Nebivolol Desensitizes Myofilaments of a Hypertrophic Cardiomyopathy Mouse Model

by Sabrina Stücker, Sabrina Stücker, Nico Kresin, Nico Kresin, Lucie Carrier, Lucie Carrier, Felix W. Friedrich, Felix W. Friedrich
Published 2017-08-01

Epigallocatechin-3-gallate accelerates relaxation and Ca2+ transient decay and desensitizes myofilaments in healthy and Mybpc3-targeted knock-in cardiomyopathic mice

by Felix W. Friedrich, Felix W. Friedrich, Frederik Flenner, Frederik Flenner, Mahtab Nasib, Mahtab Nasib, Thomas Eschenhagen, Thomas Eschenhagen, Lucie Carrier, Lucie Carrier
Published 2016-12-01

Is Desmin Propensity to Aggregate Part of its Protective Function?

by Sonia R. Singh, Hikmet Kadioglu, Krishna Patel, Lucie Carrier, Giulio Agnetti
Published 2020-02-01

A Transgenic Mouse Model of Eccentric Left Ventricular Hypertrophy With Preserved Ejection Fraction Exhibits Alterations in the Autophagy-Lysosomal Pathway

by Kristin Wenzel, Kristin Wenzel, Elisabeth Krämer, Elisabeth Krämer, Birgit Geertz, Birgit Geertz, Lucie Carrier, Lucie Carrier, Stephan B. Felix, Stephan B. Felix, Stephanie Könemann, Stephanie Könemann, Saskia Schlossarek, Saskia Schlossarek
Published 2021-04-01

Analysis of Contractile Function of Permeabilized Human Hypertrophic Cardiomyopathy Multicellular Heart Tissue

by Nico Kresin, Nico Kresin, Sabrina Stücker, Sabrina Stücker, Elisabeth Krämer, Elisabeth Krämer, Frederik Flenner, Frederik Flenner, Giulia Mearini, Giulia Mearini, Julia Münch, Monica Patten, Charles Redwood, Lucie Carrier, Lucie Carrier, Felix W. Friedrich, Felix W. Friedrich
Published 2019-03-01

Cardiovascular magnetic resonance detects microvascular dysfunction in a mouse model of hypertrophic cardiomyopathy

by Min-Chi Ku, Frank Kober, Yi-Ching Lai, Andreas Pohlmann, Fatimunnisa Qadri, Michael Bader, Lucie Carrier, Thoralf Niendorf
Published 2021-05-01

Association of Asymmetric Dimethylarginine and Diastolic Dysfunction in Patients with Hypertrophic Cardiomyopathy

by Kathrin Cordts, Doreen Seelig, Natalie Lund, Lucie Carrier, Rainer H. Böger, Maxim Avanesov, Enver Tahir, Edzard Schwedhelm, Monica Patten
Published 2019-07-01

I-1-deficiency negatively impacts survival in a cardiomyopathy mouse model

by Felix W. Friedrich, Hannieh Sotoud, Birgit Geertz, Silvio Weber, Frederik Flenner, Silke Reischmann, Thomas Eschenhagen, Lucie Carrier, Ali El-Armouche
Published 2015-09-01

S100A4 as a Target of the E3-Ligase Asb2β and Its Effect on Engineered Heart Tissue

by Simon Braumann, Simon Braumann, Simon Braumann, Tilo Thottakara, Tilo Thottakara, Sabrina Stücker, Sabrina Stücker, Silke Reischmann-Düsener, Silke Reischmann-Düsener, Elisabeth Krämer, Elisabeth Krämer, Julia Groß, Julia Groß, Marc N. Hirt, Marc N. Hirt, Shirin Doroudgar, Shirin Doroudgar, Lucie Carrier, Lucie Carrier, Felix W. Friedrich, Felix W. Friedrich
Published 2018-09-01

BSE-associated Prion-Amyloid Cardiomyopathy in Primates

by Susanne Krasemann, Giulia Mearini, Elisabeth Krämer, Katja Wagenführ, Walter Schulz-Schaeffer, Melanie Neumann, Walter Bodemer, Franz-Josef Kaup, Michael Beekes, Lucie Carrier, Adriano Aguzzi, Markus Glatzel
Published 2013-06-01

Aldosterone inhibits the fetal program and increases hypertrophy in the heart of hypertensive mice.

by Feriel Azibani, Yvan Devaux, Guillaume Coutance, Saskia Schlossarek, Evelyne Polidano, Loubina Fazal, Regine Merval, Lucie Carrier, Alain Cohen Solal, Christos Chatziantoniou, Jean-Marie Launay, Jane-Lise Samuel, Claude Delcayre
Published 2012-01-01

Distinctive serum miRNA profile in mouse models of striated muscular pathologies.

by Nicolas Vignier, Fatima Amor, Paul Fogel, Angélique Duvallet, Jérôme Poupiot, Sabine Charrier, Michel Arock, Marie Montus, Isabelle Nelson, Isabelle Richard, Lucie Carrier, Laurent Servais, Thomas Voit, Gisèle Bonne, David Israeli
Published 2013-01-01

Evaluation of MYBPC3 trans-Splicing and Gene Replacement as Therapeutic Options in Human iPSC-Derived Cardiomyocytes

by Maksymilian Prondzynski, Elisabeth Krämer, Sandra D. Laufer, Aya Shibamiya, Ole Pless, Frederik Flenner, Oliver J. Müller, Julia Münch, Charles Redwood, Arne Hansen, Monica Patten, Thomas Eschenhagen, Giulia Mearini, Lucie Carrier
Published 2017-06-01

Repair of Mybpc3 mRNA by 5′-trans-splicing in a Mouse Model of Hypertrophic Cardiomyopathy

by Giulia Mearini, Doreen Stimpel, Elisabeth Krämer, Birgit Geertz, Ingke Braren, Christina Gedicke-Hornung, Guillaume Précigout, Oliver J Müller, Hugo A Katus, Thomas Eschenhagen, Thomas Voit, Luis Garcia, Stéphanie Lorain, Lucie Carrier
Published 2013-01-01

Generation of bi-allelic MYBPC3 truncating mutant and isogenic control from an iPSC line of a patient with hypertrophic cardiomyopathy

by Nele Warnecke, Bärbel M. Ulmer, Sandra D. Laufer, Aya Shibamiya, Elisabeth Krämer, Christiane Neuber, Sophia Hanke, Charlotta Behrens, Malte Loos, Julia Münch, Jirko Kühnisch, Sabine Klaassen, Thomas Eschenhagen, Monica Patten-Hamel, Lucie Carrier, Giulia Mearini
Published 2021-08-01

Targeted Mybpc3 Knock-Out Mice with Cardiac Hypertrophy Exhibit Structural Mitral Valve Abnormalities

by Daniel P. Judge, Hany Neamatalla, Russell A. Norris, Robert A. Levine, Jonathan T. Butcher, Nicolas Vignier, Kevin H. Kang, Quangtung Nguyen, Patrick Bruneval, Marie-Cécile Perier, Emmanuel Messas, Xavier Jeunemaitre, Annemarieke de Vlaming, Roger Markwald, Lucie Carrier, Albert A. Hagège
Published 2015-04-01

Impact of AT2 receptor deficiency on postnatal cardiovascular development.

by Daniel Biermann, Andreas Heilmann, Michael Didié, Saskia Schlossarek, Azadeh Wahab, Michael Grimm, Maria Römer, Hermann Reichenspurner, Karim R Sultan, Anna Steenpass, Süleyman Ergün, Sonia Donzelli, Lucie Carrier, Heimo Ehmke, Wolfram H Zimmermann, Lutz Hein, Rainer H Böger, Ralf A Benndorf
Published 2012-01-01

Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy

by Maksymilian Prondzynski, Marc D Lemoine, Antonia TL Zech, András Horváth, Vittoria Di Mauro, Jussi T Koivumäki, Nico Kresin, Josefine Busch, Tobias Krause, Elisabeth Krämer, Saskia Schlossarek, Michael Spohn, Felix W Friedrich, Julia Münch, Sandra D Laufer, Charles Redwood, Alexander E Volk, Arne Hansen, Giulia Mearini, Daniele Catalucci, Christian Meyer, Torsten Christ, Monica Patten, Thomas Eschenhagen, Lucie Carrier
Published 2019-12-01