Aging is not associated with proteasome impairment in UPS reporter mice.

by Casey Cook, Jennifer Gass, Judith Dunmore, Jimei Tong, Julie Taylor, Jason Eriksen, Eileen McGowan, Jada Lewis, Jennifer Johnston, Leonard Petrucelli
Published 2009-06-01

The pathological phenotypes of human TDP-43 transgenic mouse models are independent of downregulation of mouse Tdp-43.

by Ya-Fei Xu, Mercedes Prudencio, Jaime M Hubbard, Jimei Tong, Ena C Whitelaw, Karen Jansen-West, Caroline Stetler, Xiangkun Cao, John Song, Yong-Jie Zhang
Published 2013-01-01

Microglial lysosome dysfunction contributes to white matter pathology and TDP-43 proteinopathy in GRN-associated FTD

by Yanwei Wu, Wei Shao, Tiffany W. Todd, Jimei Tong, Mei Yue, Shunsuke Koga, Monica Castanedes-Casey, Ariston L. Librero, Chris W. Lee, Ian R. Mackenzie, Dennis W. Dickson, Yong-Jie Zhang, Leonard Petrucelli, Mercedes Prudencio
Published 2021-08-01

Enhanced phosphorylation of T153 in soluble tau is a defining biochemical feature of the A152T tau risk variant

by Yari Carlomagno, Dah-eun Chloe Chung, Mei Yue, Aishe Kurti, Nicole M. Avendano, Monica Castanedes-Casey, Kelly M. Hinkle, Karen Jansen-West, Lillian M. Daughrity, Jimei Tong, Virginia Phillips, Rosa Rademakers, Michael DeTure, John D. Fryer, Dennis W. Dickson, Leonard Petrucelli, Casey Cook
Published 2019-01-01

Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo

by Tiffany W. Todd, Zachary T. McEachin, Jeannie Chew, Alexander R. Burch, Karen Jansen-West, Jimei Tong, Mei Yue, Yuping Song, Monica Castanedes-Casey, Aishe Kurti, Judith H. Dunmore, John D. Fryer, Yong-Jie Zhang, Beatriz San Millan, Susana Teijeira Bautista, Manuel Arias, Dennis Dickson, Tania F. Gendron, María-Jesús Sobrido, Matthew D. Disney, Gary J. Bassell, Wilfried Rossoll, Leonard Petrucelli
Published 2020-05-01