N-glycosylation in the Pre-Membrane Protein Is Essential for the Zika Virus Life Cycle

by Yong-Dae Gwon, Eva Zusinaite, Andres Merits, Anna K. Överby, Magnus Evander
Published 2020-08-01

1,3-Thiazolbenzamide Derivatives as Chikungunya Virus nsP2 Protease Inhibitors

by Larisa Ivanova, Kai Rausalu, Eva Žusinaite, Jaana Tammiku-Taul, Andres Merits, Mati Karelson
Published 2021-02-01

Active Components of Commonly Prescribed Medicines Affect Influenza A Virus–Host Cell Interaction: A Pilot Study

by Aleksandr Ianevski, Rouan Yao, Eva Zusinaite, Hilde Lysvand, Valentyn Oksenych, Tanel Tenson, Magnar Bjørås, Denis Kainov
Published 2021-08-01

Nafamostat–Interferon-α Combination Suppresses SARS-CoV-2 Infection In Vitro and In Vivo by Cooperatively Targeting Host TMPRSS2

by Aleksandr Ianevski, Rouan Yao, Hilde Lysvand, Gunnveig Grødeland, Nicolas Legrand, Valentyn Oksenych, Eva Zusinaite, Tanel Tenson, Magnar Bjørås, Denis E. Kainov
Published 2021-09-01

RNA Interference-Guided Targeting of Hepatitis C Virus Replication with Antisense Locked Nucleic Acid-Based Oligonucleotides Containing 8-oxo-dG Modifications.

by Margit Mutso, Andrei Nikonov, Arno Pihlak, Eva Žusinaite, Liane Viru, Anastasia Selyutina, Tõnu Reintamm, Merike Kelve, Mart Saarma, Mati Karelson, Andres Merits
Published 2015-01-01

A new high-content screening assay of the entire hepatitis B virus life cycle identifies novel antivirals

by Jaewon Yang, Alexander König, Soonju Park, Eunji Jo, Pil Soo Sung, Seung Kew Yoon, Eva Zusinaite, Denis Kainov, David Shum, Marc Peter Windisch
Published 2021-08-01

A Systems Approach to Study Immuno- and Neuro-Modulatory Properties of Antiviral Agents

by Eva Zusinaite, Aleksandr Ianevski, Diana Niukkanen, Minna M. Poranen, Magnar Bjørås, Jan Egil Afset, Tanel Tenson, Vidya Velagapudi, Andres Merits, Denis E. Kainov
Published 2018-08-01

Novel Antiviral Activities of Obatoclax, Emetine, Niclosamide, Brequinar, and Homoharringtonine

by Petter I. Andersen, Klara Krpina, Aleksandr Ianevski, Nastassia Shtaida, Eunji Jo, Jaewon Yang, Sandra Koit, Tanel Tenson, Veijo Hukkanen, Marit W. Anthonsen, Magnar Bjoras, Magnus Evander, Marc P. Windisch, Eva Zusinaite, Denis E. Kainov
Published 2019-10-01

Long-Term Elevated Inflammatory Protein Levels in Asymptomatic SARS-CoV-2 Infected Individuals

by Liina Tserel, Piia Jõgi, Piia Jõgi, Paul Naaber, Paul Naaber, Julia Maslovskaja, Annika Häling, Ahto Salumets, Eva Zusinaite, Hiie Soeorg, Freddy Lättekivi, Freddy Lättekivi, Diana Ingerainen, Mari Soots, Karolin Toompere, Katrin Kaarna, Katrin Kaarna, Kai Kisand, Irja Lutsar, Pärt Peterson
Published 2021-09-01

Low Temperature and Low UV Indexes Correlated with Peaks of Influenza Virus Activity in Northern Europe during 2010–2018

by Aleksandr Ianevski, Eva Zusinaite, Nastassia Shtaida, Hannimari Kallio-Kokko, Miia Valkonen, Anu Kantele, Kaidi Telling, Irja Lutsar, Pille Letjuka, Natalja Metelitsa, Valentyn Oksenych, Uga Dumpis, Astra Vitkauskiene, Kestutis Stašaitis, Christina Öhrmalm, Kåre Bondeson, Anders Bergqvist, Rebecca J. Cox, Tanel Tenson, Andres Merits, Denis E. Kainov
Published 2019-03-01

Potential Antiviral Options against SARS-CoV-2 Infection

by Aleksandr Ianevski, Rouan Yao, Mona Høysæter Fenstad, Svetlana Biza, Eva Zusinaite, Tuuli Reisberg, Hilde Lysvand, Kirsti Løseth, Veslemøy Malm Landsem, Janne Fossum Malmring, Valentyn Oksenych, Sten Even Erlandsen, Per Arne Aas, Lars Hagen, Caroline H. Pettersen, Tanel Tenson, Jan Egil Afset, Svein Arne Nordbø, Magnar Bjørås, Denis E. Kainov
Published 2020-06-01

Identification and Tracking of Antiviral Drug Combinations

by Aleksandr Ianevski, Rouan Yao, Svetlana Biza, Eva Zusinaite, Andres Mannik, Gaily Kivi, Anu Planken, Kristiina Kurg, Eva-Maria Tombak, Mart Ustav, Nastassia Shtaida, Evgeny Kulesskiy, Eunji Jo, Jaewon Yang, Hilde Lysvand, Kirsti Løseth, Valentyn Oksenych, Per Arne Aas, Tanel Tenson, Astra Vitkauskienė, Marc P. Windisch, Mona Høysæter Fenstad, Svein Arne Nordbø, Mart Ustav, Magnar Bjørås, Denis E. Kainov
Published 2020-10-01

Chemical, Physical and Biological Triggers of Evolutionary Conserved Bcl-xL-mediated Apoptosis

by Aleksandr Ianevski, Evgeny Kulesskiy, Klara Krpina, Guofeng Lou, Yahyah Aman, Andrii Bugai, Koit Aasumets, Yevhen Akimov, Daria Bulanova, Kiira Gildemann, Albert F. Arutyunyan, Olga Yu. Susova, Alexei L. Zhuze, Ping Ji, Wei Wang, Toril Holien, Marit Bugge, Eva Zusinaite, Valentyn Oksenych, Hilde Lysvand, Joachim M. Gerhold, Magnar Bjørås, Pål Johansen, Anders Waage, Caroline A. Heckman, Evandro F. Fang, Denis E. Kainov
Published 2020-06-01

Common Nodes of Virus–Host Interaction Revealed Through an Integrated Network Analysis

by Korbinian Bösl, Korbinian Bösl, Aleksandr Ianevski, Thoa T. Than, Petter I. Andersen, Suvi Kuivanen, Mona Teppor, Eva Zusinaite, Uga Dumpis, Astra Vitkauskiene, Rebecca J. Cox, Hannimari Kallio-Kokko, Anders Bergqvist, Tanel Tenson, Andres Merits, Valentyn Oksenych, Magnar Bjørås, Marit W. Anthonsen, David Shum, Mari Kaarbø, Olli Vapalahti, Marc P. Windisch, Giulio Superti-Furga, Giulio Superti-Furga, Berend Snijder, Denis Kainov, Denis Kainov, Richard K. Kandasamy, Richard K. Kandasamy, Richard K. Kandasamy, Richard K. Kandasamy
Published 2019-10-01

A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research.

by Suzannah J Rihn, Andres Merits, Siddharth Bakshi, Matthew L Turnbull, Arthur Wickenhagen, Akira J T Alexander, Carla Baillie, Benjamin Brennan, Fiona Brown, Kirstyn Brunker, Steven R Bryden, Kerry A Burness, Stephen Carmichael, Sarah J Cole, Vanessa M Cowton, Paul Davies, Chris Davis, Giuditta De Lorenzo, Claire L Donald, Mark Dorward, James I Dunlop, Matthew Elliott, Mazigh Fares, Ana da Silva Filipe, Joseph R Freitas, Wilhelm Furnon, Rommel J Gestuveo, Anna Geyer, Daniel Giesel, Daniel M Goldfarb, Nicola Goodman, Rory Gunson, C James Hastie, Vanessa Herder, Joseph Hughes, Clare Johnson, Natasha Johnson, Alain Kohl, Karen Kerr, Hannah Leech, Laura Sandra Lello, Kathy Li, Gauthier Lieber, Xiang Liu, Rajendra Lingala, Colin Loney, Daniel Mair, Marion J McElwee, Steven McFarlane, Jenna Nichols, Kyriaki Nomikou, Anne Orr, Richard J Orton, Massimo Palmarini, Yasmin A Parr, Rute Maria Pinto, Samantha Raggett, Elaine Reid, David L Robertson, Jamie Royle, Natalia Cameron-Ruiz, James G Shepherd, Katherine Smollett, Douglas G Stewart, Meredith Stewart, Elena Sugrue, Agnieszka M Szemiel, Aislynn Taggart, Emma C Thomson, Lily Tong, Leah S Torrie, Rachel Toth, Margus Varjak, Sainan Wang, Stuart G Wilkinson, Paul G Wyatt, Eva Zusinaite, Dario R Alessi, Arvind H Patel, Ali Zaid, Sam J Wilson, Suresh Mahalingam
Published 2021-02-01