In silico Prioritization of Transporter–Drug Relationships From Drug Sensitivity Screens

by Adrián César-Razquin, Enrico Girardi, Mi Yang, Mi Yang, Marc Brehme, Marc Brehme, Julio Saez-Rodriguez, Julio Saez-Rodriguez, Giulio Superti-Furga, Giulio Superti-Furga
Published 2018-09-01

Crystal structure of mammalian acid sphingomyelinase

by Alexei Gorelik, Katalin Illes, Leonhard X. Heinz, Giulio Superti-Furga, Bhushan Nagar
Published 2016-07-01

A computational approach to analyze the mechanism of action of the kinase inhibitor bafetinib.

by Thomas R Burkard, Uwe Rix, Florian P Breitwieser, Giulio Superti-Furga, Jacques Colinge
Published 2010-11-01

A substrate‐based ontology for human solute carriers

by Eva Meixner, Ulrich Goldmann, Vitaly Sedlyarov, Stefania Scorzoni, Manuele Rebsamen, Enrico Girardi, Giulio Superti‐Furga
Published 2020-07-01

The SH2 domain regulates c-Abl kinase activation by a cyclin-like mechanism and remodulation of the hinge motion.

by Nicole Dölker, Maria W Górna, Ludovico Sutto, Antonio S Torralba, Giulio Superti-Furga, Francesco L Gervasio
Published 2014-10-01

The transporters SLC35A1 and SLC30A1 play opposite roles in cell survival upon VSV virus infection

by Anna Moskovskich, Ulrich Goldmann, Felix Kartnig, Sabrina Lindinger, Justyna Konecka, Giuseppe Fiume, Enrico Girardi, Giulio Superti-Furga
Published 2019-07-01

eIF2B as a Target for Viral Evasion of PKR-Mediated Translation Inhibition

by Jennifer Deborah Wuerth, Matthias Habjan, Markus Kainulainen, Besim Berisha, Damien Bertheloot, Giulio Superti-Furga, Andreas Pichlmair, Friedemann Weber
Published 2020-07-01

Enhancing cognate target elution efficiency in gel-free chemical proteomics

by Branka Radic-Sarikas, Uwe Rix, Alexey Stukalov, Manuela Gridling, André C. Müller, Jacques Colinge, Giulio Superti-Furga, Keiryn L. Bennett
Published 2015-12-01

Lapatinib potentiates cytotoxicity of  YM155 in neuroblastoma via inhibition of the ABCB1 efflux transporter

by Branka Radic-Sarikas, Melinda Halasz, Kilian V. M. Huber, Georg E. Winter, Kalliopi P. Tsafou, Theodore Papamarkou, Søren Brunak, Walter Kolch, Giulio Superti-Furga
Published 2017-06-01

Functional dissection of the TBK1 molecular network.

by Adriana Goncalves, Tilmann Bürckstümmer, Evelyn Dixit, Ruth Scheicher, Maria W Górna, Evren Karayel, Cristina Sugar, Alexey Stukalov, Tiina Berg, Robert Kralovics, Melanie Planyavsky, Keiryn L Bennett, Jacques Colinge, Giulio Superti-Furga
Published 2011-01-01

IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes

by Michael Bonelli, Karolina Dalwigk, Alexander Platzer, Isabel Olmos Calvo, Silvia Hayer, Birgit Niederreiter, Johannes Holinka, Florian Sevelda, Thomas Pap, Günter Steiner, Giulio Superti-Furga, Josef S. Smolen, Hans P. Kiener, Thomas Karonitsch
Published 2019-07-01

A target-disease network model of second-generation BCR-ABL inhibitor action in Ph+ ALL.

by Uwe Rix, Jacques Colinge, Katharina Blatt, Manuela Gridling, Lily L Remsing Rix, Katja Parapatics, Sabine Cerny-Reiterer, Thomas R Burkard, Ulrich Jäger, Junia V Melo, Keiryn L Bennett, Peter Valent, Giulio Superti-Furga
Published 2013-01-01

Common Nodes of Virus–Host Interaction Revealed Through an Integrated Network Analysis

by Korbinian Bösl, Korbinian Bösl, Aleksandr Ianevski, Thoa T. Than, Petter I. Andersen, Suvi Kuivanen, Mona Teppor, Eva Zusinaite, Uga Dumpis, Astra Vitkauskiene, Rebecca J. Cox, Hannimari Kallio-Kokko, Anders Bergqvist, Tanel Tenson, Andres Merits, Valentyn Oksenych, Magnar Bjørås, Marit W. Anthonsen, David Shum, Mari Kaarbø, Olli Vapalahti, Marc P. Windisch, Giulio Superti-Furga, Giulio Superti-Furga, Berend Snijder, Denis Kainov, Denis Kainov, Richard K. Kandasamy, Richard K. Kandasamy, Richard K. Kandasamy, Richard K. Kandasamy
Published 2019-10-01

An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of Transporters

by Vojtech Dvorak, Tabea Wiedmer, Alvaro Ingles-Prieto, Patrick Altermatt, Helena Batoulis, Felix Bärenz, Eckhard Bender, Daniela Digles, Franz Dürrenberger, Laura H. Heitman, Adriaan P. IJzerman, Douglas B. Kell, Douglas B. Kell, Stefanie Kickinger, Daniel Körzö, Philipp Leippe, Thomas Licher, Vania Manolova, Riccardo Rizzetto, Francesca Sassone, Lia Scarabottolo, Avner Schlessinger, Vanessa Schneider, Hubert J. Sijben, Anna-Lena Steck, Hanna Sundström, Sara Tremolada, Maria Wilhelm, Marina Wright Muelas, Diana Zindel, Claire M. Steppan, Giulio Superti-Furga, Giulio Superti-Furga
Published 2021-08-01

Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import

by Enrico Girardi, Gennaro Agrimi, Ulrich Goldmann, Giuseppe Fiume, Sabrina Lindinger, Vitaly Sedlyarov, Ismet Srndic, Bettina Gürtl, Benedikt Agerer, Felix Kartnig, Pasquale Scarcia, Maria Antonietta Di Noia, Eva Liñeiro, Manuele Rebsamen, Tabea Wiedmer, Andreas Bergthaler, Luigi Palmieri, Giulio Superti-Furga
Published 2020-12-01

MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity

by Anna Skucha, Jessica Ebner, Johannes Schmöllerl, Mareike Roth, Thomas Eder, Adrián César-Razquin, Alexey Stukalov, Sarah Vittori, Matthias Muhar, Bin Lu, Martin Aichinger, Julian Jude, André C. Müller, Balázs Győrffy, Christopher R. Vakoc, Peter Valent, Keiryn L. Bennett, Johannes Zuber, Giulio Superti-Furga, Florian Grebien
Published 2018-05-01

Interactome of Two Diverse RNA Granules Links mRNA Localization to Translational Repression in Neurons

by Renate Fritzsche, Daniela Karra, Keiryn L. Bennett, Foong yee Ang, Jacki E. Heraud-Farlow, Marco Tolino, Michael Doyle, Karl E. Bauer, Sabine Thomas, Melanie Planyavsky, Eric Arn, Anetta Bakosova, Kerstin Jungwirth, Alexandra Hörmann, Zsofia Palfi, Julia Sandholzer, Martina Schwarz, Paolo Macchi, Jacques Colinge, Giulio Superti-Furga, Michael A. Kiebler
Published 2013-12-01

Proposed Terminology and Classification of Pre-Malignant Neoplastic Conditions: A Consensus Proposal

by Peter Valent, Cem Akin, Michel Arock, Christoph Bock, Tracy I. George, Stephen J. Galli, Jason Gotlib, Torsten Haferlach, Gregor Hoermann, Olivier Hermine, Ulrich Jäger, Lukas Kenner, Hans Kreipe, Ravindra Majeti, Dean D. Metcalfe, Alberto Orfao, Andreas Reiter, Wolfgang R. Sperr, Philipp B. Staber, Karl Sotlar, Charles Schiffer, Giulio Superti-Furga, Hans-Peter Horny
Published 2017-12-01

The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity

by Leonhard X. Heinz, Christoph L. Baumann, Marielle S. Köberlin, Berend Snijder, Riem Gawish, Guanghou Shui, Omar Sharif, Irene M. Aspalter, André C. Müller, Richard K. Kandasamy, Florian P. Breitwieser, Andreas Pichlmair, Manuela Bruckner, Manuele Rebsamen, Stephan Blüml, Thomas Karonitsch, Astrid Fauster, Jacques Colinge, Keiryn L. Bennett, Sylvia Knapp, Markus R. Wenk, Giulio Superti-Furga
Published 2015-06-01

Precision Medicine in Hematology 2021: Definitions, Tools, Perspectives, and Open Questions

by Peter Valent, Alberto Orfao, Stefan Kubicek, Philipp Staber, Torsten Haferlach, Michael Deininger, Karoline Kollmann, Thomas Lion, Irene Virgolini, Georg Winter, Oliver Hantschel, Lukas Kenner, Johannes Zuber, Florian Grebien, Richard Moriggl, Gregor Hoermann, Olivier Hermine, Michael Andreeff, Christoph Bock, Tariq Mughal, Stefan N. Constantinescu, Robert Kralovics, Veronika Sexl, Radek Skoda, Giulio Superti-Furga, Ulrich Jäger
Published 2021-03-01