RNA-mediated toxicity in C9orf72 ALS and FTD

by Zachary T. McEachin, Janani Parameswaran, Nisha Raj, Gary J. Bassell, Jie Jiang
Published 2020-11-01

Divergent FUS phosphorylation in primate and mouse cells following double-strand DNA damage

by Michelle A. Johnson, Qiudong Deng, Georgia Taylor, Zachary T. McEachin, Anthony W.S. Chan, Jessica Root, Gary J. Bassell, Thomas Kukar
Published 2020-12-01

Assessing reproductive toxicity of two environmental toxicants with a novel in vitro human spermatogenic model

by Charles A. Easley, IV, Joshua M. Bradner, Amber Moser, Chelsea A. Rickman, Zachary T. McEachin, Megan M. Merritt, Jason M. Hansen, W. Michael Caudle
Published 2015-05-01

Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis

by Nisha Raj, Zachary T. McEachin, William Harousseau, Ying Zhou, Feiran Zhang, Megan E. Merritt-Garza, J. Matthew Taliaferro, Magdalena Kalinowska, Samuele G. Marro, Chadwick M. Hales, Elizabeth Berry-Kravis, Marisol W. Wolf-Ochoa, Veronica Martinez-Cerdeño, Marius Wernig, Lu Chen, Eric Klann, Stephen T. Warren, Peng Jin, Zhexing Wen, Gary J. Bassell
Published 2021-04-01

The M1311V variant of ATP7A is associated with impaired trafficking and copper homeostasis in models of motor neuron disease

by Nadine Bakkar, Alexander Starr, Benjamin E. Rabichow, Ileana Lorenzini, Zachary T. McEachin, Robert Kraft, Matthew Chaung, Sam Macklin-Isquierdo, Taylor Wingfield, Briggs Carhart, Nathan Zahler, Wen-Hsuan Chang, Gary J. Bassell, Alexandre Betourne, Nicholas Boulis, Samuel V. Alworth, Justin K. Ichida, Paul R. August, Daniela C. Zarnescu, Rita Sattler, Robert Bowser
Published 2021-02-01

Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo

by Tiffany W. Todd, Zachary T. McEachin, Jeannie Chew, Alexander R. Burch, Karen Jansen-West, Jimei Tong, Mei Yue, Yuping Song, Monica Castanedes-Casey, Aishe Kurti, Judith H. Dunmore, John D. Fryer, Yong-Jie Zhang, Beatriz San Millan, Susana Teijeira Bautista, Manuel Arias, Dennis Dickson, Tania F. Gendron, María-Jesús Sobrido, Matthew D. Disney, Gary J. Bassell, Wilfried Rossoll, Leonard Petrucelli
Published 2020-05-01