Impact of sarcoplasmic reticulum calcium release on calcium dynamics and action potential morphology in human atrial myocytes: a computational study.

by Jussi T Koivumäki, Topi Korhonen, Pasi Tavi
Published 2011-01-01

In silico screening of the key cellular remodeling targets in chronic atrial fibrillation.

by Jussi T Koivumäki, Gunnar Seemann, Mary M Maleckar, Pasi Tavi
Published 2014-05-01

Benchmarking electrophysiological models of human atrial myocytes

by Mathias eWilhelms, Hanne eHettmann, Mary Margot Catherine Maleckar, Mary Margot Catherine Maleckar, Jussi T Koivumäki, Jussi T Koivumäki, Olaf eDössel, Gunnar eSeemann
Published 2013-01-01

Comparison of the Simulated Response of Three in Silico Human Stem Cell-Derived Cardiomyocytes Models and in Vitro Data Under 15 Drug Actions

by Michelangelo Paci, Jussi T. Koivumäki, Hua Rong Lu, David J. Gallacher, Elisa Passini, Blanca Rodriguez
Published 2021-03-01

Computational Modeling of Electrophysiology and Pharmacotherapy of Atrial Fibrillation: Recent Advances and Future Challenges

by Márcia Vagos, Márcia Vagos, Ilsbeth G. M. van Herck, Ilsbeth G. M. van Herck, Joakim Sundnes, Joakim Sundnes, Hermenegild J. Arevalo, Hermenegild J. Arevalo, Andrew G. Edwards, Andrew G. Edwards, Jussi T. Koivumäki, Jussi T. Koivumäki
Published 2018-09-01

hiPSC-Derived Cardiomyocyte Model of LQT2 Syndrome Derived from Asymptomatic and Symptomatic Mutation Carriers Reproduces Clinical Differences in Aggregates but Not in Single Cells

by Disheet Shah, Chandra Prajapati, Kirsi Penttinen, Reeja Maria Cherian, Jussi T. Koivumäki, Anna Alexanova, Jari Hyttinen, Katriina Aalto-Setälä
Published 2020-05-01

Na+ current expression in human atrial myofibroblasts:identity and functional roles

by Jussi Tapani Koivumäki, Robert eClark, Darrell eBelke, Colleen eKondo, Paul W. M. Fedak, Mary Margot Catherine Maleckar, Wayne Rodney Giles
Published 2014-08-01

Vascular Endothelial Growth Factor-B Induces a Distinct Electrophysiological Phenotype in Mouse Heart

by Nikolay Naumenko, Jenni Huusko, Tomi Tuomainen, Jussi T. Koivumäki, Mari Merentie, Erika Gurzeler, Kari Alitalo, Riikka Kivelä, Seppo Ylä-Herttuala, Seppo Ylä-Herttuala, Pasi Tavi
Published 2017-05-01

Structural Immaturity of Human iPSC-Derived Cardiomyocytes: In Silico Investigation of Effects on Function and Disease Modeling

by Jussi T. Koivumäki, Nikolay Naumenko, Tomi Tuomainen, Jouni Takalo, Jouni Takalo, Minna Oksanen, Katja A. Puttonen, Šárka Lehtonen, Johanna Kuusisto, Markku Laakso, Jari Koistinaho, Pasi Tavi
Published 2018-02-01

Cardiomyocytes: Analysis of Temperature Response and Signal Propagation Between Dissociated Clusters Using Novel Video-Based Movement Analysis Software

by Dhanesh Kattipparambil Rajan, Antti-Juhana Maki, Mari Pekkanen-Mattila, Joose Kreutzer, Tomi Ryynanen, Hannu Valimaki, Jarmo Verho, Jussi T. Koivumaki, Heimo Ihalainen, Katriina Aalto-Setala, Pasi Kallio, Jukka Lekkala
Published 2020-01-01

Case Report on: Very Early Afterdepolarizations in HiPSC-Cardiomyocytes—An Artifact by Big Conductance Calcium Activated Potassium Current (I_bk,Ca)

by András Horváth, Torsten Christ, Jussi T. Koivumäki, Maksymilian Prondzynski, Antonia T. L. Zech, Michael Spohn, Umber Saleem, Ingra Mannhardt, Bärbel Ulmer, Evaldas Girdauskas, Christian Meyer, Arne Hansen, Thomas Eschenhagen, Marc D. Lemoine
Published 2020-01-01

Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy

by Maksymilian Prondzynski, Marc D Lemoine, Antonia TL Zech, András Horváth, Vittoria Di Mauro, Jussi T Koivumäki, Nico Kresin, Josefine Busch, Tobias Krause, Elisabeth Krämer, Saskia Schlossarek, Michael Spohn, Felix W Friedrich, Julia Münch, Sandra D Laufer, Charles Redwood, Alexander E Volk, Arne Hansen, Giulia Mearini, Daniele Catalucci, Christian Meyer, Torsten Christ, Monica Patten, Thomas Eschenhagen, Lucie Carrier
Published 2019-12-01