fieten
Published 2019-01-01

T Follicular Helper Cells As a New Target for Immunosuppressive Therapies

by Lin Yan, Lin Yan, Kitty de Leur, Kitty de Leur, Rudi W. Hendriks, Luc J. W. van der Laan, Yunying Shi, Lanlan Wang, Carla C. Baan
Published 2017-11-01

Rotavirus Infection and Cytopathogenesis in Human Biliary Organoids Potentially Recapitulate Biliary Atresia Development

by Sunrui Chen, Pengfei Li, Yining Wang, Yuebang Yin, Petra E. de Ruiter, Monique M. A. Verstegen, Maikel P. Peppelenbosch, Luc J. W. van der Laan, Qiuwei Pan
Published 2020-08-01

Characterization of Antigen-Presenting Cell Subsets in Human Liver-Draining Lymph Nodes

by Patrick P. C. Boor, Brenda M. Bosma, Khe T. C. Tran, Luc J. W. van der Laan, Hanneke Hagenaars, Jan N. M. IJzermans, Herold J. Metselaar, Jaap Kwekkeboom
Published 2019-03-01

Human Bile Contains Cholangiocyte Organoid-Initiating Cells Which Expand as Functional Cholangiocytes in Non-canonical Wnt Stimulating Conditions

by Floris J. M. Roos, Monique M. A. Verstegen, Laura Muñoz Albarinos, Henk P. Roest, Jan-Werner Poley, Geert W. M. Tetteroo, Jan N. M. IJzermans, Luc J. W. van der Laan
Published 2021-02-01

Characterization of gut-homing molecules in non-endstage livers of patients with primary sclerosing cholangitis and inflammatory bowel disease

by Manon de Krijger, Thijmen Visseren, Manon E. Wildenberg, Gerrit K.J. Hooijer, Monique M.A. Verstegen, Luc J.W. van der Laan, Wouter J. de Jonge, Joanne Verheij, Cyriel Y. Ponsioen
Published 2020-01-01

Mesenchymal Stromal Cell-Derived Factors Promote Tissue Repair in a Small-for-Size Ischemic Liver Model but Do Not Protect against Early Effects of Ischemia and Reperfusion Injury

by Suomi M. G. Fouraschen, Joshua H. Wolf, Luc J. W. van der Laan, Petra E. de Ruiter, Wayne W. Hancock, Job P. van Kooten, Monique M. A. Verstegen, Kim M. Olthoff, Jeroen de Jonge
Published 2015-01-01

Long-term live imaging and multiscale analysis identify heterogeneity and core principles of epithelial organoid morphogenesis

by Lotta Hof, Till Moreth, Michael Koch, Tim Liebisch, Marina Kurtz, Julia Tarnick, Susanna M. Lissek, Monique M. A. Verstegen, Luc J. W. van der Laan, Meritxell Huch, Franziska Matthäus, Ernst H. K. Stelzer, Francesco Pampaloni
Published 2021-02-01

Mitochondrial Fusion Via OPA1 and MFN1 Supports Liver Tumor Cell Metabolism and Growth

by Meng Li, Ling Wang, Yijin Wang, Shaoshi Zhang, Guoying Zhou, Ruby Lieshout, Buyun Ma, Jiaye Liu, Changbo Qu, Monique M. A. Verstegen, Dave Sprengers, Jaap Kwekkeboom, Luc J. W. van der Laan, Wanlu Cao, Maikel P. Peppelenbosch, Qiuwei Pan
Published 2020-01-01

Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells

by Nesrin Tüysüz, Louis van Bloois, Stieneke van den Brink, Harry Begthel, Monique M. A. Verstegen, Luis J. Cruz, Lijian Hui, Luc J. W. van der Laan, Jeroen de Jonge, Robert Vries, Eric Braakman, Enrico Mastrobattista, Jan J. Cornelissen, Hans Clevers, Derk ten Berge
Published 2017-03-01

Prime editing for functional repair in patient-derived disease models

by Imre F. Schene, Indi P. Joore, Rurika Oka, Michal Mokry, Anke H. M. van Vugt, Ruben van Boxtel, Hubert P. J. van der Doef, Luc J. W. van der Laan, Monique M. A. Verstegen, Peter M. van Hasselt, Edward E. S. Nieuwenhuis, Sabine A. Fuchs
Published 2020-10-01

LGR5 marks targetable tumor-initiating cells in mouse liver cancer

by Wanlu Cao, Meng Li, Jiaye Liu, Shaoshi Zhang, Lisanne Noordam, Monique M. A. Verstegen, Ling Wang, Buyun Ma, Shan Li, Wenshi Wang, Michiel Bolkestein, Michael Doukas, Kan Chen, Zhongren Ma, Marco Bruno, Dave Sprengers, Jaap Kwekkeboom, Luc J. W. van der Laan, Ron Smits, Maikel P. Peppelenbosch, Qiuwei Pan
Published 2020-04-01

HOXA13 in etiology and oncogenic potential of Barrett’s esophagus

by Vincent T. Janmaat, Kateryna Nesteruk, Manon C. W. Spaander, Auke P. Verhaar, Bingting Yu, Rodrigo A. Silva, Wayne A. Phillips, Marcin Magierowski, Anouk van de Winkel, H. Scott Stadler, Tatiana Sandoval-Guzmán, Luc J. W. van der Laan, Ernst J. Kuipers, Ron Smits, Marco J. Bruno, Gwenny M. Fuhler, Nicholas J. Clemons, Maikel P. Peppelenbosch
Published 2021-06-01

Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis

by Hedwig S. Kruitwagen, Loes A. Oosterhoff, Ingrid G.W.H. Vernooij, Ingrid M. Schrall, Monique E. van Wolferen, Farah Bannink, Camille Roesch, Lisa van Uden, Martijn R. Molenaar, J. Bernd Helms, Guy C.M. Grinwis, Monique M.A. Verstegen, Luc J.W. van der Laan, Meritxell Huch, Niels Geijsen, Robert G. Vries, Hans Clevers, Jan Rothuizen, Baukje A. Schotanus, Louis C. Penning, Bart Spee
Published 2017-04-01

Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease

by Monique M. A. Verstegen, Floris J. M. Roos, Ksenia Burka, Helmuth Gehart, Myrthe Jager, Maaike de Wolf, Marcel J. C. Bijvelds, Hugo R. de Jonge, Arif I. Ardisasmita, Nick A. van Huizen, Henk P. Roest, Jeroen de Jonge, Michael Koch, Francesco Pampaloni, Sabine A. Fuchs, Imre F. Schene, Theo M. Luider, Hubert P. J. van der Doef, Frank A. J. A. Bodewes, Ruben H. J. de Kleine, Bart Spee, Gert-Jan Kremers, Hans Clevers, Jan N. M. IJzermans, Edwin Cuppen, Luc J. W. van der Laan
Published 2020-12-01