Fecal microbiota transplantation as a mean of overcoming immunotherapy-resistant cancers – hype or hope?

by Erez N. Baruch, Tanmay Gaglani, Jennifer A. Wargo
Published 2021-09-01

Concepts Collide: Genomic, Immune, and Microbial Influences on the Tumor Microenvironment and Response to Cancer Therapy

by Miles C. Andrews, Miles C. Andrews, Miles C. Andrews, Alexandre Reuben, Vancheswaran Gopalakrishnan, Jennifer A. Wargo, Jennifer A. Wargo
Published 2018-05-01

Combining targeted therapy and immune checkpoint inhibitors in the treatment of metastatic melanoma

by Teresa Kim, Rodabe N. Amaria, Christine Spencer, Alexandre Reuben, Zachary A. Cooper, Jennifer A. Wargo
Published 2014-12-01

High expression of PD-1 and PD-L1 in ocular adnexal sebaceous carcinoma

by Thomas J. Kandl, Oded Sagiv, Jonathan L. Curry, Jing Ning, Junsheng Ma, Courtney W. Hudgens, John Van Arnam, Jennifer A. Wargo, Bita Esmaeli, Michael T. Tetzlaff
Published 2018-09-01

Resolution of tissue signatures of therapy response in patients with recurrent GBM treated with neoadjuvant anti-PD1

by Yue Lu, Alphonsus H. C. Ng, Frances E. Chow, Richard G. Everson, Beth A. Helmink, Michael T. Tetzlaff, Rohit Thakur, Jennifer A. Wargo, Timothy F. Cloughesy, Robert M. Prins, James R. Heath
Published 2021-06-01

Granulomatous/sarcoid-like lesions associated with checkpoint inhibitors: a marker of therapy response in a subset of melanoma patients

by Michael T. Tetzlaff, Kelly C. Nelson, Adi Diab, Gregg A. Staerkel, Priyadharsini Nagarajan, Carlos A. Torres-Cabala, Beth A. Chasen, Jennifer A. Wargo, Victor G. Prieto, Rodabe N. Amaria, Jonathan L. Curry
Published 2018-02-01

Analysis of the immune infiltrate in undifferentiated pleomorphic sarcoma of the extremity and trunk in response to radiotherapy: Rationale for combination neoadjuvant immune check...

by Emily Z. Keung, Jen-Wei Tsai, Ali M. Ali, Janice N. Cormier, Andrew J. Bishop, B. Ashleigh Guadagnolo, Keila E. Torres, Neeta Somaiah, Kelly K. Hunt, Jennifer A. Wargo, Alexander J. Lazar, Wei-Lien Wang, Christina L. Roland
Published 2018-02-01

A phase II study of combined therapy with a BRAF inhibitor (vemurafenib) and interleukin-2 (aldesleukin) in patients with metastatic melanoma

by Meghan J. Mooradian, Alexandre Reuben, Peter A. Prieto, Mehlika Hazar-Rethinam, Dennie T. Frederick, Brandon Nadres, Adriano Piris, Vikram Juneja, Zachary A. Cooper, Arlene H. Sharpe, Ryan B. Corcoran, Keith T. Flaherty, Donald P. Lawrence, Jennifer A. Wargo, Ryan J. Sullivan
Published 2018-05-01

Comparative immunologic characterization of autoimmune giant cell myocarditis with ipilimumab

by Alexandre Reuben, Mariana Petaccia de Macedo, Jennifer McQuade, Aron Joon, Zhiyong Ren, Tiffany Calderone, Brandy Conner, Khalida Wani, Zachary A. Cooper, Hussein Tawbi, Michael T. Tetzlaff, Robert F. Padera, Jean-Bernard Durand, Alexander J. Lazar, Jennifer A. Wargo, Michael A. Davies
Published 2017-12-01

Expression of PD-1 and PD-L1 in Extramammary Paget Disease: Implications for Immune-Targeted Therapy

by Shakuntala H. Mauzo, Michael T. Tetzlaff, Denái R. Milton, Alan E. Siroy, Priyadharsini Nagarajan, Carlos A. Torres-Cabala, Doina Ivan, Jonathan L. Curry, Courtney W. Hudgens, Jennifer A. Wargo, Aysegul A. Sahin, Curtis A. Pettaway, Victor G. Prieto, Phyu P. Aung
Published 2019-05-01

Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment.

by Adam A Friedman, Arnaud Amzallag, Iulian Pruteanu-Malinici, Subash Baniya, Zachary A Cooper, Adriano Piris, Leeza Hargreaves, Vivien Igras, Dennie T Frederick, Donald P Lawrence, Daniel A Haber, Keith T Flaherty, Jennifer A Wargo, Sridhar Ramaswamy, Cyril H Benes, David E Fisher
Published 2015-01-01

Phase II study of neoadjuvant checkpoint blockade in patients with surgically resectable undifferentiated pleomorphic sarcoma and dedifferentiated liposarcoma

by Emily Z. Keung, Alexander J. Lazar, Keila E. Torres, Wei-Lien Wang, Janice N. Cormier, B. Ashleigh Guadagnolo, Andrew J. Bishop, Heather Lin, Kelly K. Hunt, Justin Bird, Valerae O. Lewis, Shreyaskumar R. Patel, Jennifer A. Wargo, Neeta Somaiah, Christina L. Roland
Published 2018-09-01

Clinical profiling of BCL-2 family members in the setting of BRAF inhibition offers a rationale for targeting de novo resistance using BH3 mimetics.

by Dennie T Frederick, Roberto A Salas Fragomeni, Aislyn Schalck, Isabel Ferreiro-Neira, Taylor Hoff, Zachary A Cooper, Rizwan Haq, David J Panka, Lawrence N Kwong, Michael A Davies, James C Cusack, Keith T Flaherty, David E Fisher, James W Mier, Jennifer A Wargo, Ryan J Sullivan
Published 2014-01-01

Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation

by Hyungsoo Kim, Dennie T. Frederick, Mitchell P. Levesque, Zachary A. Cooper, Yongmei Feng, Clemens Krepler, Laurence Brill, Yardena Samuels, Nicholas K. Hayward, Ally Perlina, Adriano Piris, Tongwu Zhang, Ruth Halaban, Meenhard M. Herlyn, Kevin M. Brown, Jennifer A. Wargo, Reinhard Dummer, Keith T. Flaherty, Ze’ev A. Ronai
Published 2015-06-01

Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma

by Elena Galvani, Piyushkumar A. Mundra, Sara Valpione, Pablo Garcia-Martinez, Matthew Smith, Jonathan Greenall, Rohit Thakur, Beth Helmink, Miles C. Andrews, Louis Boon, Christopher Chester, Gabriela Gremel, Kate Hogan, Amit Mandal, Kang Zeng, Antonia Banyard, Garry Ashton, Martin Cook, Paul Lorigan, Jennifer A. Wargo, Nathalie Dhomen, Richard Marais
Published 2020-02-01

Implementation of a Pan-Genomic Approach to Investigate Holobiont-Infecting Microbe Interaction: A Case Report of a Leukemic Patient with Invasive Mucormycosis.

by Samuel A Shelburne, Nadim J Ajami, Marcus C Chibucos, Hannah C Beird, Jeffrey Tarrand, Jessica Galloway-Peña, Nathan Albert, Roy F Chemaly, Shashank S Ghantoji, Lisa Marsh, Naveen Pemmaraju, Michael Andreeff, Elizabeth J Shpall, Jennifer A Wargo, Katayoun Rezvani, Amin Alousi, Vincent M Bruno, Phillip A Futreal, Joseph F Petrosino, Dimitrios P Kontoyiannis
Published 2015-01-01

Future perspectives in melanoma research “Melanoma Bridge”, Napoli, November 30th–3rd December 2016

by Paolo A. Ascierto, Sanjiv S. Agarwala, Gennaro Ciliberto, Sandra Demaria, Reinhard Dummer, Connie P. M. Duong, Soldano Ferrone, Silvia C. Formenti, Claus Garbe, Ruth Halaban, Samir Khleif, Jason J. Luke, Lluis M. Mir, Willem W. Overwijk, Michael Postow, Igor Puzanov, Paul Sondel, Janis M. Taube, Per Thor Straten, David F. Stroncek, Jennifer A. Wargo, Hassane Zarour, Magdalena Thurin
Published 2017-11-01

Parallel profiling of immune infiltrate subsets in uveal melanoma versus cutaneous melanoma unveils similarities and differences: A pilot study

by Yong Qin, Mariana Petaccia de Macedo, Alexandre Reuben, Marie-Andrée Forget, Cara Haymaker, Chantale Bernatchez, Christine N. Spencer, Vancheswaran Gopalakrishnan, Sujan Reddy, Zachary A. Cooper, Orenthial J. Fulbright, Renjith Ramachandran, Arely Wahl, Esteban Flores, Shawne T. Thorsen, Rene J. Tavera, Claudius Conrad, Michelle D. Williams, Michael T. Tetzlaff, Wei-Lien Wang, Dan S. Gombos, Bita Esmaeli, Rodabe N. Amaria, Patrick Hwu, Jennifer A. Wargo, Alexander J. Lazar, Sapna P. Patel
Published 2017-06-01

Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer

by Tina Cascone, Annikka Weissferdt, Myrna C. B. Godoy, William N. William, Cheuk H. Leung, Heather Y. Lin, Sreyashi Basu, Shalini S. Yadav, Apar Pataer, Kyle G. Mitchell, Md Abdul Wadud Khan, Yushu Shi, Cara Haymaker, Luisa M. Solis, Edwin R. Parra, Humam Kadara, Ignacio I. Wistuba, Padmanee Sharma, James P. Allison, Nadim J. Ajami, Jennifer A. Wargo, Robert R. Jenq, Don L. Gibbons, J. Jack Lee, Stephen G. Swisher, Ara A. Vaporciyan, John V. Heymach, Boris Sepesi
Published 2021-08-01

Future perspectives in melanoma research

by Paolo A. Ascierto, Sanjiv Agarwala, Gerardo Botti, Alessandra Cesano, Gennaro Ciliberto, Michael A. Davies, Sandra Demaria, Reinhard Dummer, Alexander M. Eggermont, Soldano Ferrone, Yang Xin Fu, Thomas F. Gajewski, Claus Garbe, Veronica Huber, Samir Khleif, Michael Krauthammer, Roger S. Lo, Giuseppe Masucci, Giuseppe Palmieri, Michael Postow, Igor Puzanov, Ann Silk, Stefani Spranger, David F. Stroncek, Ahmad Tarhini, Janis M. Taube, Alessandro Testori, Ena Wang, Jennifer A. Wargo, Cassian Yee, Hassane Zarour, Laurence Zitvogel, Bernard A. Fox, Nicola Mozzillo, Francesco M. Marincola, Magdalena Thurin
Published 2016-11-01