The Role of Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Lung Architecture Remodeling

by Anantha Harijith, Viswanathan Natarajan, Panfeng Fu
Published 2017-12-01

Lipid Mediators Regulate Pulmonary Fibrosis: Potential Mechanisms and Signaling Pathways

by Vidyani Suryadevara, Ramaswamy Ramchandran, David W. Kamp, Viswanathan Natarajan
Published 2020-06-01

Development and Validation of a Diabetic Retinopathy Referral Algorithm Based on Single-Field Fundus Photography.

by Sangeetha Srinivasan, Sharan Shetty, Viswanathan Natarajan, Tarun Sharma, Rajiv Raman
Published 2016-01-01

Four-year incidence and progression of visual impairment in a South Indian population with diabetes

by Sangeetha Srinivasan, Rajiv Raman, Suganeswari Ganesan, Rupak Roy, Viswanathan Natarajan, Tarun Sharma
Published 2017-01-01

Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair

by Qian Chen, Jalees Rehman, Manwai Chan, Panfeng Fu, Steven M. Dudek, Viswanathan Natarajan, Asrar B. Malik, Yuru Liu
Published 2020-06-01

The Roles of Sphingosine Kinase 1 and 2 in Regulating the Metabolome and Survival of Prostate Cancer Cells

by Nigel J. Pyne, Susan Pyne, David G. Watson, Robert Bittman, Evgeny Berdyshev, Irina Gorshkova, Francesca Tonelli, Viswanathan Natarajan, Manal Alossaimi
Published 2013-06-01

Essential role for paxillin tyrosine phosphorylation in LPS-induced mitochondrial fission, ROS generation and lung endothelial barrier loss

by Panfeng Fu, Yulia Epshtein, Ramaswamy Ramchandran, Joseph B. Mascarenhas, Anne E. Cress, Jeffrey Jacobson, Joe G. N. Garcia, Viswanathan Natarajan
Published 2021-09-01

All-Trans Retinoic Acid Induces TGF-β2 in Intestinal Epithelial Cells via RhoA- and p38α MAPK-Mediated Activation of the Transcription Factor ATF2.

by Kopperuncholan Namachivayam, Krishnan MohanKumar, Dima Arbach, Ramasamy Jagadeeswaran, Sunil K Jain, Viswanathan Natarajan, Dolly Mehta, Robert P Jankov, Akhil Maheshwari
Published 2015-01-01

Genetic deletion of Sphk2 confers protection against Pseudomonas aeruginosa mediated differential expression of genes related to virulent infection and inflammation in mouse lung

by David L. Ebenezer, Panfeng Fu, Yashaswin Krishnan, Mark Maienschein-Cline, Hong Hu, Segun Jung, Ravi Madduri, Zarema Arbieva, Anantha Harijith, Viswanathan Natarajan
Published 2019-12-01

Clinico-Pathological Association of Delineated miRNAs in Uveal Melanoma with Monosomy 3/Disomy 3 Chromosomal Aberrations.

by Nalini Venkatesan, Jagat Kanwar, Perinkulam Ravi Deepa, Vikas Khetan, Tamsyn M Crowley, Rajeswari Raguraman, Ganesan Sugneswari, Pukhraj Rishi, Viswanathan Natarajan, Jyotirmay Biswas, Subramanian Krishnakumar
Published 2016-01-01

Intracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells: role of sphingosine kinase 1 and S1P lyase.

by Evgeny V Berdyshev, Irina Gorshkova, Peter Usatyuk, Satish Kalari, Yutong Zhao, Nigel J Pyne, Susan Pyne, Roger A Sabbadini, Joe G N Garcia, Viswanathan Natarajan
Published 2011-01-01

NOX4 Mediates <i>Pseudomonas Aeruginosa</i>-Induced Nuclear Reactive Oxygen Species Generation and Chromatin Remodeling in Lung Epithelium

by Panfeng Fu, Ramaswamy Ramchandran, Tara Sudhadevi, Prasanth P.K. Kumar, Yashaswin Krishnan, Yuru Liu, Yutong Zhao, Narasimham L. Parinandi, Anantha Harijith, Junichi Sadoshima, Viswanathan Natarajan
Published 2021-03-01

SPHK2-Generated S1P in CD11b+ Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages

by Jagdish C. Joshi, Bhagwati Joshi, Ian Rochford, Sheikh Rayees, Md Zahid Akhter, Sukriti Baweja, Koteshwara Rao Chava, Mohammad Tauseef, Hazem Abdelkarim, Viswanathan Natarajan, Vadim Gaponenko, Dolly Mehta
Published 2020-03-01

Role of protein kinase C β and vascular endothelial growth factor receptor in malignant pleural mesothelioma: Therapeutic implications and the usefulness of Caenorhabditis elegans...

by Sivakumar Loganathan, Rajani Kanteti, Shahid S Siddiqui, Essam El-Hashani, Maria Tretiakova, Hari Vigneswaran, Gustavo Cervantes, Viswanathan Natarajan, Aliya N Husain, Everett E Vokes, Hedy L Kindler, Ravi Salgia
Published 2011-01-01

Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression[S]

by Irina Gorshkova, Tong Zhou, Biji Mathew, Jeffrey R. Jacobson, Daisuke Takekoshi, Palash Bhattacharya, Brett Smith, Bulent Aydogan, Ralph R. Weichselbaum, Viswanathan Natarajan, Joe G.N. Garcia, Evgeny V. Berdyshev
Published 2012-08-01

Coronin 1B regulates S1P-induced human lung endothelial cell chemotaxis: role of PLD2, protein kinase C and Rac1 signal transduction.

by Peter V Usatyuk, Michael Burns, Vijay Mohan, Srikanth Pendyala, Donghong He, David L Ebenezer, Anantha Harijith, Panfeng Fu, Long Shuang Huang, James E Bear, Joe G N Garcia, Viswanathan Natarajan
Published 2013-01-01

Expression profiling of genes regulated by sphingosine kinase1 signaling in a murine model of hyperoxia induced neonatal bronchopulmonary dysplasia

by Viswanathan Natarajan, Alison W. Ha, Yangbasai Dong, Narsa M. Reddy, David L. Ebenezer, Prasad Kanteti, Sekhar P. Reddy, J. Usha Raj, Zhengdeng Lei, Mark Maienschein-Cline, Zarema Arbieva, Anantha Harijith
Published 2017-08-01

Sphingosine kinase 1 is required for mesothelioma cell proliferation: role of histone acetylation.

by Satish Kalari, Nagabhushan Moolky, Srikanth Pendyala, Evgeny V Berdyshev, Cleo Rolle, Rajani Kanteti, Archana Kanteti, Wenli Ma, Donghong He, Aliya N Husain, Hedy L Kindler, Prasad Kanteti, Ravi Salgia, Viswanathan Natarajan
Published 2012-01-01

Sphingosine Kinase 1/S1P Signaling Contributes to Pulmonary Fibrosis by Activating Hippo/YAP Pathway and Mitochondrial Reactive Oxygen Species in Lung Fibroblasts

by Long Shuang Huang, Tara Sudhadevi, Panfeng Fu, Prasanth-Kumar Punathil-Kannan, David Lenin Ebenezer, Ramaswamy Ramchandran, Vijay Putherickal, Paul Cheresh, Guofei Zhou, Alison W. Ha, Anantha Harijith, David W. Kamp, Viswanathan Natarajan
Published 2020-03-01

Light-regulated allosteric switch enables temporal and subcellular control of enzyme activity

by Mark Shaaya, Jordan Fauser, Anastasia Zhurikhina, Jason E Conage-Pough, Vincent Huyot, Martin Brennan, Cameron T Flower, Jacob Matsche, Shahzeb Khan, Viswanathan Natarajan, Jalees Rehman, Pradeep Kota, Forest M White, Denis Tsygankov, Andrei V Karginov
Published 2020-09-01