Bi-epitope SPR surfaces: a solution to develop robust immunoassays.

by Li Peng, Melissa M Damschroder, Herren Wu, William F Dall'Acqua
Published 2014-01-01

Development of a fluorescent reporter system for monitoring ER stress in Chinese hamster ovary cells and its application for therapeutic protein production.

by Gargi Roy, Shu Zhang, Lina Li, Eileen Higham, Herren Wu, Marcello Marelli, Michael A Bowen
Published 2017-01-01

Characterization and in vitro data of antibody drug conjugates (ADCs) derived from heterotrifunctional linker designed for the site-specific preparation of dual ADCs

by Amit Kumar, Krista Kinneer, Luke Masterson, Ebele Ezeadi, Philip Howard, Herren Wu, Changshou Gao, Nazzareno Dimasi
Published 2018-12-01

Enhancement of Immune Effector Functions by Modulating IgG's Intrinsic Affinity for Target Antigen.

by Yariv Mazor, Chunning Yang, M Jack Borrok, Joanne Ayriss, Karen Aherne, Herren Wu, William F Dall'Acqua
Published 2016-01-01

Controlled Fab installation onto polymeric micelle nanoparticles for tuned bioactivity

by Shaoyi Chen, Stelios Florinas, Abigail Teitgen, Ze-Qi Xu, Changshou Gao, Herren Wu, Kazunori Kataoka, Horacio Cabral, R. James Christie
Published 2017-12-01

A Novel Dual Expression Platform for High Throughput Functional Screening of Phage Libraries in Product like Format.

by Xiaodong Xiao, Yan Chen, Sheila Mugabe, Changshou Gao, Christine Tkaczyk, Yariv Mazor, Peter Pavlik, Herren Wu, William Dall'Acqua, Partha Sarathi Chowdhury
Published 2015-01-01

Generation and Characterization of an IgG4 Monomeric Fc Platform.

by Lu Shan, Magali Colazet, Kim L Rosenthal, Xiang-Qing Yu, Jared S Bee, Andrew Ferguson, Melissa M Damschroder, Herren Wu, William F Dall'Acqua, Ping Tsui, Vaheh Oganesyan
Published 2016-01-01

Correction: Upregulation of annexin A1 protein expression in the intratumoral vasculature of human non-small-cell lung carcinoma and rodent tumor models.

by Kevin L Allen, Jennifer Cann, Weiguang Zhao, Norman Peterson, Michelle Lazzaro, Haihong Zhong, Herren Wu, William F Dall'Acqua, M Jack Borrok, Melissa M Damschroder, Ping Tsui, Qing Li
Published 2021-01-01

Upregulation of annexin A1 protein expression in the intratumoral vasculature of human non-small-cell lung carcinoma and rodent tumor models.

by Kevin L Allen, Jennifer Cann, Weiguang Zhao, Norman Peterson, Michelle Lazzaro, Haihong Zhong, Herren Wu, William F Dall'Acqua, M Jack Borrok, Melissa M Damschroder, Ping Tsui, Qing Li
Published 2020-01-01

Discovery and characterization of potent IL-21 neutralizing antibodies via a novel alternating antigen immunization and humanization strategy.

by Reena Varkey, Qun Du, Jodi L Karnell, Xiaodong Xiao, Kerry A Casey, Rob Woods, Kim Rosenthal, Susan Wilson, William F Dall'Acqua, Herren Wu, Ronald Herbst, Rachel Ettinger, Melissa Damschroder
Published 2019-01-01

Anti-MrkA Monoclonal Antibodies Reveal Distinct Structural and Antigenic Features of MrkA.

by Qun Wang, Yan Chen, Romana Cvitkovic, Meghan E Pennini, Chew Shun Chang, Mark Pelletier, Jessica Bonnell, Adem C Koksal, Herren Wu, William F Dall'Acqua, C Kendall Stover, Xiaodong Xiao
Published 2017-01-01

The CEA/CD3-bispecific antibody MEDI-565 (MT111) binds a nonlinear epitope in the full-length but not a short splice variant of CEA.

by Li Peng, Michael D Oberst, Jiaqi Huang, Philip Brohawn, Chris Morehouse, Kristen Lekstrom, Patrick A Baeuerle, Herren Wu, Yihong Yao, Steven R Coats, William Dall'Acqua, Melissa Damschroder, Scott A Hammond
Published 2012-01-01

Pyrrolobenzodiazepine Antibody-Drug Conjugates Designed for Stable Thiol Conjugation

by R. James Christie, Arnaud C. Tiberghien, Qun Du, Binyam Bezabeh, Ryan Fleming, Amanda Shannon, Shenlan Mao, Shannon Breen, Jing Zhang, Haihong Zhong, Jay Harper, Herren Wu, Philip W. Howard, Changshou Gao
Published 2017-11-01

In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance

by Lu Shan, Nydia Van Dyk, Nantaporn Haskins, Kimberly M. Cook, Kim L. Rosenthal, Ronit Mazor, Sonia Dragulin-Otto, Yu Jiang, Herren Wu, William F. Dall’Acqua, Martin J. Borrok, Melissa M. Damschroder, Vaheh Oganesyan
Published 2021-09-01

Antibody-Dependent Cell-Mediated Cytotoxicity Effector-Enhanced EphA2 Agonist Monoclonal Antibody Demonstrates Potent Activity against Human Tumors

by Elizabeth M. Bruckheimer, Christine A. Fazenbaker, Sandra Gallagher, Kathy Mulgrew, Stacy Fuhrmann, Karen T. Coffman, William Walsh, Shannon Ready, Kim Cook, Melissa Damschroder, Michael Kinch, Peter A. Kiener, Rob Woods, Changshou Gao, William Dall'Acqua, Herren Wu, Steven Coats
Published 2009-06-01

A Therapeutic Uricase with Reduced Immunogenicity Risk and Improved Development Properties.

by Andrew C Nyborg, Chris Ward, Anna Zacco, Benoy Chacko, Luba Grinberg, James C Geoghegan, Ryan Bean, Michaela Wendeler, Frank Bartnik, Ellen O'Connor, Flaviu Gruia, Vidyashankara Iyer, Hui Feng, Varnika Roy, Mark Berge, Jeffrey N Miner, David M Wilson, Dongmei Zhou, Simone Nicholson, Clynn Wilker, Chi Y Wu, Susan Wilson, Lutz Jermutus, Herren Wu, David A Owen, Jane Osbourn, Steven Coats, Manuel Baca
Published 2016-01-01