The N-terminal, polybasic region is critical for prion protein neuroprotective activity.

by Jessie A Turnbaugh, Laura Westergard, Ursula Unterberger, Emiliano Biasini, David A Harris
Published 2011-01-01

The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells.

by Emiliano Biasini, Jessie A Turnbaugh, Tania Massignan, Pietro Veglianese, Gianluigi Forloni, Valentina Bonetto, Roberto Chiesa, David A Harris
Published 2012-01-01