Harmful waste products as novel immune modulators for treating inflammatory arthritis?

by Andrew P Cope
Published 2006-09-01

A systematic review of CXCL13 as a biomarker of disease and treatment response in rheumatoid arthritis

by Katie Bechman, Anthony Dalrymple, Charles Southey-Bassols, Andrew P. Cope, James B. Galloway
Published 2020-11-01

PTPN22 Acts in a Cell Intrinsic Manner to Restrict the Proliferation and Differentiation of T Cells Following Antibody Lymphodepletion

by Johanna A. Knipper, David Wright, Andrew P. Cope, Bernard Malissen, Bernard Malissen, Rose Zamoyska
Published 2020-01-01

Inhibitor of kappa B epsilon (IκBε) is a non-redundant regulator of c-Rel-dependent gene expression in murine T and B cells.

by Joanna M Clark, Karolina Aleksiyadis, Alex Martin, Kay McNamee, Tharsana Tharmalingam, Richard O Williams, Sylvie Mémet, Andrew P Cope
Published 2011-01-01

Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production.

by Matthew J Peirce, Matthew Brook, Nicholas Morrice, Robert Snelgrove, Shajna Begum, Alessandra Lanfrancotti, Clare Notley, Tracy Hussell, Andrew P Cope, Robin Wait
Published 2010-07-01

Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation.

by Vicky Nicolaidou, Mei Mei Wong, Andia N Redpath, Adel Ersek, Dilair F Baban, Lynn M Williams, Andrew P Cope, Nicole J Horwood
Published 2012-01-01

Real world long-term impact of intensive treatment on disease activity, disability and health-related quality of life in rheumatoid arthritis

by Nicola J. Gullick, Fowzia Ibrahim, Ian C. Scott, Alexandra Vincent, Andrew P. Cope, Toby Garrood, Gabriel S. Panayi, David L. Scott, Bruce W. Kirkham, On behalf of TITRATE Programme Investigators
Published 2019-02-01

Cholesterol metabolism drives regulatory B cell IL-10 through provision of geranylgeranyl pyrophosphate

by Jack A. Bibby, Harriet A. Purvis, Thomas Hayday, Anita Chandra, Klaus Okkenhaug, Sofia Rosenzweig, Ivona Aksentijevich, Michael Wood, Helen J. Lachmann, Claudia Kemper, Andrew P. Cope, Esperanza Perucha
Published 2020-07-01

Protein tyrosine phosphatase PTPN22 is dispensable for dendritic cell antigen processing and promotion of T-cell activation by dendritic cells.

by Fiona Clarke, Christine K Jordan, Enrique Gutiérrez-Martinez, Jack A Bibby, Cristina Sanchez-Blanco, Georgina H Cornish, Xuezhi Dai, David J Rawlings, Rose Zamoyska, Pierre Guermonprez, Andrew P Cope, Harriet A Purvis
Published 2017-01-01

3D Bayesian cluster analysis of super-resolution data reveals LAT recruitment to the T cell synapse

by Juliette Griffié, Leigh Shlomovich, David J. Williamson, Michael Shannon, Jesse Aaron, Satya Khuon, Garth L. Burn, Lies Boelen, Ruby Peters, Andrew P. Cope, Edward A. K. Cohen, Patrick Rubin-Delanchy, Dylan M. Owen
Published 2017-06-01

Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking.

by Ian C Scott, Seth D Seegobin, Sophia Steer, Rachael Tan, Paola Forabosco, Anne Hinks, Stephen Eyre, Ann W Morgan, Anthony G Wilson, Lynne J Hocking, Paul Wordsworth, Anne Barton, Jane Worthington, Andrew P Cope, Cathryn M Lewis
Published 2013-01-01

Correction: Predicting the Risk of Rheumatoid Arthritis and Its Age of Onset through Modelling Genetic Risk Variants with Smoking

by Ian C. Scott, Seth D. Seegobin, Sophia Steer, Rachael Tan, Paola Forabosco, Anne Hinks, Stephen Eyre, Ann W. Morgan, Anthony G. Wilson, Lynne J. Hocking, Paul Wordsworth, Anne Barton, Jane Worthington, Andrew P. Cope, Cathryn M. Lewis
Published 2013-10-01

Correction: Predicting the Risk of Rheumatoid Arthritis and Its Age of Onset through Modelling Genetic Risk Variants with Smoking.

by Ian C. Scott, Seth D. Seegobin, Sophia Steer, Rachael Tan, Paola Forabosco, Anne Hinks, Stephen Eyre, Ann W. Morgan, Anthony G. Wilson, Lynne J. Hocking, Paul Wordsworth, Anne Barton, Jane Worthington, Andrew P. Cope, Cathryn M. Lewis
Published 2013-10-01

Phosphatase PTPN22 Regulates Dendritic Cell Homeostasis and cDC2 Dependent T Cell Responses

by Harriet A. Purvis, Fiona Clarke, Anna B. Montgomery, Chloe Colas, Jack A. Bibby, Georgina H. Cornish, Xuezhi Dai, Xuezhi Dai, Xuezhi Dai, Diana Dudziak, David J. Rawlings, David J. Rawlings, David J. Rawlings, Rose Zamoyska, Pierre Guermonprez, Pierre Guermonprez, Andrew P. Cope
Published 2020-03-01

Correction to: The citrullinated/native index of autoantibodies against hnRNP-DL predicts an individual “window of treatment success” in RA patients

by Bianka Marklein, Madeleine Jenning, Zoltán Konthur, Thomas Häupl, Franziska Welzel, Ute Nonhoff, Sylvia Krobitsch, Debbie M. Mulder, Marije I. Koenders, Vijay Joshua, Andrew P. Cope, Mark J. Shlomchik, Hans-Joachim Anders, Gerd R. Burmester, Aase Hensvold, Anca I. Catrina, Johan Rönnelid, Günter Steiner, Karl Skriner
Published 2021-10-01

The citrullinated/native index of autoantibodies against hnRNP-DL predicts an individual “window of treatment success” in RA patients

by Bianka Marklein, Madeleine Jenning, Zoltán Konthur, Thomas Häupl, Franziska Welzel, Ute Nonhoff, Sylvia Krobitsch, Debbie M. Mulder, Marije I. Koenders, Vijay Joshua, Andrew P. Cope, Mark J. Shlomchik, Hans-Joachim Anders, Gerd R. Burmester, Aase Hensvold, Anca I. Catrina, Johan Rönnelid, Günter Steiner, Karl Skriner
Published 2021-09-01

The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells

by Esperanza Perucha, Rossella Melchiotti, Jack A Bibby, Wing Wu, Klaus Stensgaard Frederiksen, Ceri A. Roberts, Zoe Hall, Gaelle LeFriec, Kevin A. Robertson, Paul Lavender, Jens Gammeltoft Gerwien, Leonie S. Taams, Julian L. Griffin, Emanuele de Rinaldis, Lisa G. M. van Baarsen, Claudia Kemper, Peter Ghazal, Andrew P. Cope
Published 2019-01-01

Genetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases.

by Matthew Traylor, Rachel Knevel, Jing Cui, John Taylor, Westra Harm-Jan, Philip G Conaghan, Andrew P Cope, Charles Curtis, Paul Emery, Stephen Newhouse, Hamel Patel, Sophia Steer, Peter Gregersen, Nancy A Shadick, Michael E Weinblatt, Annette Van Der Helm-van Mil, Jennifer H Barrett, Ann W Morgan, Cathryn M Lewis, Ian C Scott
Published 2019-01-01

Arthritis prevention in the pre-clinical phase of RA with abatacept (the APIPPRA study): a multi-centre, randomised, double-blind, parallel-group, placebo-controlled clinical trial...

by Mariam Al-Laith, Marianna Jasenecova, Sonya Abraham, Aisla Bosworth, Ian N. Bruce, Christopher D. Buckley, Coziana Ciurtin, Maria-Antonietta D’Agostino, Paul Emery, Hill Gaston, John D. Isaacs, Andrew Filer, Benjamin A. Fisher, Thomas W. J. Huizinga, Pauline Ho, Clare Jacklin, Heidi Lempp, Iain B. McInnes, Arthur G. Pratt, Andrew Östor, Karim Raza, Peter C. Taylor, Dirkjan van Schaardenburg, Dharshene Shivapatham, Alison J. Wright, Joana C. Vasconcelos, Joanna Kelly, Caroline Murphy, A. Toby Prevost, Andrew P. Cope
Published 2019-07-01