Dysregulation of human beta-defensin-2 protein in inflammatory bowel disease.

by Marian C Aldhous, Colin L Noble, Jack Satsangi
Published 2009-07-01

Precision medicine in inflammatory bowel disease: concept, progress and challenges [version 1; peer review: 2 approved]

by Simon P. Borg-Bartolo, Ray Kiran Boyapati, Jack Satsangi, Rahul Kalla
Published 2020-01-01

Inflammatory Bowel Disease: Progress Towards a Gene

by David A van Heel, Jack Satsangi, Alisoun H Carey, Derek P Jewell
Published 2000-01-01

A randomised, double-blind, parallel-group trial to assess mercaptopurine versus placebo to prevent or delay recurrence of Crohn’s disease following surgical resection (TOPPIC)

by Jack Satsangi, Nicholas A Kennedy, Craig Mowat, Ian Arnott, Catriona Keerie, Steff Lewis, Holly Ennis
Published 2017-09-01

The type III intermediate filament vimentin regulates organelle distribution and modulates autophagy.

by Olga Biskou, Victor Casanova, Kirsty M Hooper, Sadie Kemp, Graham P Wright, Jack Satsangi, Peter G Barlow, Craig Stevens
Published 2019-01-01

Cigarette smoke extract (CSE) delays NOD2 expression and affects NOD2/RIPK2 interactions in intestinal epithelial cells.

by Marian C Aldhous, Kimberley Soo, Lesley A Stark, Agata A Ulanicka, Jennifer E Easterbrook, Malcolm G Dunlop, Jack Satsangi
Published 2011-01-01

Correction: changes to serum sample tube and processing methodology does not cause inter-individual variation in automated whole serum N-glycan profiling in health and disease.

by Nicholas T Ventham, Richard A Gardner, Nicholas A Kennedy, Archana Shubhakar, Rahul Kalla, Elaine R Nimmo, IBD-BIOM Consortium, Daryl L Fernandes, Jack Satsangi, Daniel I R Spencer
Published 2015-01-01

Changes to serum sample tube and processing methodology does not cause Intra-Individual [corrected] variation in automated whole serum N-glycan profiling in health and disease.

by Nicholas T Ventham, Richard A Gardner, Nicholas A Kennedy, Archana Shubhakar, Rahul Kalla, Elaine R Nimmo, IBD-BIOM Consortium, Daryl L Fernandes, Jack Satsangi, Daniel I R Spencer
Published 2015-01-01

The impact of different DNA extraction kits and laboratories upon the assessment of human gut microbiota composition by 16S rRNA gene sequencing.

by Nicholas A Kennedy, Alan W Walker, Susan H Berry, Sylvia H Duncan, Freda M Farquarson, Petra Louis, John M Thomson, UK IBD Genetics Consortium, Jack Satsangi, Harry J Flint, Julian Parkhill, Charlie W Lees, Georgina L Hold
Published 2014-01-01

Promoter methylation of the MGAT3 and BACH2 genes correlates with the composition of the immunoglobulin G glycome in inflammatory bowel disease

by Marija Klasić, Dora Markulin, Aleksandar Vojta, Ivana Samaržija, Ivan Biruš, Paula Dobrinić, Nicholas T. Ventham, Irena Trbojević-Akmačić, Mirna Šimurina, Jerko Štambuk, Genadij Razdorov, Nicholas A. Kennedy, Jack Satsangi, Ana M. Dias, Salome Pinho, Vito Annese, Anna Latiano, Renata D’Inca, IBD consortium, Gordan Lauc, Vlatka Zoldoš
Published 2018-06-01

Genetic variation in the familial Mediterranean fever gene (MEFV) and risk for Crohn's disease and ulcerative colitis.

by Alexandra-Chloé Villani, Mathieu Lemire, Edouard Louis, Mark S Silverberg, Catherine Collette, Geneviève Fortin, Elaine R Nimmo, Yannick Renaud, Sébastien Brunet, Cécile Libioulle, Jacques Belaiche, Alain Bitton, Daniel Gaudet, Albert Cohen, Diane Langelier, John D Rioux, Ian D R Arnott, Gary E Wild, Paul Rutgeerts, Jack Satsangi, Séverine Vermeire, Thomas J Hudson, Denis Franchimont
Published 2009-09-01

Analysis of germline GLI1 variation implicates hedgehog signalling in the regulation of intestinal inflammatory pathways.

by Charlie W Lees, William J Zacharias, Mark Tremelling, Colin L Noble, Elaine R Nimmo, Albert Tenesa, Jennine Cornelius, Leif Torkvist, John Kao, Susan Farrington, Hazel E Drummond, Gwo-Tzer Ho, Ian D R Arnott, Henry D Appelman, Lauri Diehl, Harry Campbell, Malcolm G Dunlop, Miles Parkes, Sarah E M Howie, Deborah L Gumucio, Jack Satsangi
Published 2008-12-01

Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroentero...

by Mark S Silverberg, Jack Satsangi, Tariq Ahmad, Ian DR Arnott, Charles N Bernstein, Steven R Brant, Renzo Caprilli, Jean-Frédéric Colombel, Christoph Gasche, Karel Geboes, Derek P Jewell, Amir Karban, Edward V Loftus, A Salvador Peña, Robert H Riddell, David B Sachar, Stefan Schreiber, A Hillary Steinhart, Stephan R Targan, Severine Vermeire, Bryan F Warren
Published 2005-01-01

Autologous stem cell transplantation in refractory Crohn’s disease – low intensity therapy evaluation (ASTIClite): study protocols for a multicentre, randomised controlled trial an...

by John A. Snowden, Chris Hawkey, Daniel Hind, Lizzie Swaby, Katie Mellor, Richard Emsley, Laura Mandefield, Ellen Lee, Manuela Badoglio, Emmanuelle Polge, Myriam Labopin, John Gribben, A. Graham Pockley, Gemma A. Foulds, Alan Lobo, Simon Travis, Miles Parkes, Jack Satsangi, Diana Papaioannou, James O. Lindsay, on Behalf of the Autologous Stem Cell Transplantation In Refractory CD - Low Intensity Therapy Evaluation Study Investigators, the European Society for Blood and Marrow Transplantation (EBMT) Autoimmune Diseases Working Party (ADWP)
Published 2019-05-01

Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes.

by Natalie J Prescott, Benjamin Lehne, Kristina Stone, James C Lee, Kirstin Taylor, Jo Knight, Efterpi Papouli, Muddassar M Mirza, Michael A Simpson, Sarah L Spain, Grace Lu, Franca Fraternali, Suzannah J Bumpstead, Emma Gray, Ariella Amar, Hannah Bye, Peter Green, Guy Chung-Faye, Bu'Hussain Hayee, Richard Pollok, Jack Satsangi, Miles Parkes, Jeffrey C Barrett, John C Mansfield, Jeremy Sanderson, Cathryn M Lewis, Michael E Weale, Thomas Schlitt, Christopher G Mathew, UK IBD Genetics Consortium
Published 2015-02-01

Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease.

by J Kenneth Baillie, Andrew Bretherick, Christopher S Haley, Sara Clohisey, Alan Gray, Lucile P A Neyton, Jeffrey Barrett, Eli A Stahl, Albert Tenesa, Robin Andersson, J Ben Brown, Geoffrey J Faulkner, Marina Lizio, Ulf Schaefer, Carsten Daub, Masayoshi Itoh, Naoto Kondo, Timo Lassmann, Jun Kawai, IIBDGC Consortium, Damian Mole, Vladimir B Bajic, Peter Heutink, Michael Rehli, Hideya Kawaji, Albin Sandelin, Harukazu Suzuki, Jack Satsangi, Christine A Wells, Nir Hacohen, Thomas C Freeman, Yoshihide Hayashizaki, Piero Carninci, Alistair R R Forrest, David A Hume
Published 2018-03-01

Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease

by Eva Gonçalves Serra, Tobias Schwerd, Loukas Moutsianas, Athena Cavounidis, Laura Fachal, Sumeet Pandey, Jochen Kammermeier, Nicholas M. Croft, Carsten Posovszky, Astor Rodrigues, Richard K. Russell, Farah Barakat, Marcus K. H. Auth, Robert Heuschkel, Matthias Zilbauer, Krzysztof Fyderek, Christian Braegger, Simon P. Travis, Jack Satsangi, Miles Parkes, Nikhil Thapar, Helen Ferry, Julie C. Matte, Kimberly C. Gilmour, Andrzej Wedrychowicz, Peter Sullivan, Carmel Moore, Jennifer Sambrook, Willem Ouwehand, David Roberts, John Danesh, Toni A. Baeumler, Tudor A. Fulga, Mohammad Karaminejadranjbar, Ahmed Ahmed, Rachel Wilson, Jeffrey C. Barrett, Abdul Elkadri, Anne M. Griffiths, COLORS in IBD group investigators, Oxford IBD cohort study investigators, INTERVAL Study, Swiss IBD cohort investigators, UK IBD Genetics Consortium, NIDDK IBD Genetics Consortium, Scott B. Snapper, Neil Shah, Aleixo M. Muise, David C. Wilson, Holm H. Uhlig, Carl A. Anderson
Published 2020-02-01