MicroRNA-155—at the Critical Interface of Innate and Adaptive Immunity in Arthritis

by Stefano Alivernini, Elisa Gremese, Charles McSharry, Barbara Tolusso, Gianfranco Ferraccioli, Iain B. McInnes, Iain B. McInnes, Mariola Kurowska-Stolarska, Mariola Kurowska-Stolarska
Published 2018-01-01

Nanoparticles and Inflammation

by Ross Stevenson, Axel J. Hueber, Alan Hutton, Iain B. McInnes, Duncan Graham
Published 2011-01-01

Th17 effector cells support B cell responses outside of germinal centres.

by Agapitos Patakas, Robert A Benson, David R Withers, Paola Conigliaro, Iain B McInnes, James M Brewer, Paul Garside
Published 2012-01-01

Identification of urinary peptide biomarkers associated with rheumatoid arthritis.

by Angelique Stalmach, Hanna Johnsson, Iain B McInnes, Holger Husi, Julie Klein, Mohammed Dakna, William Mullen, Harald Mischak, Duncan Porter
Published 2014-01-01

Sphingosine-1-Phosphate Promotes the Persistence of Activated CD4 T Cells in Inflamed Sites

by Shafqat Ahrar Jaigirdar, Robert A. Benson, Aziza Elmesmari, Mariola Stefania Kurowska-Stolarska, Iain B. McInnes, Paul Garside, Megan K. L. MacLeod
Published 2017-11-01

Chromosome conformation signatures define predictive markers of inadequate response to methotrexate in early rheumatoid arthritis

by Claudio Carini, Ewan Hunter, Scottish Early Rheumatoid Arthritis Inception cohort Investigators, Aroul S. Ramadass, Jayne Green, Alexandre Akoulitchev, Iain B. McInnes, Carl S. Goodyear
Published 2018-01-01

MiR-155 has a protective role in the development of non-alcoholic hepatosteatosis in mice.

by Ashley M Miller, Derek S Gilchrist, Jagtar Nijjar, Elisa Araldi, Cristina M Ramirez, Christopher A Lavery, Carlos Fernández-Hernando, Iain B McInnes, Mariola Kurowska-Stolarska
Published 2013-01-01

Changes in Plasma Itaconate Elevation in Early Rheumatoid Arthritis Patients Elucidates Disease Activity Associated Macrophage Activation

by Rónán Daly, Gavin Blackburn, Cameron Best, Carl S. Goodyear, Manikhandan Mudaliar, Karl Burgess, Anne Stirling, Duncan Porter, Iain B. McInnes, Michael P. Barrett, James Dale
Published 2020-06-01

In Human Autoimmunity, a Substantial Component of the B Cell Repertoire Consists of Polyclonal, Barely Mutated IgG+ve B Cells

by Graeme J. M. Cowan, Katherine Miles, Lorenzo Capitani, Sophie S. B. Giguere, Sophie S. B. Giguere, Hanna Johnsson, Carl Goodyear, Iain B. McInnes, Steffen Breusch, David Gray, Mohini Gray
Published 2020-03-01

Fibroblast activation and inflammation in frozen shoulder.

by Moeed Akbar, Michael McLean, Emma Garcia-Melchor, Lindsay An Crowe, Paul McMillan, Umberto G Fazzi, David Martin, Angus Arthur, James H Reilly, Iain B McInnes, Neal L Millar
Published 2019-01-01

Secukinumab provides rapid and sustained pain relief in psoriatic arthritis over 2 years: results from the FUTURE 2 study

by Iain B. McInnes, Philip J. Mease, Georg Schett, Bruce Kirkham, Vibeke Strand, Nicole Williams, Todd Fox, Luminita Pricop, Steffen M. Jugl, Kunal K. Gandhi, on behalf of the FUTURE 2 Study Group
Published 2018-06-01

Efficacy and safety of secukinumab administration by autoinjector in patients with psoriatic arthritis: results from a randomized, placebo-controlled trial (FUTURE 3)

by Peter Nash, Philip J. Mease, Iain B. McInnes, Proton Rahman, Christopher T. Ritchlin, Ricardo Blanco, Eva Dokoupilova, Mats Andersson, Radhika Kajekar, Shephard Mpofu, Luminita Pricop, on behalf of the FUTURE 3 study group
Published 2018-03-01

Full Length Interleukin 33 Aggravates Radiation-Induced Skin Reaction

by Olga Kurow, Benjamin Frey, Louis Schuster, Verena Schmitt, Susanne Adam, Madelaine Hahn, Derek Gilchrist, Iain B. McInnes, Stefan Wirtz, Udo S. Gaipl, Gerhard Krönke, Georg Schett, Silke Frey, Axel J. Hueber
Published 2017-06-01

MicroRNA-155 influences B-cell function through PU.1 in rheumatoid arthritis

by Stefano Alivernini, Mariola Kurowska-Stolarska, Barbara Tolusso, Roberta Benvenuto, Aziza Elmesmari, Silvia Canestri, Luca Petricca, Antonella Mangoni, Anna Laura Fedele, Clara Di Mario, Maria Rita Gigante, Elisa Gremese, Iain B. McInnes, Gianfranco Ferraccioli
Published 2016-09-01

Secukinumab efficacy on resolution of enthesitis in psoriatic arthritis: pooled analysis of two phase 3 studies

by Laura C. Coates, Johan K. Wallman, Dennis McGonagle, Georg A. Schett, Iain B. McInnes, Philip J. Mease, Lawrence Rasouliyan, Erhard Quebe-Fehling, Darren L. Asquith, Andreas E. R. Fasth, Luminita Pricop, Corine Gaillez
Published 2019-12-01

Comparison of baricitinib, upadacitinib, and tofacitinib mediated regulation of cytokine signaling in human leukocyte subpopulations

by Iain B. McInnes, Nicole L. Byers, Richard E. Higgs, Jonathan Lee, William L. Macias, Songqing Na, Robert A. Ortmann, Guilherme Rocha, Terence P. Rooney, Thomas Wehrman, Xin Zhang, Steven H. Zuckerman, Peter C. Taylor
Published 2019-08-01

Soluble ST2 associates with diabetes but not established cardiovascular risk factors: a new inflammatory pathway of relevance to diabetes?

by Ashley M Miller, David Purves, Alex McConnachie, Darren L Asquith, G David Batty, Harry Burns, Jonathan Cavanagh, Ian Ford, Jennifer S McLean, Chris J Packard, Paul G Shiels, Helen Turner, Yoga N Velupillai, Kevin A Deans, Paul Welsh, Iain B McInnes, Naveed Sattar
Published 2012-01-01

MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis

by Mariola Kurowska-Stolarska, Stefano Alivernini, Emma Garcia Melchor, Aziza Elmesmari, Barbara Tolusso, Clare Tange, Luca Petricca, Derek S. Gilchrist, Gabriele Di Sante, Chantal Keijzer, Lynn Stewart, Clara Di Mario, Vicky Morrison, James M. Brewer, Duncan Porter, Simon Milling, Ronald D. Baxter, David McCarey, Elisa Gremese, Greg Lemke, Gianfranco Ferraccioli, Charles McSharry, Iain B. McInnes
Published 2017-06-01

Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study.

by Ashley Budu-Aggrey, Ben Brumpton, Jess Tyrrell, Sarah Watkins, Ellen H Modalsli, Carlos Celis-Morales, Lyn D Ferguson, Gunnhild Åberge Vie, Tom Palmer, Lars G Fritsche, Mari Løset, Jonas Bille Nielsen, Wei Zhou, Lam C Tsoi, Andrew R Wood, Samuel E Jones, Robin Beaumont, Marit Saunes, Pål Richard Romundstad, Stefan Siebert, Iain B McInnes, James T Elder, George Davey Smith, Timothy M Frayling, Bjørn Olav Åsvold, Sara J Brown, Naveed Sattar, Lavinia Paternoster
Published 2019-01-01

Arthritis prevention in the pre-clinical phase of RA with abatacept (the APIPPRA study): a multi-centre, randomised, double-blind, parallel-group, placebo-controlled clinical trial...

by Mariam Al-Laith, Marianna Jasenecova, Sonya Abraham, Aisla Bosworth, Ian N. Bruce, Christopher D. Buckley, Coziana Ciurtin, Maria-Antonietta D’Agostino, Paul Emery, Hill Gaston, John D. Isaacs, Andrew Filer, Benjamin A. Fisher, Thomas W. J. Huizinga, Pauline Ho, Clare Jacklin, Heidi Lempp, Iain B. McInnes, Arthur G. Pratt, Andrew Östor, Karim Raza, Peter C. Taylor, Dirkjan van Schaardenburg, Dharshene Shivapatham, Alison J. Wright, Joana C. Vasconcelos, Joanna Kelly, Caroline Murphy, A. Toby Prevost, Andrew P. Cope
Published 2019-07-01