Generation and Characterization of an IgG4 Monomeric Fc Platform.

by Lu Shan, Magali Colazet, Kim L Rosenthal, Xiang-Qing Yu, Jared S Bee, Andrew Ferguson, Melissa M Damschroder, Herren Wu, William F Dall'Acqua, Ping Tsui, Vaheh Oganesyan
Published 2016-01-01

Experimentally guided computational antibody affinity maturation with de novo docking, modelling and rational design.

by Daniel A Cannon, Lu Shan, Qun Du, Lena Shirinian, Keith W Rickert, Kim L Rosenthal, Martin Korade, Lilian E van Vlerken-Ysla, Andrew Buchanan, Tristan J Vaughan, Melissa M Damschroder, Bojana Popovic
Published 2019-05-01

In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance

by Lu Shan, Nydia Van Dyk, Nantaporn Haskins, Kimberly M. Cook, Kim L. Rosenthal, Ronit Mazor, Sonia Dragulin-Otto, Yu Jiang, Herren Wu, William F. Dall’Acqua, Martin J. Borrok, Melissa M. Damschroder, Vaheh Oganesyan
Published 2021-09-01