Polymorphism in the retinoic acid metabolizing enzyme CYP26B1 and the development of Crohn's Disease.

by Karin Fransén, Petra Franzén, Anders Magnuson, Ali Ateia Elmabsout, Nils Nyhlin, Anna Wickbom, Bengt Curman, Leif Törkvist, Mauro D'Amato, Johan Bohr, Curt Tysk, Allan Sirsjö, Jonas Halfvarson
Published 2013-01-01

Functional Analyses of the Crohn's Disease Risk Gene LACC1.

by Ghazaleh Assadi, Liselotte Vesterlund, Ferdinando Bonfiglio, Luca Mazzurana, Lina Cordeddu, Danika Schepis, Jenny Mjösberg, Sabrina Ruhrmann, Alessia Fabbri, Vladana Vukojevic, Piergiorgio Percipalle, Florian A Salomons, Jurga Laurencikiene, Leif Törkvist, Jonas Halfvarson, Mauro D'Amato
Published 2016-01-01

Multiple polymorphisms affect expression and function of the neuropeptide S receptor (NPSR1).

by Francesca Anedda, Marco Zucchelli, Danika Schepis, Anna Hellquist, Lucia Corrado, Sandra D'Alfonso, Adnane Achour, Gerald McInerney, Alejandro Bertorello, Mikael Lördal, Ragnar Befrits, Jan Björk, Francesca Bresso, Leif Törkvist, Jonas Halfvarson, Juha Kere, Mauro D'Amato
Published 2011-01-01

Analysis of germline GLI1 variation implicates hedgehog signalling in the regulation of intestinal inflammatory pathways.

by Charlie W Lees, William J Zacharias, Mark Tremelling, Colin L Noble, Elaine R Nimmo, Albert Tenesa, Jennine Cornelius, Leif Torkvist, John Kao, Susan Farrington, Hazel E Drummond, Gwo-Tzer Ho, Ian D R Arnott, Henry D Appelman, Lauri Diehl, Harry Campbell, Malcolm G Dunlop, Miles Parkes, Sarah E M Howie, Deborah L Gumucio, Jack Satsangi
Published 2008-12-01

Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis.

by Mélissa Beaudoin, Philippe Goyette, Gabrielle Boucher, Ken Sin Lo, Manuel A Rivas, Christine Stevens, Azadeh Alikashani, Martin Ladouceur, David Ellinghaus, Leif Törkvist, Gautam Goel, Caroline Lagacé, Vito Annese, Alain Bitton, Jakob Begun, Steve R Brant, Francesca Bresso, Judy H Cho, Richard H Duerr, Jonas Halfvarson, Dermot P B McGovern, Graham Radford-Smith, Stefan Schreiber, Philip L Schumm, Yashoda Sharma, Mark S Silverberg, Rinse K Weersma, Quebec IBD Genetics Consortium, NIDDK IBD Genetics Consortium, International IBD Genetics Consortium, Mauro D'Amato, Severine Vermeire, Andre Franke, Guillaume Lettre, Ramnik J Xavier, Mark J Daly, John D Rioux
Published 2013-01-01