Wnt/β-Catenin Signaling in Liver Cancers

by Wenhui Wang, Ron Smits, Haiping Hao, Chaoyong He
Published 2019-07-01

A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis.

by Claudia Gaspar, Patrick Franken, Lia Molenaar, Cor Breukel, Martin van der Valk, Ron Smits, Riccardo Fodde
Published 2009-07-01

Cancer stemness in Apc- vs. Apc/KRAS-driven intestinal tumorigenesis.

by Mehrnaz Ghazvini, Petra Sonneveld, Andreas Kremer, Patrick Franken, Andrea Sacchetti, Yaser Atlasi, Sabrina Roth, Rosalie Joosten, Ron Smits, Riccardo Fodde
Published 2013-01-01

Activated Signaling Pathways and Targeted Therapies in Desmoid-Type Fibromatosis: A Literature Review

by Milea J. M. Timbergen, Milea J. M. Timbergen, Ron Smits, Dirk J. Grünhagen, Cornelis Verhoef, Stefan Sleijfer, Erik A. C. Wiemer
Published 2019-05-01

Mitochondrial ROS Production Protects the Intestine from Inflammation through Functional M2 Macrophage Polarization

by Laura Formentini, Fulvio Santacatterina, Cristina Núñez de Arenas, Konstantinos Stamatakis, David López-Martínez, Angela Logan, Manuel Fresno, Ron Smits, Michael P. Murphy, José M. Cuezva
Published 2017-05-01

Evaluation of AXIN1 and AXIN2 as targets of tankyrase inhibition in hepatocellular carcinoma cell lines

by Wenhui Wang, Pengyu Liu, Marla Lavrijsen, Shan Li, Ruyi Zhang, Shanshan Li, Wesley S. van de Geer, Harmen J. G. van de Werken, Maikel P. Peppelenbosch, Ron Smits
Published 2021-04-01

Differentially Methylated Regions in Desmoid-Type Fibromatosis: A Comparison Between CTNNB1 S45F and T41A Tumors

by Milea J. M. Timbergen, Milea J. M. Timbergen, Ruben Boers, Anne L. M. Vriends, Joachim Boers, Wilfred F. J. van IJcken, Marla Lavrijsen, Dirk J. Grünhagen, Cornelis Verhoef, Stefan Sleijfer, Ron Smits, Joost Gribnau, Erik A. C. Wiemer
Published 2020-10-01

Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron

by Nils O Lindström, Melanie L Lawrence, Sally F Burn, Jeanette A Johansson, Elvira RM Bakker, Rachel A Ridgway, C-Hong Chang, Michele J Karolak, Leif Oxburgh, Denis J Headon, Owen J Sansom, Ron Smits, Jamie A Davies, Peter Hohenstein
Published 2015-02-01

LGR5 marks targetable tumor-initiating cells in mouse liver cancer

by Wanlu Cao, Meng Li, Jiaye Liu, Shaoshi Zhang, Lisanne Noordam, Monique M. A. Verstegen, Ling Wang, Buyun Ma, Shan Li, Wenshi Wang, Michiel Bolkestein, Michael Doukas, Kan Chen, Zhongren Ma, Marco Bruno, Dave Sprengers, Jaap Kwekkeboom, Luc J. W. van der Laan, Ron Smits, Maikel P. Peppelenbosch, Qiuwei Pan
Published 2020-04-01

HOXA13 in etiology and oncogenic potential of Barrett’s esophagus

by Vincent T. Janmaat, Kateryna Nesteruk, Manon C. W. Spaander, Auke P. Verhaar, Bingting Yu, Rodrigo A. Silva, Wayne A. Phillips, Marcin Magierowski, Anouk van de Winkel, H. Scott Stadler, Tatiana Sandoval-Guzmán, Luc J. W. van der Laan, Ernst J. Kuipers, Ron Smits, Marco J. Bruno, Gwenny M. Fuhler, Nicholas J. Clemons, Maikel P. Peppelenbosch
Published 2021-06-01