Alzheimer’s disease: from basic science to precision medicine approach

by Gianluigi Forloni
Published 2020-12-01

Doxycycline for Alzheimer’s Disease: Fighting β-Amyloid Oligomers and Neuroinflammation

by Claudia Balducci, Gianluigi Forloni
Published 2019-07-01

Neuroinflammation and the Gut Microbiota: Possible Alternative Therapeutic Targets to Counteract Alzheimer’s Disease?

by Milica Cerovic, Gianluigi Forloni, Claudia Balducci
Published 2019-10-01

3D brain tissue physiological model with co-cultured primary neurons and glial cells in hydrogels

by Ilaria Raimondi, Marta Tunesi, Gianluigi Forloni, Diego Albani, Carmen Giordano
Published 2020-10-01

Cell type-specific neuroprotective activity of untranslocated prion protein.

by Elena Restelli, Luana Fioriti, Susanna Mantovani, Simona Airaghi, Gianluigi Forloni, Roberto Chiesa
Published 2010-10-01

Chemical exchange saturation transfer MRI shows low cerebral 2-deoxy-D-glucose uptake in a model of Alzheimer’s Disease

by Daniele Tolomeo, Edoardo Micotti, Sonia Colombo Serra, Michael Chappell, Anniina Snellman, Gianluigi Forloni
Published 2018-06-01

JNK regulates APP cleavage and degradation in a model of Alzheimer's disease

by Alessio Colombo, Antonio Bastone, Cristina Ploia, Alessandra Sclip, Mario Salmona, Gianluigi Forloni, Tiziana Borsello
Published 2009-03-01

DJ-1 modulates alpha-synuclein aggregation state in a cellular model of oxidative stress: relevance for Parkinson's disease and involvement of HSP70.

by Sara Batelli, Diego Albani, Raffaela Rametta, Letizia Polito, Francesca Prato, Marzia Pesaresi, Alessandro Negro, Gianluigi Forloni
Published 2008-04-01

Exome sequencing in an Italian family with Alzheimer’s disease points to a role for seizure-related gene 6 (SEZ6) rare variant R615H

by Lara Paracchini, Luca Beltrame, Lucia Boeri, Federica Fusco, Paolo Caffarra, Sergio Marchini, Diego Albani, Gianluigi Forloni
Published 2018-10-01

Comparative Magnetic Resonance Imaging and Histopathological Correlates in Two SOD1 Transgenic Mouse Models of Amyotrophic Lateral Sclerosis.

by Ilaria Caron, Edoardo Micotti, Alessandra Paladini, Giuseppe Merlino, Laura Plebani, Gianluigi Forloni, Michel Modo, Caterina Bendotti
Published 2015-01-01

The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells.

by Emiliano Biasini, Jessie A Turnbaugh, Tania Massignan, Pietro Veglianese, Gianluigi Forloni, Valentina Bonetto, Roberto Chiesa, David A Harris
Published 2012-01-01

Role of Glycogen Synthase Kinase-3β in APP Hyperphosphorylation Induced by NMDA Stimulation in Cortical Neurons

by Xanthi Antoniou, Gianluigi Forloni, Monica Di Luca, Fabrizio Gardoni, Mariaelena Repici, Alessio Colombo, Alessandra Sclip, Cristina Ploia, Tiziana Borsello
Published 2010-01-01

Sustained Delivery of Chondroitinase ABC from Hydrogel System

by Filippo Rossi, Giuseppe Perale, Maurizio Masi, Gianluigi Forloni, Valentina Dell’Oro, Simonetta Papa, Cristina Rogora, Pietro Veglianese, Marco Santoro
Published 2012-03-01

A Novel Study and Meta-Analysis of the Genetic Variation of the Serotonin Transporter Promoter in the Italian Population Do Not Support a Large Effect on Alzheimer's Disease Risk

by Letizia Polito, Francesca Prato, Serena Rodilossi, Eleonora Ateri, Daniela Galimberti, Elio Scarpini, Francesca Clerici, Claudio Mariani, Gianluigi Forloni, Diego Albani
Published 2011-01-01

The urokinase-type plasminogen activator polymorphism PLAU_1 is a risk factor for APOE-ε4 non-carriers in the Italian Alzheimer’s disease population and does not affect the plasma...

by Marzia Pesaresi, Sara Batelli, Francesca Prato, Letizia Polito, Carlo Lovati, Elio Scarpini, Pierluigi Quadri, Claudio Mariani, Diego Albani, Gianluigi Forloni
Published 2007-03-01

The efficacy of tetracyclines in peripheral and intracerebral prion infection.

by Ada De Luigi, Laura Colombo, Luisa Diomede, Raffaella Capobianco, Michela Mangieri, Claudia Miccolo, Lucia Limido, Gianluigi Forloni, Fabrizio Tagliavini, Mario Salmona
Published 2008-01-01

Hydrogel-Based Nanocomposites and Mesenchymal Stem Cells: A Promising Synergistic Strategy for Neurodegenerative Disorders Therapy

by Diego Albani, Antonio Gloria, Carmen Giordano, Serena Rodilossi, Teresa Russo, Ugo D’Amora, Marta Tunesi, Alberto Cigada, Luigi Ambrosio, Gianluigi Forloni
Published 2013-01-01

Longitudinal Molecular Magnetic Resonance Imaging of Endothelial Activation after Severe Traumatic Brain Injury

by Gloria Vegliante, Daniele Tolomeo, Antoine Drieu, Marina Rubio, Edoardo Micotti, Federico Moro, Denis Vivien, Gianluigi Forloni, Carine Ali, Elisa R. Zanier
Published 2019-07-01

Apoptotic Cell Death and Impairment of L-Type Voltage-Sensitive Calcium Channel Activity in Rat Cerebellar Granule Cells Treated with the Prion Protein Fragment 106–126

by Stefano Thellung, Tullio Florio, Valentina Villa, Alessandro Corsaro, Sara Arena, Carolina Amico, Mauro Robello, Mario Salmona, Gianluigi Forloni, Orso Bugiani, Fabrizio Tagliavini, Gennaro Schettini
Published 2000-08-01

Expression of mutant or cytosolic PrP in transgenic mice and cells is not associated with endoplasmic reticulum stress or proteasome dysfunction.

by Elena Quaglio, Elena Restelli, Anna Garofoli, Sara Dossena, Ada De Luigi, Luigina Tagliavacca, Daniele Imperiale, Antonio Migheli, Mario Salmona, Roberto Sitia, Gianluigi Forloni, Roberto Chiesa
Published 2011-04-01