Soluble interleukin-15 complexes are generated in vivo by type I interferon dependent and independent pathways.

by Scott M Anthony, Megan E Howard, Yared Hailemichael, Willem W Overwijk, Kimberly S Schluns
Published 2015-01-01

The immune system in cancer metastasis: friend or foe?

by Louise M.E. Janssen, Emma E. Ramsay, Craig D. Logsdon, Willem W. Overwijk
Published 2017-10-01

Characterization of the Inflammatory Microenvironment and Identification of Potential Therapeutic Targets in Wilms Tumors

by Paramahamsa Maturu, Willem W. Overwijk, John Hicks, Suhendan Ekmekcioglu, Elizabeth A. Grimm, Vicki Huff
Published 2014-08-01

Immune cell profiling in cancer: molecular approaches to cell-specific identification

by Yasmin A. Lyons, Sherry Y. Wu, Willem W. Overwijk, Keith A. Baggerly, Anil K. Sood
Published 2017-08-01

Role of Cyclooxygenase-2 Pathway in Creating an Immunosuppressive Microenvironment and in Initiation and Progression of Wilms' Tumor

by Paramahamsa Maturu, Devin Jones, E. Cristy Ruteshouser, Qianghua Hu, Joseph M Reynolds, John Hicks, Nagireddy Putluri, Suhendan Ekmekcioglu, Elizabeth A. Grimm, Chen Dong, Willem W Overwijk
Published 2017-03-01

Combination of radiation therapy, bempegaldesleukin, and checkpoint blockade eradicates advanced solid tumors and metastases in mice

by Willem W Overwijk, Zachary S Morris, Paul M Sondel, Deborah H Charych, Amy K Erbe, Jacquelyn A Hank, Alexander L Rakhmilevich, Won Jong Jin, Peter M Carlson, Alexander A Pieper, Ravi B Patel, Daniel V Spiegelman, Jen Birstler
Published 2021-06-01

Absence of Grail promotes CD8+ T cell anti-tumour activity

by Cara Haymaker, Yi Yang, Junmei Wang, Qiang Zou, Anupama Sahoo, Andrei Alekseev, Divyendu Singh, Krit Ritthipichai, Yared Hailemichael, Oanh N. Hoang, Hong Qin, Kimberly S. Schluns, Tiejun Wang, Willem W. Overwijk, Shao-Cong Sun, Chantale Bernatchez, Larry W. Kwak, Sattva S. Neelapu, Roza Nurieva
Published 2017-08-01

Intratumoral CD40 activation and checkpoint blockade induces T cell-mediated eradication of melanoma in the brain

by Manisha Singh, Christina Vianden, Mark J. Cantwell, Zhimin Dai, Zhilan Xiao, Meenu Sharma, Hiep Khong, Ashvin R. Jaiswal, Faisal Faak, Yared Hailemichael, L. M. E. Janssen, Uddalak Bharadwaj, Michael A. Curran, Adi Diab, Roland L. Bassett, David J. Tweardy, Patrick Hwu, Willem W. Overwijk
Published 2017-11-01

Future perspectives in melanoma research “Melanoma Bridge”, Napoli, November 30th–3rd December 2016

by Paolo A. Ascierto, Sanjiv S. Agarwala, Gennaro Ciliberto, Sandra Demaria, Reinhard Dummer, Connie P. M. Duong, Soldano Ferrone, Silvia C. Formenti, Claus Garbe, Ruth Halaban, Samir Khleif, Jason J. Luke, Lluis M. Mir, Willem W. Overwijk, Michael Postow, Igor Puzanov, Paul Sondel, Janis M. Taube, Per Thor Straten, David F. Stroncek, Jennifer A. Wargo, Hassane Zarour, Magdalena Thurin
Published 2017-11-01

Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy

by Meenu Sharma, Hiep Khong, Faisal Fa’ak, Salah-Eddine Bentebibel, Louise M. E. Janssen, Brent C. Chesson, Caitlin A. Creasy, Marie-Andrée Forget, Laura Maria S. Kahn, Barbara Pazdrak, Binisha Karki, Yared Hailemichael, Manisha Singh, Christina Vianden, Srinivas Vennam, Uddalak Bharadwaj, David J. Tweardy, Cara Haymaker, Chantale Bernatchez, Shixia Huang, Kimal Rajapakshe, Cristian Coarfa, Michael E. Hurwitz, Mario Sznol, Patrick Hwu, Ute Hoch, Murali Addepalli, Deborah H. Charych, Jonathan Zalevsky, Adi Diab, Willem W. Overwijk
Published 2020-01-01