Mutation in LEMD3 (Man1) Associated with Osteopoikilosis and Late-Onset Generalized Morphea: A New Buschke-Ollendorf Syndrome Variant

by Benjamin Korman, Jun Wei, Anne Laumann, Polly Ferguson, John Varga
Published 2016-01-01

The transcriptional cofactor nab2 is induced by tgf-Beta and suppresses fibroblast activation: physiological roles and impaired expression in scleroderma.

by Swati Bhattacharyya, Jun Wei, Denisa S Melichian, Jeffrey Milbrandt, Kazuhiko Takehara, John Varga
Published 2009-10-01

Adipocyte-specific Repression of PPAR-gamma by NCoR Contributes to Scleroderma Skin Fibrosis

by Benjamin Korman, Roberta Goncalves Marangoni, Gabriel Lord, Jerrold Olefsky, Warren Tourtellotte, John Varga
Published 2018-07-01

Adiponectin Deregulation in Systemic Autoimmune Rheumatic Diseases

by Neža Brezovec, Katja Perdan-Pirkmajer, Saša Čučnik, Snežna Sodin-Šemrl, John Varga, Katja Lakota
Published 2021-04-01

Pharmacological Inhibition of Toll-Like Receptor-4 Signaling by TAK242 Prevents and Induces Regression of Experimental Organ Fibrosis

by Swati Bhattacharyya, Wenxia Wang, Zenshiro Tamaki, Bo Shi, Anjana Yeldandi, Yasuhiro Tsukimi, Masashi Yamasaki, John Varga
Published 2018-10-01

A recrystallization heat-treatment to reduce deformation anisotropy of additively manufactured Inconel 718

by Nadia Kouraytem, John Varga, Behnam Amin-Ahmadi, Hadi Mirmohammad, Raphaël A. Chanut, Ashley D. Spear, Owen T. Kingstedt
Published 2021-01-01

Early stage lung cancer detection in systemic sclerosis does not portend survival benefit: a cross sectional study.

by Jeremy B Katzen, Kirtee Raparia, Rishi Agrawal, Jyoti D Patel, Alfred Rademaker, John Varga, Jane E Dematte
Published 2015-01-01

Egr-1 induces a profibrotic injury/repair gene program associated with systemic sclerosis.

by Swati Bhattacharyya, Jennifer L Sargent, Pan Du, Simon Lin, Warren G Tourtellotte, Kazuhiko Takehara, Michael L Whitfield, John Varga
Published 2011-01-01

Serum amyloid A is a marker for pulmonary involvement in systemic sclerosis.

by Katja Lakota, Mary Carns, Sofia Podlusky, Katjusa Mrak-Poljsak, Monique Hinchcliff, Jungwha Lee, Matija Tomsic, Snezna Sodin-Semrl, John Varga
Published 2015-01-01

Fibronectin EDA forms the chronic fibrotic scar after contusive spinal cord injury

by John G. Cooper, Su Ji Jeong, Tammy L. McGuire, Sripadh Sharma, Wenxia Wang, Swati Bhattacharyya, John Varga, John A. Kessler
Published 2018-08-01

Experimentally-derived fibroblast gene signatures identify molecular pathways associated with distinct subsets of systemic sclerosis patients in three independent cohorts.

by Michael E Johnson, J Matthew Mahoney, Jaclyn Taroni, Jennifer L Sargent, Eleni Marmarelis, Ming-Ru Wu, John Varga, Monique E Hinchcliff, Michael L Whitfield
Published 2015-01-01

PPARγ downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis.

by Jun Wei, Asish K Ghosh, Jennifer L Sargent, Kazuhiro Komura, Minghua Wu, Qi-Quan Huang, Manu Jain, Michael L Whitfield, Carol Feghali-Bostwick, John Varga
Published 2010-11-01

HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatus.

by Markus Schrettl, Nicola Beckmann, John Varga, Thorsten Heinekamp, Ilse D Jacobsen, Christoph Jöchl, Tarek A Moussa, Shaohua Wang, Fabio Gsaller, Michael Blatzer, Ernst R Werner, William C Niermann, Axel A Brakhage, Hubertus Haas
Published 2010-09-01

Tenascin-C drives persistence of organ fibrosis

by Swati Bhattacharyya, Wenxia Wang, Luisa Morales-Nebreda, Gang Feng, Minghua Wu, Xiaodong Zhou, Robert Lafyatis, Jungwha Lee, Monique Hinchcliff, Carol Feghali-Bostwick, Katja Lakota, G. R. Scott Budinger, Kirtee Raparia, Zenshiro Tamaki, John Varga
Published 2016-06-01

Novel lung imaging biomarkers and skin gene expression subsetting in dasatinib treatment of systemic sclerosis-associated interstitial lung disease.

by Viktor Martyanov, Grace-Hyun J Kim, Wendy Hayes, Shuyan Du, Bishu J Ganguly, Oumar Sy, Sun Ku Lee, Galina S Bogatkevich, Gary L Schieven, Elena Schiopu, Roberta Gonçalves Marangoni, Jonathan Goldin, Michael L Whitfield, John Varga
Published 2017-01-01

Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target

by Roberta G. Marangoni, Yuri Masui, Feng Fang, Benjamin Korman, Gabriel Lord, Junghwa Lee, Katja Lakota, Jun Wei, Philipp E. Scherer, Laszlo Otvos, Toshimasa Yamauchi, Naoto Kubota, Takashi Kadowaki, Yoshihide Asano, Shinichi Sato, Warren G. Tourtellotte, John Varga
Published 2017-06-01

The MUC5B variant is associated with idiopathic pulmonary fibrosis but not with systemic sclerosis interstitial lung disease in the European Caucasian population.

by Raphael Borie, Bruno Crestani, Philippe Dieude, Hilario Nunes, Yannick Allanore, Caroline Kannengiesser, Paolo Airo, Marco Matucci-Cerinic, Benoit Wallaert, Dominique Israel-Biet, Jacques Cadranel, Vincent Cottin, Steven Gazal, Anna L Peljto, John Varga, David A Schwartz, Dominique Valeyre, Bernard Grandchamp
Published 2013-01-01

Clinical characteristics, visceral involvement, and mortality in at-risk or early diffuse systemic sclerosis: a longitudinal analysis of an observational prospective multicenter US...

by Sara Jaafar, Alain Lescoat, Suiyuan Huang, Jessica Gordon, Monique Hinchcliff, Ami A. Shah, Shervin Assassi, Robyn Domsic, Elana J. Bernstein, Virginia Steen, Sabrina Elliott, Faye Hant, Flavia V. Castelino, Victoria K. Shanmugam, Chase Correia, John Varga, Vivek Nagaraja, David Roofeh, Tracy Frech, Dinesh Khanna
Published 2021-06-01

Targeting CD38-dependent NAD+ metabolism to mitigate multiple organ fibrosis

by Bo Shi, Wenxia Wang, Benjamin Korman, Li Kai, Qianqian Wang, Jun Wei, Swarna Bale, Roberta Goncalves Marangoni, Swati Bhattacharyya, Stephen Miller, Dan Xu, Mahzad Akbarpour, Paul Cheresh, Daniele Proccissi, Demirkan Gursel, Jair Machado Espindola-Netto, Claudia C.S. Chini, Guilherme C. de Oliveira, Johann E. Gudjonsson, Eduardo N. Chini, John Varga
Published 2021-01-01

Correction: Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy

by Olga Gorlova, Jose-Ezequiel Martin, Blanca Rueda, Bobby P. C. Koeleman, Jun Ying, Maria Teruel, Lina-Marcela Diaz-Gallo, Jasper C. Broen, Madelon C. Vonk, Carmen P. Simeon, Behrooz Z. Alizadeh, Marieke J. H. Coenen, Alexandre E. Voskuyl, Annemie J. Schuerwegh, Piet L. C. M. van Riel, Marie Vanthuyne, Ruben van 't Slot, Annet Italiaander, Roel A. Ophoff, Nicolas Hunzelmann, Vicente Fonollosa, Norberto Ortego-Centeno, Miguel A. González-Gay, Francisco J. García-Hernández, María F. González-Escribano, Paolo Airo, Jacob van Laar, Jane Worthington, Roger Hesselstrand, Vanessa Smith, Filip de Keyser, Fredric Houssiau, Meng May Chee, Rajan Madhok, Paul G. Shiels, Rene Westhovens, Alexander Kreuter, Elfride de Baere, Torsten Witte, Leonid Padyukov, Annika Nordin, Raffaella Scorza, Claudio Lunardi, Benedicte A. Lie, Anna-Maria Hoffmann-Vold, Øyvind Palm, Paloma García de la Peña, Patricia Carreira, Spanish Scleroderma Group, John Varga, Monique Hinchcliff, Annette T. Lee, Pravitt Gourh, Christopher I. Amos, Frederick M. Wigley, Laura K. Hummers, J. Lee Nelson, Gabriella Riemekasten, Ariane Herrick, Lorenzo Beretta, Carmen Fonseca, Christopher P. Denton, Peter K. Gregersen, Sandeep Agarwal, Shervin Assassi, Filemon K. Tan, Frank C. Arnett, Timothy R. D. J. Radstake, Maureen D. Mayes, Javier Martin
Published 2011-08-01