Discovery and characterization of potent IL-21 neutralizing antibodies via a novel alternating antigen immunization and humanization strategy.

by Reena Varkey, Qun Du, Jodi L Karnell, Xiaodong Xiao, Kerry A Casey, Rob Woods, Kim Rosenthal, Susan Wilson, William F Dall'Acqua, Herren Wu, Ronald Herbst, Rachel Ettinger, Melissa Damschroder
Published 2019-01-01

The CEA/CD3-bispecific antibody MEDI-565 (MT111) binds a nonlinear epitope in the full-length but not a short splice variant of CEA.

by Li Peng, Michael D Oberst, Jiaqi Huang, Philip Brohawn, Chris Morehouse, Kristen Lekstrom, Patrick A Baeuerle, Herren Wu, Yihong Yao, Steven R Coats, William Dall'Acqua, Melissa Damschroder, Scott A Hammond
Published 2012-01-01

Antibody-Dependent Cell-Mediated Cytotoxicity Effector-Enhanced EphA2 Agonist Monoclonal Antibody Demonstrates Potent Activity against Human Tumors

by Elizabeth M. Bruckheimer, Christine A. Fazenbaker, Sandra Gallagher, Kathy Mulgrew, Stacy Fuhrmann, Karen T. Coffman, William Walsh, Shannon Ready, Kim Cook, Melissa Damschroder, Michael Kinch, Peter A. Kiener, Rob Woods, Changshou Gao, William Dall'Acqua, Herren Wu, Steven Coats
Published 2009-06-01