Breathing fresh air into respiratory research with single-cell RNA sequencing

by Michael J. Alexander, G.R. Scott Budinger, Paul A. Reyfman
Published 2020-07-01

The heterogeneity of lung macrophages in the susceptibility to disease

by Luisa Morales-Nebreda, Alexander V. Misharin, Harris Perlman, G.R. Scott Budinger
Published 2015-09-01

BH3 peptides induce mitochondrial fission and cell death independent of BAX/BAK.

by Emelyn H Shroff, Colleen M Snyder, G R Scott Budinger, Manu Jain, Teng-Leong Chew, Satya Khuon, Harris Perlman, Navdeep S Chandel
Published 2009-05-01

Nitric oxide prevents alveolar senescence and emphysema in a mouse model.

by Amanda E Boe, Mesut Eren, Luisa Morales-Nebreda, Sheila B Murphy, G R Scott Budinger, Gökhan M Mutlu, Toshio Miyata, Douglas E Vaughan
Published 2015-01-01

Alcohol worsens acute lung injury by inhibiting alveolar sodium transport through the adenosine A1 receptor.

by Laura Dada, Angel R Gonzalez, Daniela Urich, Saul Soberanes, Tomas S Manghi, Sergio E Chiarella, Navdeep S Chandel, G R Scott Budinger, Gökhan M Mutlu
Published 2012-01-01

SIRT3 Overexpression Ameliorates Asbestos-Induced Pulmonary Fibrosis, mt-DNA Damage, and Lung Fibrogenic Monocyte Recruitment

by Paul Cheresh, Seok-Jo Kim, Renea Jablonski, Satoshi Watanabe, Ziyan Lu, Monica Chi, Kathryn A. Helmin, David Gius, G. R. Scott Budinger, David W. Kamp
Published 2021-06-01

The effect of rosuvastatin in a murine model of influenza A infection.

by Kathryn A Radigan, Daniela Urich, Alexander V Misharin, Sergio E Chiarella, Saul Soberanes, Angel Gonzalez, Harris Perlman, Richard G Wunderink, G R Scott Budinger, Gökhan M Mutlu
Published 2012-01-01

Impaired clearance of influenza A virus in obese, leptin receptor deficient mice is independent of leptin signaling in the lung epithelium and macrophages.

by Kathryn A Radigan, Luisa Morales-Nebreda, Saul Soberanes, Trevor Nicholson, Recep Nigdelioglu, Takugo Cho, Monica Chi, Robert B Hamanaka, Alexander V Misharin, Harris Perlman, G R Scott Budinger, Gökhan M Mutlu
Published 2014-01-01

Tenascin-C drives persistence of organ fibrosis

by Swati Bhattacharyya, Wenxia Wang, Luisa Morales-Nebreda, Gang Feng, Minghua Wu, Xiaodong Zhou, Robert Lafyatis, Jungwha Lee, Monique Hinchcliff, Carol Feghali-Bostwick, Katja Lakota, G. R. Scott Budinger, Kirtee Raparia, Zenshiro Tamaki, John Varga
Published 2016-06-01

Nonclassical Ly6C− Monocytes Drive the Development of Inflammatory Arthritis in Mice

by Alexander V. Misharin, Carla M. Cuda, Rana Saber, Jason D. Turner, Angelica K. Gierut, G. Kenneth Haines III, Sergejs Berdnikovs, Andrew Filer, Andrew R. Clark, Christopher D. Buckley, Gökhan M. Mutlu, G.R. Scott Budinger, Harris Perlman
Published 2014-10-01

Evolutionary conserved role of c-Jun-N-terminal kinase in CO2-induced epithelial dysfunction.

by István Vadász, Laura A Dada, Arturo Briva, Iiro Taneli Helenius, Kfir Sharabi, Lynn C Welch, Aileen M Kelly, Benno A Grzesik, G R Scott Budinger, Jing Liu, Werner Seeger, Greg J Beitel, Yosef Gruenbaum, Jacob I Sznajder
Published 2012-01-01

The Sphingosine Kinase 1 Inhibitor, PF543, Mitigates Pulmonary Fibrosis by Reducing Lung Epithelial Cell mtDNA Damage and Recruitment of Fibrogenic Monocytes

by Paul Cheresh, Seok-Jo Kim, Long Shuang Huang, Satoshi Watanabe, Nikita Joshi, Kinola J.N. Williams, Monica Chi, Ziyan Lu, Anantha Harijith, Anjana Yeldandi, Anna P. Lam, Cara Gottardi, Alexander V. Misharin, G.R. Scott Budinger, Viswanathan Natarajan, David W. Kamp
Published 2020-08-01

Inflammatory pathways are upregulated in the nasal epithelium in patients with idiopathic pulmonary fibrosis

by Marc A. Sala, Yalbi Itzel Balderas-Martínez, Ivette Buendía-Roldan, Hiam Abdala-Valencia, Kiwon Nam, Manu Jain, Sangeeta Bhorade, Ankit Bharat, Paul A. Reyfman, Karen M. Ridge, Annie Pardo, Jacob I. Sznajder, G. R. Scott Budinger, Alexander V. Misharin, Moises Selman
Published 2018-11-01

Particulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms.

by G R Scott Budinger, Joanne L McKell, Daniela Urich, Nancy Foiles, Ivy Weiss, Sergio E Chiarella, Angel Gonzalez, Saul Soberanes, Andrew J Ghio, Recep Nigdelioglu, Ece A Mutlu, Kathryn A Radigan, David Green, Hau C Kwaan, Gökhan M Mutlu
Published 2011-04-01

Crosstalk between nonclassical monocytes and alveolar macrophages mediates transplant ischemia-reperfusion injury through classical monocyte recruitment

by Chitaru Kurihara, Emilia Lecuona, Qiang Wu, Wenbin Yang, Félix L. Núñez-Santana, Mahzad Akbarpour, Xianpeng Liu, Ziyou Ren, Wenjun Li, Melissa Querrey, Sowmya Ravi, Megan L. Anderson, Emily Cerier, Haiying Sun, Megan E. Kelly, Hiam Abdala-Valencia, Ali Shilatifard, Thalachallour Mohanakumar, G.R. Scott Budinger, Daniel Kreisel, Ankit Bharat
Published 2021-03-01