Distinct DNA Methylation Patterns of Rheumatoid Arthritis Peripheral Blood and Synovial Tissue T Cells

by Rizi Ai, David L. Boyle, Wei Wang, Gary S. Firestein
Published 2021-03-01

PUMA gene delivery to synoviocytes reduces inflammation and degeneration of arthritic joints

by Saw-See Hong, Hubert Marotte, Guillaume Courbon, Gary S. Firestein, Pierre Boulanger, Pierre Miossec
Published 2017-07-01

Joint Location–Specific JAK‐STAT Signaling in Rheumatoid Arthritis Fibroblast‐like Synoviocytes

by Deepa Hammaker, Gyrid Nygaard, Amanda Kuhs, Rizi Ai, David L. Boyle, Wei Wang, Gary S. Firestein
Published 2019-12-01

Correction: Integrative Omics Analysis of Rheumatoid Arthritis Identifies Non-Obvious Therapeutic Targets.

by John W Whitaker, David L Boyle, Beatrix Bartok, Scott T Ball, Steffen Gay, Wei Wang, Gary S Firestein
Published 2015-01-01

Integrative omics analysis of rheumatoid arthritis identifies non-obvious therapeutic targets.

by John W Whitaker, David L Boyle, Beatrix Bartok, Scott T Ball, Steffen Gay, Wei Wang, Gary S Firestein
Published 2015-01-01

Histamine and Histamine H4 Receptor Promotes Osteoclastogenesis in Rheumatoid Arthritis

by Kyoung-Woon Kim, Bo-Mi Kim, Kyung-Ann Lee, Sang-Heon Lee, Gary S. Firestein, Hae-Rim Kim
Published 2017-04-01

Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes

by Rizi Ai, Deepa Hammaker, David L. Boyle, Rachel Morgan, Alice M. Walsh, Shicai Fan, Gary S. Firestein, Wei Wang
Published 2016-06-01

Correction: Differential Roles of MAPK Kinases MKK3 and MKK6 in Osteoclastogenesis and Bone Loss

by David L. Boyle, Deepa Hammaker, Meghan Edgar, Mario M. Zaiss, Stefan Teufel, Jean Pierre David, Georg Schett, Gary S. Firestein
Published 2014-01-01

Correction: Differential Roles of MAPK Kinases MKK3 and MKK6 in Osteoclastogenesis and Bone Loss.

by David L. Boyle, Deepa Hammaker, Meghan Edgar, Mario M. Zaiss, Stefan Teufel, Jean Pierre David, Georg Schett, Gary S. Firestein
Published 2014-01-01

Differential roles of MAPK kinases MKK3 and MKK6 in osteoclastogenesis and bone loss.

by David L Boyle, Deepa Hammaker, Meghan Edgar, Mario M Zaiss, Stefan Teufel, Jean Pierre David, Georg Schett, Gary S Firestein
Published 2014-01-01

Regulation of peripheral inflammation by spinal p38 MAP kinase in rats.

by David L Boyle, Toni L Jones, Deepa Hammaker, Camille I Svensson, Sanna Rosengren, Salvatore Albani, Linda Sorkin, Gary S Firestein
Published 2006-09-01

Tender and swollen joint counts are poorly associated with disability in chikungunya arthritis compared to rheumatoid arthritis

by Hugh Watson, Ramão Luciano Nogueira-Hayd, Maony Rodrigues-Moreno, Felipe Naveca, Giulia Calusi, Karol Suchowiecki, Gary S. Firestein, Gary Simon, Aileen Y. Chang
Published 2021-09-01

Role of interleukin 17 in arthritis chronicity through survival of synoviocytes via regulation of synoviolin expression.

by Myew-Ling Toh, Gaelle Gonzales, Marije I Koenders, Anne Tournadre, David Boyle, Erik Lubberts, Yuan Zhou, Gary S Firestein, Wim B van den Berg, Pierre Miossec
Published 2010-10-01

The Cytokine Profile in Acute Chikungunya Infection is Predictive of Chronic Arthritis 20 Months Post Infection

by Aileen Y. Chang, Sarah Tritsch, St. Patrick Reid, Karen Martins, Liliana Encinales, Nelly Pacheco, Richard L. Amdur, Alexandra Porras-Ramirez, Alejandro Rico-Mendoza, Guangzhao Li, Jin Peng, Gary S. Firestein, Gary L. Simon, Jeff M. Bethony
Published 2018-10-01

Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes

by Rizi Ai, Teresina Laragione, Deepa Hammaker, David L. Boyle, Andre Wildberg, Keisuke Maeshima, Emanuele Palescandolo, Vinod Krishna, David Pocalyko, John W. Whitaker, Yuchen Bai, Sunil Nagpal, Kurtis E. Bachman, Richard I. Ainsworth, Mengchi Wang, Bo Ding, Percio S. Gulko, Wei Wang, Gary S. Firestein
Published 2018-05-01

Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis

by Denise Beckmann, Anja Römer-Hillmann, Annika Krause, Uwe Hansen, Corinna Wehmeyer, Johanna Intemann, David J. J. de Gorter, Berno Dankbar, Jan Hillen, Marianne Heitzmann, Isabell Begemann, Milos Galic, Toni Weinhage, Dirk Foell, Rizi Ai, Joachim Kremerskothen, Hans P. Kiener, Sylvia Müller, Thomas Kamradt, Christopher Schröder, Elsa Leitão, Bernhard Horsthemke, Philip Rosenstiel, Karl Nordström, Gilles Gasparoni, Nina Gasparoni, Jörn Walter, Na Li, Xinyi Yang, Ho-Ryun Chung, Hermann Pavenstädt, Nico Lindemann, Hans J. Schnittler, Wei Wang, Gary S. Firestein, Thomas Pap, Adelheid Korb-Pap
Published 2021-06-01

Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue

by Laura T. Donlin, Deepak A. Rao, Kevin Wei, Kamil Slowikowski, Mandy J. McGeachy, Jason D. Turner, Nida Meednu, Fumitaka Mizoguchi, Maria Gutierrez-Arcelus, David J. Lieb, Joshua Keegan, Kaylin Muskat, Joshua Hillman, Cristina Rozo, Edd Ricker, Thomas M. Eisenhaure, Shuqiang Li, Edward P. Browne, Adam Chicoine, Danielle Sutherby, Akiko Noma, Accelerating Medicines Partnership RA/SLE Network, Chad Nusbaum, Stephen Kelly, Alessandra B. Pernis, Lionel B. Ivashkiv, Susan M. Goodman, William H. Robinson, Paul J. Utz, James A. Lederer, Ellen M. Gravallese, Brendan F. Boyce, Nir Hacohen, Costantino Pitzalis, Peter K. Gregersen, Gary S. Firestein, Soumya Raychaudhuri, Larry W. Moreland, V. Michael Holers, Vivian P. Bykerk, Andrew Filer, David L. Boyle, Michael B. Brenner, Jennifer H. Anolik
Published 2018-07-01