Major adverse cardiovascular events in people with chronic kidney disease in relation to disease severity and diabetes status.

by Craig J Currie, Ellen R Berni, Thomas R Berni, Sara Jenkins-Jones, Marvin Sinsakul, Lutz Jermutus, Philip Ambery, Meena Jain
Published 2019-01-01

Engineering neprilysin activity and specificity to create a novel therapeutic for Alzheimer's disease.

by Carl I Webster, Matthew Burrell, Lise-Lotte Olsson, Susan B Fowler, Sarah Digby, Alan Sandercock, Arjan Snijder, Jan Tebbe, Ulrich Haupts, Joanna Grudzinska, Lutz Jermutus, Christin Andersson
Published 2014-01-01

A Therapeutic Uricase with Reduced Immunogenicity Risk and Improved Development Properties.

by Andrew C Nyborg, Chris Ward, Anna Zacco, Benoy Chacko, Luba Grinberg, James C Geoghegan, Ryan Bean, Michaela Wendeler, Frank Bartnik, Ellen O'Connor, Flaviu Gruia, Vidyashankara Iyer, Hui Feng, Varnika Roy, Mark Berge, Jeffrey N Miner, David M Wilson, Dongmei Zhou, Simone Nicholson, Clynn Wilker, Chi Y Wu, Susan Wilson, Lutz Jermutus, Herren Wu, David A Owen, Jane Osbourn, Steven Coats, Manuel Baca
Published 2016-01-01