Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations

by Meixiang Huang, Erica Modeste, Eric Dammer, Paola Merino, Georgia Taylor, Duc M. Duong, Qiudong Deng, Christopher J. Holler, Marla Gearing, Dennis Dickson, Nicholas T. Seyfried, Thomas Kukar
Published 2020-10-01

Lack of Nigral Pathology in Transgenic Mice Expressing Human α-Synuclein Driven by the Tyrosine Hydroxylase Promoter

by Yasuji Matsuoka, Miquel Vila, Sarah Lincoln, Alison McCormack, Melanie Picciano, John LaFrancois, Xin Yu, Dennis Dickson, William J. Langston, Eileen McGowan, Matt Farrer, John Hardy, Karen Duff, Serge Przedborski, Donato A. Di Monte
Published 2001-06-01

Modulating innate immune activation states impacts the efficacy of specific Aβ immunotherapy

by Yona Levites, Cory Funk, Xue Wang, Paramita Chakrabarty, Karen N. McFarland, Baxter Bramblett, Veronica O’Neal, Xufei Liu, Thomas Ladd, Max Robinson, Mariet Allen, Minerva M. Carrasquillo, Dennis Dickson, Pedro Cruz, Danny Ryu, Hong-Dong Li, Nathan D. Price, NIlüfer Ertekin-Taner, Todd E. Golde
Published 2021-05-01

Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo

by Tiffany W. Todd, Zachary T. McEachin, Jeannie Chew, Alexander R. Burch, Karen Jansen-West, Jimei Tong, Mei Yue, Yuping Song, Monica Castanedes-Casey, Aishe Kurti, Judith H. Dunmore, John D. Fryer, Yong-Jie Zhang, Beatriz San Millan, Susana Teijeira Bautista, Manuel Arias, Dennis Dickson, Tania F. Gendron, María-Jesús Sobrido, Matthew D. Disney, Gary J. Bassell, Wilfried Rossoll, Leonard Petrucelli
Published 2020-05-01

LRRTM3 interacts with APP and BACE1 and has variants associating with late-onset Alzheimer's disease (LOAD).

by Sarah Lincoln, Mariet Allen, Claire L Cox, Louise P Walker, Kimberly Malphrus, Yushi Qiu, Thuy Nguyen, Christopher Rowley, Naomi Kouri, Julia Crook, V Shane Pankratz, Samuel Younkin, Linda Younkin, Minerva Carrasquillo, Fanggeng Zou, Samer O Abdul-Hay, Wolfdieter Springer, Sigrid B Sando, Jan O Aasly, Maria Barcikowska, Zbigniew K Wszolek, Jada M Lewis, Dennis Dickson, Neill R Graff-Radford, Ronald C Petersen, Elizabeth Eckman, Steven G Younkin, Nilüfer Ertekin-Taner
Published 2013-01-01