<i>Caenorhabditis elegans</i> Models to Investigate the Mechanisms Underlying Tau Toxicity in Tauopathies

by Carmina Natale, Maria Monica Barzago, Luisa Diomede
Published 2020-11-01

Glimepiride reduces the expression of PrPc, prevents PrPSc formation and protects against prion mediated neurotoxicity in cell lines.

by Clive Bate, Mourad Tayebi, Luisa Diomede, Mario Salmona, Alun Williams
Published 2009-12-01

Oleuropein aglycone protects transgenic C. elegans strains expressing Aβ42 by reducing plaque load and motor deficit.

by Luisa Diomede, Stefania Rigacci, Margherita Romeo, Massimo Stefani, Mario Salmona
Published 2013-01-01

Can Antiviral Activity of Licorice Help Fight COVID-19 Infection?

by Luisa Diomede, Marten Beeg, Alessio Gamba, Oscar Fumagalli, Marco Gobbi, Mario Salmona
Published 2021-06-01

Tetracycline and its analogues protect Caenorhabditis elegans from β amyloid-induced toxicity by targeting oligomers

by Luisa Diomede, Giuseppe Cassata, Fabio Fiordaliso, Monica Salio, Diletta Ami, Antonino Natalello, Silvia Maria Doglia, Ada De Luigi, Mario Salmona
Published 2010-11-01

The efficacy of tetracyclines in peripheral and intracerebral prion infection.

by Ada De Luigi, Laura Colombo, Luisa Diomede, Raffaella Capobianco, Michela Mangieri, Claudia Miccolo, Lucia Limido, Gianluigi Forloni, Fabrizio Tagliavini, Mario Salmona
Published 2008-01-01

V363I and V363A mutated tau affect aggregation and neuronal dysfunction differently in C. elegans

by Federica Morelli, Margherita Romeo, Maria Monica Barzago, Marco Bolis, Davide Mattioni, Giacomina Rossi, Fabrizio Tagliavini, Antonio Bastone, Mario Salmona, Luisa Diomede
Published 2018-09-01

The new β amyloid-derived peptide Aβ1–6A2V-TAT(D) prevents Aβ oligomer formation and protects transgenic C. elegans from Aβ toxicity

by Luisa Diomede, Margherita Romeo, Alfredo Cagnotto, Alessandro Rossi, Marten Beeg, Matteo Stravalaci, Fabrizio Tagliavini, Giuseppe Di Fede, Marco Gobbi, Mario Salmona
Published 2016-04-01

C. elegans expressing human β2-microglobulin: a novel model for studying the relationship between the molecular assembly and the toxic phenotype.

by Luisa Diomede, Cristina Soria, Margherita Romeo, Sofia Giorgetti, Loredana Marchese, Patrizia Palma Mangione, Riccardo Porcari, Irene Zorzoli, Mario Salmona, Vittorio Bellotti, Monica Stoppini
Published 2012-01-01

C. elegans detects toxicity of traumatic brain injury generated tau

by Elisa R. Zanier, Maria Monica Barzago, Gloria Vegliante, Margherita Romeo, Elena Restelli, Ilaria Bertani, Carmina Natale, Luca Colnaghi, Laura Colombo, Luca Russo, Edoardo Micotti, Luana Fioriti, Roberto Chiesa, Luisa Diomede
Published 2021-06-01

Machine learning analyses of antibody somatic mutations predict immunoglobulin light chain toxicity

by Maura Garofalo, Luca Piccoli, Margherita Romeo, Maria Monica Barzago, Sara Ravasio, Mathilde Foglierini, Milos Matkovic, Jacopo Sgrignani, Raoul De Gasparo, Marco Prunotto, Luca Varani, Luisa Diomede, Olivier Michielin, Antonio Lanzavecchia, Andrea Cavalli
Published 2021-06-01

Expression of A2V-mutated Aβ in Caenorhabditis elegans results in oligomer formation and toxicity

by Luisa Diomede, Giuseppe Di Fede, Margherita Romeo, Renzo Bagnati, Roberta Ghidoni, Fabio Fiordaliso, Monica Salio, Alessandro Rossi, Marcella Catania, Anna Paterlini, Luisa Benussi, Antonio Bastone, Matteo Stravalaci, Marco Gobbi, Fabrizio Tagliavini, Mario Salmona
Published 2014-02-01

Multigram Synthesis and in Vivo Efficacy Studies of a Novel Multitarget Anti-Alzheimer’s Compound

by Irene Sola, Elisabet Viayna, Tània Gómez, Carles Galdeano, Matteo Cassina, Pelayo Camps, Margherita Romeo, Luisa Diomede, Mario Salmona, Pilar Franco, Mireille Schaeffer, Diego Colantuono, David Robin, Daniela Brunner, Nicole Taub, Birgit Hutter-Paier, Diego Muñoz-Torrero
Published 2015-03-01

Doxycycline Inhibition of a Pseudotyped Virus Transduction Does Not Translate to Inhibition of SARS-CoV-2 Infectivity

by Luisa Diomede, Sara Baroni, Ada De Luigi, Arianna Piotti, Jacopo Lucchetti, Claudia Fracasso, Luca Russo, Valerio Bonaldo, Nicolò Panini, Federica Filippini, Fabio Fiordaliso, Alessandro Corbelli, Marten Beeg, Massimo Pizzato, Francesca Caccuri, Marco Gobbi, Emiliano Biasini, Arnaldo Caruso, Mario Salmona
Published 2021-09-01