TDP-1/TDP-43 regulates stress signaling and age-dependent proteotoxicity in Caenorhabditis elegans.

by Alexandra Vaccaro, Arnaud Tauffenberger, Peter E A Ash, Yari Carlomagno, Leonard Petrucelli, J Alex Parker
Published 2012-07-01

Casein kinase II induced polymerization of soluble TDP-43 into filaments is inhibited by heat shock proteins.

by Yari Carlomagno, Yongjie Zhang, Mary Davis, Wen-Lang Lin, Casey Cook, Judy Dunmore, William Tay, Kyle Menkosky, Xiangkun Cao, Leonard Petrucelli, Michael Deture
Published 2014-01-01

Tau exhibits unique seeding properties in globular glial tauopathy

by Dah-eun Chloe Chung, Yari Carlomagno, Casey N. Cook, Karen Jansen-West, Lillian Daughrity, Laura J. Lewis-Tuffin, Monica Castanedes-Casey, Michael DeTure, Dennis W. Dickson, Leonard Petrucelli
Published 2019-03-01

The lysosomal protein cathepsin L is a progranulin protease

by Chris W. Lee, Jeannette N. Stankowski, Jeannie Chew, Casey N. Cook, Ying-Wai Lam, Sandra Almeida, Yari Carlomagno, Kwok-Fai Lau, Mercedes Prudencio, Fen-Biao Gao, Matthew Bogyo, Dennis W. Dickson, Leonard Petrucelli
Published 2017-07-01

Enhanced phosphorylation of T153 in soluble tau is a defining biochemical feature of the A152T tau risk variant

by Yari Carlomagno, Dah-eun Chloe Chung, Mei Yue, Aishe Kurti, Nicole M. Avendano, Monica Castanedes-Casey, Kelly M. Hinkle, Karen Jansen-West, Lillian M. Daughrity, Jimei Tong, Virginia Phillips, Rosa Rademakers, Michael DeTure, John D. Fryer, Dennis W. Dickson, Leonard Petrucelli, Casey Cook
Published 2019-01-01

Clusterin ameliorates tau pathology in vivo by inhibiting fibril formation

by Aleksandra M. Wojtas, Yari Carlomagno, Jonathon P. Sens, Silvia S. Kang, Tanner D. Jensen, Aishe Kurti, Kelsey E. Baker, Taylor J. Berry, Virginia R. Phillips, Monica Casey Castanedes, Ayesha Awan, Michael DeTure, Cristhoper H. Fernandez De Castro, Ariston L. Librero, Mei Yue, Lillian Daughrity, Karen R. Jansen-West, Casey N. Cook, Dennis W. Dickson, Leonard Petrucelli, John D. Fryer
Published 2020-12-01