3D Reconstruction of the Neurovascular Unit Reveals Differential Loss of Cholinergic Innervation in the Cortex and Hippocampus of the Adult Mouse Brain

by Shereen Nizari, Roxana O. Carare, Ignacio A. Romero, Cheryl A. Hawkes
Published 2019-07-01

A three-dimensional model of the human blood-brain barrier to analyse the transport of nanoparticles and astrocyte/endothelial interactions [version 2; referees: 2 approved]

by Peddagangannagari Sreekanthreddy, Radka Gromnicova, Heather Davies, James Phillips, Ignacio A. Romero, David Male
Published 2016-01-01

Loss of cholinergic innervation differentially affects eNOS-mediated blood flow, drainage of Aβ and cerebral amyloid angiopathy in the cortex and hippocampus of adult mice

by Shereen Nizari, Jack A. Wells, Roxana O. Carare, Ignacio A. Romero, Cheryl A. Hawkes
Published 2021-01-01

Transport of Gold Nanoparticles by Vascular Endothelium from Different Human Tissues.

by Radka Gromnicova, Mehmet Kaya, Ignacio A Romero, Phil Williams, Simon Satchell, Basil Sharrack, David Male
Published 2016-01-01

Transcellular targeting of fiber- and hexon-modified adenovirus vectors across the brain microvascular endothelial cells in vitro.

by Johanna P Laakkonen, Tatjana Engler, Ignacio A Romero, Babette Weksler, Pierre-Olivier Couraud, Florian Kreppel, Stefan Kochanek
Published 2012-01-01

Cerebrospinal fluid dynamics modulation by diet and cytokines in rats

by Zerin Alimajstorovic, Ester Pascual-Baixauli, Cheryl A. Hawkes, Basil Sharrack, A. Jane Loughlin, Ignacio A. Romero, Jane E. Preston
Published 2020-02-01

Glucose-coated gold nanoparticles transfer across human brain endothelium and enter astrocytes in vitro.

by Radka Gromnicova, Heather A Davies, Peddagangannagari Sreekanthreddy, Ignacio A Romero, Torben Lund, Ivan M Roitt, James B Phillips, David K Male
Published 2013-01-01

A multi-system approach assessing the interaction of anticonvulsants with P-gp.

by David Dickens, Siti R Yusof, N Joan Abbott, Babette Weksler, Ignacio A Romero, Pierre-Olivier Couraud, Ana Alfirevic, Munir Pirmohamed, Andrew Owen
Published 2013-01-01

Prolonged Morphine Exposure Induces Increased Firm Adhesion in an in Vitro Model of the Blood–Brain Barrier

by Marianne Strazza, Vanessa Pirrone, Brian Wigdahl, Will Dampier, Wei Lin, Rui Feng, Monique E. Maubert, Babette Weksler, Ignacio A. Romero, Pierre-Olivier Couraud, Michael R. Nonnemacher
Published 2016-06-01

Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway

by Vanja Vukic, Debbie Callaghan, Douglas Walker, Lih-Fen Lue, Qing Yan Liu, Pierre-Oliver Couraud, Ignacio A. Romero, Babette Weksler, Danica B. Stanimirovic, Wandong Zhang
Published 2009-04-01

High Levels of Receptor Tyrosine Kinases in CCM3-Deficient Cells Increase Their Susceptibility to Tyrosine Kinase Inhibition

by Miriam Sartages, Ebel Floridia, Mar García-Colomer, Cristina Iglesias, Manuel Macía, Patricia Peñas, Pierre-Olivier Couraud, Ignacio A. Romero, Babette Weksler, Celia M. Pombo, Juan Zalvide
Published 2020-12-01

Drug-induced trafficking of p-glycoprotein in human brain capillary endothelial cells as demonstrated by exposure to mitomycin C.

by Andreas Noack, Sandra Noack, Andrea Hoffmann, Katia Maalouf, Manuela Buettner, Pierre-Olivier Couraud, Ignacio A Romero, Babette Weksler, Dana Alms, Kerstin Römermann, Hassan Y Naim, Wolfgang Löscher
Published 2014-01-01

Age-Associated mRNA and miRNA Expression Changes in the Blood-Brain Barrier

by Emily F. Goodall, Vicki Leach, Chunfang Wang, Johnathan Cooper-Knock, Paul R. Heath, David Baker, David R. Drew, M. Jill Saffrey, Julie E. Simpson, Ignacio A. Romero, Stephen B. Wharton
Published 2019-06-01

Endothelial-Derived Extracellular Vesicles Induce Cerebrovascular Dysfunction in Inflammation

by David Roig-Carles, Eduard Willms, Ruud D. Fontijn, Sarai Martinez-Pacheco, Imre Mäger, Helga E. de Vries, Mark Hirst, Basil Sharrack, David K. Male, Cheryl A. Hawkes, Ignacio A. Romero
Published 2021-09-01

Alteration of blood-brain barrier integrity by retroviral infection.

by Philippe V Afonso, Simona Ozden, Marie-Christine Cumont, Danielle Seilhean, Luis Cartier, Payam Rezaie, Sarah Mason, Sophie Lambert, Michel Huerre, Antoine Gessain, Pierre-Olivier Couraud, Claudine Pique, Pierre-Emmanuel Ceccaldi, Ignacio A Romero
Published 2008-11-01

Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017

by John Greenwood, Margareta Hammarlund-Udenaes, Hazel C. Jones, Alan W. Stitt, Roosmarijn E. Vandenbroucke, Ignacio A. Romero, Matthew Campbell, Gert Fricker, Birger Brodin, Heiko Manninga, Pieter J. Gaillard, Markus Schwaninger, Carl Webster, Krzysztof B. Wicher, Michel Khrestchatisky
Published 2017-11-01

Correction to: Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017

by John Greenwood, Margareta Hammarlund-Udenaes, Hazel C. Jones, Alan W. Stitt, Roosmarijn E. Vandenbroucke, Ignacio A. Romero, Matthew Campbell, Gert Fricker, Birger Brodin, Heiko Manninga, Pieter J. Gaillard, Markus Schwaninger, Carl Webster, Krzysztof B. Wicher, Michel Khrestchatisky
Published 2018-01-01

Abstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers

by Andrzej Małecki, Janina Skipor-Lahuta, Michal Toborek, N. Joan Abbott, David A. Antonetti, Enming Joe Su, Daniel A. Lawrence, Müge Atış, Uğur Akcan, Canan Uğur Yılmaz, Nurcan Orhan, Poyraz Düzgün, Umut Deniz Ceylan, Nadir Arıcan, Serçin Karahüseyinoğlu, Gizem Nur Şahin, Bülent Ahıshalı, Mehmet Kaya, Sidar Aydin, Armelle Klopstein, Britta Engelhardt, Julia Baumann, Chih-Chieh Tsao, Sheng-Fu Huang, Omolara Ogunshola, Elizaveta B. Boytsova, Andrey V. Morgun, Elena D. Khilazheva, Elena A. Pozhilenkova, Yana V. Gorina, Galina P. Martynova, Alla B. Salmina, David Bueno, Jordi Garcia-Fernàndez, Victor Castro, Marta Skowronska, Michal Toborek, Matheus Uba Chupel, Luciele Guerra Minuzzi, Edith Filaire, Ana Maria Teixeira, Mariangela Corsi, Romain Versele, Andrea Fuso, Emmanuel Sevin, Cherubino Di Lorenzo, Rita Businaro, Laurence Fenart, Fabien Gosselet, Pietra Candela, Mária A. Deli, Conor Delaney, Eoin O’Keefe, Michael Farrell, Sarah Doyle, Matthew Campbell, Lester R. Drewes, A. Appelt-Menzel, A. Cubukova, M. Metzger, R. Fischer, David M. F. Francisco, Rémy Bruggmann, Alexa Fries, Kinga G. Blecharz, Josephin Wagner, Lars Winkler, Ulf Schneider, Peter Vajkoczy, Mikio Furuse, Lydia Gabbert, Christina Dilling, Dmitri Sisario, Vladimir Soukhoroukov, Malgorzata Burek, S. Guérit, E. Fidan, K. Devraj, C. J. Czupalla, J. Macas, S. Thom, K. H. Plate, H. Gerhardt, S. Liebner, András Harazin, Alexandra Bocsik, Judit Váradi, Ferenc Fenyvesi, Vilmos Tubak, Miklós Vecsernyés, Hans Christian Helms, Helle Sønderby Waagepetersen, Carsten Uhd Nielsen, Birger Brodin, Zsófia Hoyk, Melinda E. Tóth, Nikolett Lénárt, Brigitta Dukay, Ágnes Kittel, Judit Vígh, Szilvia Veszelka, Fruzsina Walter, Ágnes Zvara, László Puskás, Miklós Sántha, Sabrina Engelhardt, Omolara O. Ogunshola, Anna Huber, Alexander Reitner, Samar Osmen, Kathrin Hahn, Neli Bounzina, Anna Gerhartl, Anna Schönegger, Hannes Steinkellner, Franco Laccone, Winfried Neuhaus, Natalie Hudson, Lucia Celkova, Anne Iltzsche, Svetlana Drndarski, David J Begley, Mette Mathiesen Janiurek, Krzysztof Kucharz, Christina Christoffersen, Lars Bo Nielsen, Martin Lauritzen, Rebecca H Johnson, Dan T Kho, Simon J O’Carroll, Catherine E Angel, E. Scott Graham, Jennifer Pereira, Christina Simoglou Karali, Vinton Cheng, Niloufar Zarghami, Manuel Sarmiento Soto, Yvonne Couch, Daniel C. Anthony, Nicola R. Sibson, John Kealy, Richard F. Keep, Lisa J. Routhe, Jianming Xiang, Hong Ye, Ya Hua, Torben Moos, Guohua Xi, M. Kristensen, A. Bach, K. Strømgaard, Nikolay Kutuzov, Melissa A. Lopes-Pinheiro, Jamie Lim, Alwin Kamermans, Jack van Horssen, Wendy W.J. Unger, Ruud Fontijn, Helga E. de Vries, Petra Majerova, Ralph M. Garruto, Luca Marchetti, David Francisco, Isabelle Gruber, Ruth Lyck, Mária Mészáros, Gergő Porkoláb, Lóránd Kiss, Ana-Maria Pilbat, Zsolt Török, Zsolt Bozsó, Lívia Fülöp, Alena Michalicova, Jaroslav Galba, Sandra Mihaljevic, Michal Novak, Andrej Kovac, Yoichi Morofuji, Takashi Fujimoto, Daisuke Watanabe, Shinsuke Nakagawa, Kenta Ujifuku, Nobutaka Horie, Tsuyoshi Izumo, Takeo Anda, Takayuki Matsuo, Fang Niu, Shilpa Buch, Ádám Nyúl-Tóth, Mihály Kozma, Péter Nagyőszi, Krisztina Nagy, Csilla Fazakas, János Haskó, Kinga Molnár, Attila E. Farkas, Péter Galajda, Imola Wilhelm, István A. Krizbai, Eoin Kelly, Eugene Wallace, Chris Greene, Stephanie Hughes, John Kealy, Niamh Doyle, Marian M. Humphries, Gerald A. Grant, Alon Friedman, Ronel Veksler, Michael G. Molloy, James F. Meaney, Niall Pender, Colin P. Doherty, Minseon Park, Arkadiusz Liskiewicz, Marta Przybyla, Daniela Kasprowska-Liśkiewicz, Marta Nowacka-Chmielewska, Andrzej Malecki, Ana Pombero, Raquel Garcia-Lopez, Marta Martinez-Morga, Salvador Martinez, Ofer Prager, Lyna Solomon-Kamintsky, Karl Schoknecht, Guy Bar-Klein, Dan Milikovsky, Udi Vazana, Dror Rosenbach, Richard Kovács, Alon Friedman, Zsolt Radak, Sabela Rodríguez-Lorenzo, Remy Bruggmann, Gijs Kooij, Helga E de Vries, Semyachkina-Glushkovskaya Oxana, Bragin Denis, Vodovozova Elena, Alekseeva Anna, Salmina Alla, Salmin Vladimir, Morgun Andrey, Malinovskaya Nataliya, Khilazheva Elena, Boytsova Elizaveta, Shirokov Alexander, Navolokin Nikita, Bucharskaya Alla, Yang Yirong, Abdurashitov Arkady, Gekalyuk Artem, Ulanova Mariya, Shushunova Anastasia, Bodrova Madina, Sagatova Artem, Khorovodov Alexander, Shareef Ali Esmat, Pavlov Valery, Tuchin Artem, Kurths Jürgen, Marcelle Silva de Abreu, Ana C. Calpena, Marta Espina, Maria Luisa García, Ignacio A. Romero, David Male, Steffen Storck, Anika Hartz, Jens Pahnke, Claus U. Surma, M. Surma, Z. Giżejewski, H. Zieliński, Aleksandra Szczepkowska, Marta Kowalewska, Agata Krawczynska, Andrzej P. Herman, Janina Skipor, Nicole Kachappilly, Mike Veenstra, Rosiris Leon Rivera, Dionna W. Williams, Susan Morgello, Joan W. Berman, Ursula Wyneken, Luis Federico Batiz, Arzu Temizyürek, Rouhollah Khodadust, Mutlu Küçük, Candan Gürses, Serkan Emik, Magdalena Zielińska, Marta Obara-Michlewska, Krzysztof Milewski, Edyta Skonieczna, Inez Fręśko, Edward A. Neuwelt, Ana Raquel Santa Maria, Ana Rita Bras, Dóra Lipka, Sándor Valkai, András Kincses, András Dér, Maria A. Deli
Published 2017-10-01