Altered Metabolic Profiles Associate with Toxicity in SOD1G93A Astrocyte-Neuron Co-Cultures

by Gabriel N. Valbuena, Massimo Tortarolo, Caterina Bendotti, Lavinia Cantoni, Hector C. Keun
Published 2017-03-01

Spinal Cord Metabolic Signatures in Models of Fast- and Slow-Progressing SOD1G93A Amyotrophic Lateral Sclerosis

by Gabriel N. Valbuena, Lavinia Cantoni, Massimo Tortarolo, Caterina Bendotti, Hector C. Keun
Published 2019-12-01

Micro-computed tomography for non-invasive evaluation of muscle atrophy in mouse models of disease.

by Laura Pasetto, Davide Olivari, Giovanni Nardo, Maria Chiara Trolese, Caterina Bendotti, Rosanna Piccirillo, Valentina Bonetto
Published 2018-01-01

Comparative Magnetic Resonance Imaging and Histopathological Correlates in Two SOD1 Transgenic Mouse Models of Amyotrophic Lateral Sclerosis.

by Ilaria Caron, Edoardo Micotti, Alessandra Paladini, Giuseppe Merlino, Laura Plebani, Gianluigi Forloni, Michel Modo, Caterina Bendotti
Published 2015-01-01

The Emerging Role of the Major Histocompatibility Complex Class I in Amyotrophic Lateral Sclerosis

by Gabriela Bortolança Chiarotto, Giovanni Nardo, Maria Chiara Trolese, Marcondes Cavalcante França Jr., Caterina Bendotti, Alexandre Leite Rodrigues de Oliveira
Published 2017-11-01

Increased axonal ribosome numbers is an early event in the pathogenesis of amyotrophic lateral sclerosis.

by Mark H G Verheijen, Marco Peviani, Rita Hendricusdottir, Erin M Bell, Martin Lammens, August B Smit, Caterina Bendotti, Jan van Minnen
Published 2014-01-01

A mouse model of familial ALS has increased CNS levels of endogenous ubiquinol9/10 and does not benefit from exogenous administration of ubiquinol10.

by Jacopo Lucchetti, Marianna Marino, Simonetta Papa, Massimo Tortarolo, Giovanna Guiso, Silvia Pozzi, Valentina Bonetto, Silvio Caccia, Ettore Beghi, Caterina Bendotti, Marco Gobbi
Published 2013-01-01

Counteracting roles of MHCI and CD8+ T cells in the peripheral and central nervous system of ALS SOD1G93A mice

by Giovanni Nardo, Maria Chiara Trolese, Mattia Verderio, Alessandro Mariani, Massimiliano de Paola, Nilo Riva, Giorgia Dina, Nicolò Panini, Eugenio Erba, Angelo Quattrini, Caterina Bendotti
Published 2018-08-01

The omega-3 fatty acid eicosapentaenoic acid accelerates disease progression in a model of amyotrophic lateral sclerosis.

by Ping K Yip, Chiara Pizzasegola, Stacy Gladman, Maria Luigia Biggio, Marianna Marino, Maduka Jayasinghe, Farhan Ullah, Simon C Dyall, Andrea Malaspina, Caterina Bendotti, Adina Michael-Titus
Published 2013-01-01

A Novel HGF/SF Receptor (MET) Agonist Transiently Delays the Disease Progression in an Amyotrophic Lateral Sclerosis Mouse Model by Promoting Neuronal Survival and Dampening the Im...

by Antonio Vallarola, Massimo Tortarolo, Roberta De Gioia, Luisa Iamele, Hugo de Jonge, Giovanni de Nola, Enrica Bovio, Laura Pasetto, Valentina Bonetto, Mattia Freschi, Caterina Bendotti, Ermanno Gherardi
Published 2020-11-01

RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue

by Antonio Vallarola, Francesca Sironi, Massimo Tortarolo, Noemi Gatto, Roberta De Gioia, Laura Pasetto, Massimiliano De Paola, Alessandro Mariani, Supurna Ghosh, Richard Watson, Andreas Kalmes, Valentina Bonetto, Caterina Bendotti
Published 2018-03-01

Multiple intracerebroventricular injections of human umbilical cord mesenchymal stem cells delay motor neurons loss but not disease progression of SOD1G93A mice

by Francesca Sironi, Antonio Vallarola, Martina Bruna Violatto, Laura Talamini, Mattia Freschi, Roberta De Gioia, Chiara Capelli, Azzurra Agostini, Davide Moscatelli, Massimo Tortarolo, Paolo Bigini, Martino Introna, Caterina Bendotti
Published 2017-12-01

Amyotrophic Lateral Sclerosis, a Multisystem Pathology: Insights into the Role of TNFα

by Massimo Tortarolo, Daniele Lo Coco, Pietro Veglianese, Antonio Vallarola, Maria Teresa Giordana, Gabriella Marcon, Ettore Beghi, Marco Poloni, Michael J. Strong, Anand M. Iyer, Eleonora Aronica, Caterina Bendotti
Published 2017-01-01

Longitudinal tracking of triple labeled umbilical cord derived mesenchymal stromal cells in a mouse model of Amyotrophic Lateral Sclerosis

by Martina Bruna Violatto, Chiara Santangelo, Chiara Capelli, Roberta Frapolli, Raffaele Ferrari, Leopoldo Sitia, Massimo Tortarolo, Laura Talamini, Sara Previdi, Davide Moscatelli, Mario Salmona, Martino Introna, Caterina Bendotti, Paolo Bigini
Published 2015-07-01

CXCL13/CXCR5 signalling is pivotal to preserve motor neurons in amyotrophic lateral sclerosis

by Maria Chiara Trolese, Alessandro Mariani, Mineko Terao, Massimiliano de Paola, Paola Fabbrizio, Francesca Sironi, Mami Kurosaki, Silvia Bonanno, Silvia Marcuzzo, Pia Bernasconi, Francesca Trojsi, Eleonora Aronica, Caterina Bendotti, Giovanni Nardo
Published 2020-12-01

Creatine Kinase and Progression Rate in Amyotrophic Lateral Sclerosis

by Marco Ceccanti, Valeria Pozzilli, Chiara Cambieri, Laura Libonati, Emanuela Onesti, Vittorio Frasca, Ilenia Fiorini, Antonio Petrucci, Matteo Garibaldi, Eleonora Palma, Caterina Bendotti, Paola Fabbrizio, Maria Chiara Trolese, Giovanni Nardo, Maurizio Inghilleri
Published 2020-05-01

Tissue-enhanced plasma proteomic analysis for disease stratification in amyotrophic lateral sclerosis

by Irene Zubiri, Vittoria Lombardi, Michael Bremang, Vikram Mitra, Giovanni Nardo, Rocco Adiutori, Ching-Hua Lu, Emanuela Leoni, Ping Yip, Ozlem Yildiz, Malcolm Ward, Linda Greensmith, Caterina Bendotti, Ian Pike, Andrea Malaspina
Published 2018-11-01

Amyotrophic lateral sclerosis multiprotein biomarkers in peripheral blood mononuclear cells.

by Giovanni Nardo, Silvia Pozzi, Mauro Pignataro, Eliana Lauranzano, Giorgia Spano, Silvia Garbelli, Stefania Mantovani, Kalliopi Marinou, Laura Papetti, Marta Monteforte, Valter Torri, Luca Paris, Gianfranco Bazzoni, Christian Lunetta, Massimo Corbo, Gabriele Mora, Caterina Bendotti, Valentina Bonetto
Published 2011-01-01

Characterization of detergent-insoluble proteins in ALS indicates a causal link between nitrative stress and aggregation in pathogenesis.

by Manuela Basso, Giuseppina Samengo, Giovanni Nardo, Tania Massignan, Giuseppina D'Alessandro, Silvia Tartari, Lavinia Cantoni, Marianna Marino, Cristina Cheroni, Silvia De Biasi, Maria Teresa Giordana, Michael J Strong, Alvaro G Estevez, Mario Salmona, Caterina Bendotti, Valentina Bonetto
Published 2009-12-01

Motor neuron degeneration, severe myopathy and TDP-43 increase in a transgenic pig model of SOD1-linked familiar ALS

by Paola Crociara, Maria Novella Chieppa, Elena Vallino Costassa, Elena Berrone, Marina Gallo, Monica Lo Faro, Maria Domenica Pintore, Barbara Iulini, Antonio D'Angelo, Giovanni Perona, Alberto Botter, Donato Formicola, Alberto Rainoldi, Marianna Paulis, Paolo Vezzoni, Federica Meli, Fiorenzo Antonio Peverali, Caterina Bendotti, Maria Chiara Trolese, Laura Pasetto, Valentina Bonetto, Giovanna Lazzari, Roberto Duchi, Andrea Perota, Irina Lagutina, Corinne Quadalti, Maria Silvia Gennero, Daniela Dezzutto, Rosanna Desiato, Marina Boido, Matilde Ghibaudi, Maria Consuelo Valentini, Maria Caramelli, Cesare Galli, Cristina Casalone, Cristiano Corona
Published 2019-04-01